Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   LLWM1_RS08695 Genome accession   NZ_CP032500
Coordinates   1722083..1723453 (-) Length   456 a.a.
NCBI ID   WP_003130363.1    Uniprot ID   -
Organism   Lactococcus lactis subsp. lactis strain WM1     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1717083..1728453
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LLWM1_RS08680 (LLWM1_1667) - 1718254..1719687 (-) 1434 WP_014570674.1 6-phospho-beta-glucosidase -
  LLWM1_RS08685 (LLWM1_1668) yidD 1719810..1720076 (-) 267 WP_010906087.1 membrane protein insertion efficiency factor YidD -
  LLWM1_RS08690 (LLWM1_1669) - 1720193..1721935 (-) 1743 WP_010906088.1 1-deoxy-D-xylulose-5-phosphate synthase -
  LLWM1_RS08695 (LLWM1_1670) ciaH 1722083..1723453 (-) 1371 WP_003130363.1 cell wall metabolism sensor histidine kinase WalK Regulator
  LLWM1_RS08700 (LLWM1_1671) ciaR 1723546..1724214 (-) 669 WP_021722129.1 response regulator transcription factor Regulator
  LLWM1_RS08705 (LLWM1_1672) - 1724392..1725366 (-) 975 WP_003130365.1 LacI family DNA-binding transcriptional regulator -
  LLWM1_RS08710 (LLWM1_1673) - 1725519..1727774 (-) 2256 WP_003130366.1 glycoside hydrolase family 65 protein -

Sequence

Protein


Download         Length: 456 a.a.        Molecular weight: 51300.85 Da        Isoelectric Point: 9.4537

>NTDB_id=276384 LLWM1_RS08695 WP_003130363.1 1722083..1723453(-) (ciaH) [Lactococcus lactis subsp. lactis strain WM1]
MKKIIKKVKSSAIVKNDGKNFLHFFLAFTVIFVALAVIIIQVMQLGMYRATDQNLHNLAQNRVFLIEAANNQLGMNNSQD
SGYYGPNNSVIFYDSEGKSFIPSAGSNANISTNFGMSLLQKTMKFNENQINTIQTVSVKNPYGDNWHYRYLTTSQFIITN
TDGTVTPVYAQIFSNVDQIQDAMSRAMWVIVTTMITFWLLSVIISLYLANWTLKPILAAYEKQKEFVENASHELRTPLAI
LQNRLELLFQKPTATIIDESENISESLSEVRNMRLLTSNLLNLARRDSGIRIEPEATTATYFENIFNSYEMLAENAGKKF
SGHLKLDGTINLDQALIKQLLTILFDNALKYTGDEGEISVDVQKNGGFLVFAVADNGEGISDEDKKKIFDRFFRVDKART
RQKGGLGLGLSLAKQIVEAYNGKITVEDNKPKGTKFIVRIRVDSTISNPAKIFQKL

Nucleotide


Download         Length: 1371 bp        

>NTDB_id=276384 LLWM1_RS08695 WP_003130363.1 1722083..1723453(-) (ciaH) [Lactococcus lactis subsp. lactis strain WM1]
TTGAAGAAAATAATTAAAAAAGTTAAATCTTCAGCTATTGTAAAAAATGATGGGAAAAATTTCCTTCATTTTTTTCTAGC
TTTTACAGTCATTTTTGTTGCTTTAGCCGTGATTATTATTCAAGTCATGCAATTAGGAATGTATCGAGCGACTGACCAAA
ATTTACACAATTTGGCTCAAAACCGAGTCTTTTTGATAGAAGCAGCGAATAATCAATTAGGAATGAATAATTCGCAAGAT
AGTGGCTATTACGGTCCCAATAATAGTGTGATTTTTTATGATTCAGAGGGTAAAAGTTTCATACCTTCAGCGGGTTCAAA
TGCAAATATAAGTACAAATTTTGGCATGAGCCTTCTGCAAAAAACAATGAAATTTAACGAAAATCAAATTAACACTATTC
AAACTGTTTCTGTAAAAAATCCTTATGGAGATAATTGGCACTATCGTTATCTGACAACATCACAATTTATTATTACAAAT
ACTGATGGAACAGTAACTCCGGTTTATGCACAAATTTTTTCAAATGTTGACCAAATTCAAGATGCCATGAGCCGAGCCAT
GTGGGTCATTGTGACAACAATGATTACTTTCTGGCTTCTGTCAGTAATTATTAGTCTATATCTTGCAAACTGGACATTAA
AACCAATTTTGGCCGCTTATGAAAAACAAAAAGAATTTGTTGAAAATGCTTCACATGAATTGAGAACACCTCTGGCAATC
TTGCAAAATCGTCTAGAATTACTTTTCCAAAAGCCAACAGCAACAATTATTGATGAATCAGAAAATATTTCTGAAAGTTT
ATCAGAAGTTCGTAATATGCGTTTATTAACAAGTAACTTACTGAACTTAGCTCGTCGAGATTCTGGAATCAGAATTGAGC
CAGAGGCGACTACGGCAACTTATTTTGAGAATATTTTTAATAGCTATGAAATGCTTGCTGAAAACGCAGGTAAAAAGTTT
TCAGGCCATTTGAAATTAGATGGAACGATTAATTTGGACCAAGCCCTGATTAAACAATTGCTAACCATCTTATTTGATAA
TGCTCTTAAATACACGGGTGATGAGGGTGAAATCTCTGTAGATGTTCAAAAAAATGGGGGATTCTTAGTTTTTGCTGTCG
CCGATAATGGTGAAGGAATTTCTGATGAAGATAAGAAAAAAATCTTTGACCGCTTTTTCCGAGTAGATAAAGCAAGAACG
CGTCAAAAAGGTGGCTTAGGTTTGGGTCTTTCTCTGGCCAAACAAATTGTTGAAGCTTACAATGGGAAGATTACAGTTGA
AGATAATAAACCTAAAGGTACAAAATTCATTGTTAGAATTCGTGTGGATAGCACAATTTCAAATCCTGCAAAAATTTTCC
AAAAGTTGTAA

Domains

Predicted by InterProScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(333-442)

His Kinase A (phospho-acceptor) domain (HisKA)

(223-289)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

48.837

94.298

0.461
  ciaH Streptococcus pneumoniae Rx1

44.321

98.465

0.436
  ciaH Streptococcus pneumoniae D39

44.321

98.465

0.436
  ciaH Streptococcus pneumoniae R6

44.321

98.465

0.436
  ciaH Streptococcus pneumoniae TIGR4

44.321

98.465

0.436

Multiple sequence alignment