Detailed information NTG0275925

Bioinformatically predicted

Overview

• Name: crp
• Type: Regulator
• Locus tag: C3V42_RS02255
• Genome accession: NZ_CP027235
• Coordinates: 466908..467585 (+)
• Length: 225 a.a.
• NCBI ID: WP_048954245.1
• Uniprot ID: A0A502KH34
• Organism: Haemophilus sp. oral taxon 036 strain F0629
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 461908..472585

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
C3V42_RS02215 (C3V42_02215)	mutM	461940..462752 (-)	813	WP_106013498.1	DNA-formamidopyrimidine glycosylase	-
C3V42_RS02220 (C3V42_02220)	rpmG	462824..462994 (-)	171	WP_005613503.1	50S ribosomal protein L33	-
C3V42_RS02225 (C3V42_02225)	rpmB	463006..463242 (-)	237	WP_005542826.1	50S ribosomal protein L28	-
C3V42_RS02230 (C3V42_02230)	radC	463456..464121 (-)	666	WP_106013499.1	DNA repair protein RadC	-
C3V42_RS02235 (C3V42_02235)	coaBC	464285..465487 (+)	1203	WP_106013500.1	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC	-
C3V42_RS02240 (C3V42_02240)	dut	465535..465990 (+)	456	WP_005631431.1	dUTP diphosphatase	-
C3V42_RS02245 (C3V42_02245)	slmA	465994..466650 (+)	657	WP_048954244.1	nucleoid occlusion factor SlmA	-
C3V42_RS02250 (C3V42_02250)	-	466672..466923 (+)	252	WP_005631427.1	YheU family protein	-
C3V42_RS02255 (C3V42_02255)	crp	466908..467585 (+)	678	WP_048954245.1	cAMP-activated global transcriptional regulator CRP	Regulator
C3V42_RS02260 (C3V42_02260)	rlmC	467951..469129 (-)	1179	WP_106013501.1	23S rRNA (uracil(747)-C(5))-methyltransferase RlmC	-
C3V42_RS02265 (C3V42_02265)	nagZ	469126..470178 (-)	1053	WP_106013502.1	beta-N-acetylhexosaminidase	-
C3V42_RS02270 (C3V42_02270)	-	470182..470532 (-)	351	WP_106013503.1	DUF1425 domain-containing protein	-
C3V42_RS02275 (C3V42_02275)	hinT	470532..470882 (-)	351	WP_065246130.1	purine nucleoside phosphoramidase	-

Sequence

Protein

• Length: 225 a.a.
• Molecular weight: 25245.96 Da
• Isoelectric Point: 6.6054

>NTDB_id=275925 C3V42_RS02255 WP_048954245.1 466908..467585(+) (crp) [Haemophilus sp. oral taxon 036 strain F0629]
MSNELTEIDEASVPPQEEESTTRDPILDWFLTHCHLHKYPAKSTLIHAGEDATTLYYVIKGTVMVSAKDDEGKEMILTYL
GAGQFFGEAGLFDEGSKRSAWVKTKTTCEIAEISYKKYRQLIQANPEILMFLTAQLARRLQNTSRQVSNLAFLDVAGRIA
QTLMNLAKQPEAMTHPDGMQIKITRQEIGQMVGCSRETVGRIIKMLEDQNLIHAHGKTIVVYGAR

Nucleotide

• Length: 678 bp

>NTDB_id=275925 C3V42_RS02255 WP_048954245.1 466908..467585(+) (crp) [Haemophilus sp. oral taxon 036 strain F0629]
ATGTCAAATGAATTAACCGAAATTGATGAAGCATCAGTTCCACCACAGGAAGAAGAATCAACGACTCGAGATCCTATTTT
AGACTGGTTTCTTACGCATTGCCACTTACACAAATATCCAGCAAAATCTACGCTAATTCATGCGGGAGAGGATGCAACTA
CACTTTATTATGTGATTAAAGGTACTGTAATGGTCTCTGCAAAAGATGATGAAGGAAAAGAAATGATCCTAACTTATCTA
GGAGCCGGACAATTCTTTGGAGAAGCAGGGCTATTTGATGAAGGCTCAAAACGTTCAGCATGGGTTAAAACAAAAACAAC
ATGTGAAATTGCTGAAATTTCCTATAAAAAATATCGTCAATTAATTCAAGCTAACCCAGAAATCTTAATGTTTTTAACCG
CACAATTGGCAAGACGTTTACAAAATACTTCACGCCAAGTGAGTAATTTAGCATTCTTAGATGTGGCAGGTCGTATTGCT
CAAACTCTAATGAACTTAGCTAAACAGCCTGAAGCAATGACACATCCTGATGGAATGCAAATCAAAATTACACGTCAAGA
AATTGGACAAATGGTTGGTTGTTCACGAGAAACTGTAGGACGTATTATTAAGATGTTAGAGGATCAAAATCTTATTCATG
CCCATGGAAAAACCATTGTTGTATATGGAGCAAGATAA

Domains

Predicted by InterproScan.

• Crp-like helix-turn-helix domain (HTH_Crp_2) (157-221)

• Cyclic nucleotide-binding domain (cNMP_binding) (37-125)

3D structure

• AlphaFold DB: A0A502KH34

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
crp	Haemophilus influenzae Rd KW20	94.667	100	0.947
crp	Vibrio cholerae strain A1552	75.248	89.778	0.676
crp	Acinetobacter baumannii D1279779	47.668	85.778	0.409