NTDB

Overview

Name	cclA/cilC	Type	Machinery gene
Locus tag	LLWM1_RS10920	Genome accession	NZ_CP032500
Coordinates	2135745..2136410 (+)	Length	221 a.a.
NCBI ID	WP_004254535.1	Uniprot ID	Q9CE22
Organism	Lactococcus lactis subsp. lactis strain WM1
Function	processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2130745..2141410

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LLWM1_RS10890 (LLWM1_2087)	-	2131887..2132213 (-)	327	WP_010906269.1	lactococcin 972 family bacteriocin	-
LLWM1_RS10895 (LLWM1_2088)	-	2132513..2133241 (-)	729	WP_004254546.1	LytTR family transcriptional regulator DNA-binding domain-containing protein	-
LLWM1_RS10900 (LLWM1_2089)	-	2133434..2133655 (+)	222	WP_010906270.1	YqgQ family protein	-
LLWM1_RS10905 (LLWM1_2090)	-	2133689..2134660 (+)	972	WP_004254542.1	ROK family glucokinase	-
LLWM1_RS10910 (LLWM1_2091)	-	2134663..2135049 (+)	387	WP_004254540.1	rhodanese-like domain-containing protein	-
LLWM1_RS10915 (LLWM1_2092)	-	2135132..2135578 (-)	447	WP_004254538.1	DNA starvation/stationary phase protection protein	-
LLWM1_RS10920 (LLWM1_03155)	cclA/cilC	2135745..2136410 (+)	666	WP_004254535.1	A24 family peptidase	Machinery gene
LLWM1_RS10925 (LLWM1_2093)	dinB	2136361..2137452 (-)	1092	WP_058221601.1	DNA polymerase IV	-
LLWM1_RS10930 (LLWM1_2094)	-	2137531..2138022 (-)	492	WP_010906273.1	prolyl-tRNA synthetase associated domain-containing protein	-
LLWM1_RS10935 (LLWM1_2095)	-	2138101..2139084 (-)	984	Protein_2126	amino acid permease	-
LLWM1_RS10940 (LLWM1_2096)	-	2139173..2140063 (+)	891	WP_082225227.1	IS982-like element ISLll1 family transposase	-
LLWM1_RS10945 (LLWM1_2097)	-	2140066..2140602 (-)	537	Protein_2128	amino acid permease	-

Sequence

Protein

Download Length: 221 a.a. Molecular weight: 25664.87 Da Isoelectric Point: 8.8481

                                >NTDB_id=276406 LLWM1_RS10920 WP_004254535.1 2135745..2136410(+) (cclA/cilC) [Lactococcus lactis subsp. lactis strain WM1]

MDILFIFLIGSIFGSFFGLIVDRIPLRKSIIFGRSHCDSCQQLLAYRDLIPIFSQISSGSHCRYCKSKIPYLYVFLEFSS

ALIFVLAWVNYLKPSQFLLIILSLILSAFDYRQHSFPFVIWFIFALSFILIFPLSPLFYFWLILAVLAEKFNLRVGSGDF

LWFFTASFSLTFLNEMLLLQIACSLGIIYYLITKKRVEIAFIPFLTIAYLMLLFGHQILSP

Nucleotide

Download Length: 666 bp

                                >NTDB_id=276406 LLWM1_RS10920 WP_004254535.1 2135745..2136410(+) (cclA/cilC) [Lactococcus lactis subsp. lactis strain WM1]

ATGGACATTTTATTTATATTTTTAATTGGAAGTATTTTTGGCTCCTTTTTTGGCTTAATAGTTGACCGTATTCCACTAAG

AAAATCAATTATTTTTGGACGCTCACATTGTGATTCTTGTCAGCAACTTTTAGCCTATCGTGATCTAATTCCTATTTTTT

CTCAAATAAGCTCTGGCTCACATTGCCGTTATTGTAAAAGTAAAATTCCATATTTATATGTTTTTTTGGAGTTCTCATCA

GCTTTAATTTTTGTTTTAGCTTGGGTAAATTATCTTAAACCTAGTCAATTTTTACTGATTATTCTTTCACTAATTTTATC

TGCTTTTGATTATCGTCAGCACAGTTTTCCTTTTGTTATCTGGTTTATTTTTGCACTCAGTTTTATTTTAATATTTCCTC

TTTCTCCCCTTTTCTATTTTTGGCTTATTTTAGCCGTCTTAGCTGAAAAATTCAATTTAAGAGTTGGCAGCGGTGATTTT

TTATGGTTTTTTACCGCTTCATTTTCTCTAACTTTCTTAAACGAAATGCTGCTCCTTCAAATCGCTTGTTCACTTGGTAT

CATTTATTATCTAATCACAAAAAAACGAGTTGAAATTGCCTTCATCCCGTTTCTAACTATTGCATATCTAATGTTGCTTT

TTGGGCACCAAATTCTGTCACCGTAA

Domains

Predicted by InterProScan.

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(8-90)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure
AlphaFold DB	Q9CE22

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
cclA/cilC	Streptococcus mitis SK321	37.9	99.095	0.376
cclA/cilC	Streptococcus pneumoniae Rx1	38.14	97.285	0.371
cclA/cilC	Streptococcus pneumoniae D39	38.14	97.285	0.371
cclA/cilC	Streptococcus pneumoniae R6	38.14	97.285	0.371
cclA/cilC	Streptococcus pneumoniae TIGR4	37.674	97.285	0.367

Detailed information NTG0276406