Detailed information NTG0275798

Bioinformatically predicted

Overview

• Name: comA
• Type: Machinery gene
• Locus tag: C2E19_RS21825
• Genome accession: NZ_CP027218
• Coordinates: 4768897..4771131 (-)
• Length: 744 a.a.
• NCBI ID: WP_129395041.1
• Uniprot ID: A0A481QXV1
• Organism: Pseudomonas sp. DTU12.3
• Function: ssDNA transport through the inner membrane (predicted from homology) DNA binding and uptake

Genomic Context

Location: 4763897..4776131

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
C2E19_RS21790 (C2E19_21830)	murB	4764276..4765295 (-)	1020	WP_129395036.1	UDP-N-acetylmuramate dehydrogenase	-
C2E19_RS21795 (C2E19_21835)	-	4765292..4765756 (-)	465	WP_129395037.1	low molecular weight protein-tyrosine-phosphatase	-
C2E19_RS21800 (C2E19_21840)	kdsB	4765756..4766520 (-)	765	WP_129395038.1	3-deoxy-manno-octulosonate cytidylyltransferase	-
C2E19_RS21805 (C2E19_21845)	-	4766517..4766702 (-)	186	WP_003174668.1	Trm112 family protein	-
C2E19_RS21810 (C2E19_21850)	lpxK	4766725..4767735 (-)	1011	WP_129395039.1	tetraacyldisaccharide 4'-kinase	-
C2E19_RS21815 (C2E19_21855)	-	4767735..4768163 (-)	429	WP_103307264.1	biopolymer transporter ExbD	-
C2E19_RS21820 (C2E19_21860)	exbB	4768160..4768795 (-)	636	WP_129395040.1	MotA/TolQ/ExbB proton channel family protein	Machinery gene
C2E19_RS21825 (C2E19_21865)	comA	4768897..4771131 (-)	2235	WP_129395041.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
C2E19_RS21830 (C2E19_21870)	-	4771267..4771785 (+)	519	WP_129395042.1	DUF2062 domain-containing protein	-
C2E19_RS21835 (C2E19_21875)	-	4771919..4772866 (-)	948	WP_129388636.1	transposase	-
C2E19_RS21840 (C2E19_21880)	-	4773110..4773889 (-)	780	WP_129395043.1	ABC transporter permease	-
C2E19_RS21845 (C2E19_21885)	-	4773886..4774818 (-)	933	WP_129395044.1	ABC transporter ATP-binding protein	-
C2E19_RS21850 (C2E19_21890)	-	4774943..4775566 (-)	624	WP_129395045.1	glutathione S-transferase family protein	-

Sequence

Protein

• Length: 744 a.a.
• Molecular weight: 81997.32 Da
• Isoelectric Point: 10.0917

>NTDB_id=275798 C2E19_RS21825 WP_129395041.1 4768897..4771131(-) (comA) [Pseudomonas sp. DTU12.3]
MRTGMMALAVGLLAPVFMPALPPVWLMLALPVAGLLVLQFRSYPLAFLLFGLTWTCVSAQWALDDSLPVALDGETRWLEG
RVVGLPQNGDGVVRFELADARSRHDKLPRLMRLAWYAGPAVNSGERWRLAVKLKRPVGLLNPDAFDYEAWLLAQRIGATG
TIKDGQRLAPARGAWRDSIRQRLLEVDAQGRGGALAALVLGDGSGLSREDWQVLQDTGTVHLLVISGQHIGLLAALMYGL
IAGLARLGIWPLRWPWLPWACGLALAAALGYGLLAGFDVPVQRACVMVALVLLWRLRFRHLGAWWPLLLAFNAVLLFDPL
ASLRPGFWLSFAAVAVLIFTFGARLGAWRWWQTWTRAQWLIAIGLCPVLLALNLPISVSGPLANLFAVPWVSLVVLPPAL
LGTLLLPVPYVGEGLLWLAGGLVDWLFRGLAVIAGQWPAWIGPSLPVWVWALGSLGALLLLLPRGVPMRVLGWPLLLILL
MPPRERLAEGMADIWQLDVGQGLAILIRTRHHTVLYDAGPRFGEFDLGERVVLPALHKLGVAKLDLMLLSHADADHAGGA
LVLMRGINLRRVVSGDPPGLPAALRAEECETGRQWQWDGVHFQLWQWSDAEDSNQRSCVLQIEANGERILLTGDIDTHAE
RSLLDSPLAVPTQWLQSPHHGSRSSSSMALLKTLQPESVLISRGHGNSFGHPHPTVLARYRKQGLRIYDSAEQGAIHLQL
GRFKPPWTMRQQRRFWRDPPAVAR

Nucleotide

• Length: 2235 bp

>NTDB_id=275798 C2E19_RS21825 WP_129395041.1 4768897..4771131(-) (comA) [Pseudomonas sp. DTU12.3]
ATGCGCACAGGGATGATGGCGCTGGCAGTCGGTTTGCTGGCCCCGGTTTTTATGCCGGCCTTACCGCCGGTCTGGTTGAT
GCTGGCGTTGCCGGTCGCAGGTTTGCTGGTGCTGCAATTTCGCAGCTATCCATTGGCCTTTCTGTTGTTTGGTTTGACGT
GGACGTGCGTCAGCGCGCAGTGGGCGCTGGACGATAGTTTGCCCGTCGCACTGGATGGCGAGACCCGTTGGCTGGAAGGA
CGAGTGGTCGGGCTGCCGCAGAACGGCGACGGCGTGGTGCGTTTCGAGTTGGCTGATGCACGCTCGCGTCACGACAAGCT
GCCGAGATTAATGCGTCTGGCGTGGTACGCCGGGCCTGCGGTCAACAGCGGCGAGCGTTGGCGACTGGCGGTGAAGCTGA
AACGTCCCGTGGGTTTGCTCAATCCGGACGCCTTCGATTATGAAGCGTGGCTGTTGGCGCAACGCATCGGTGCGACCGGG
ACGATCAAGGATGGCCAGCGTCTGGCGCCGGCTCGCGGCGCCTGGCGGGACAGCATCCGGCAGCGCTTGCTTGAGGTGGA
TGCGCAAGGGCGCGGCGGCGCACTGGCCGCGCTGGTGCTGGGGGACGGTTCGGGCCTCAGTCGCGAAGACTGGCAAGTTC
TGCAGGACACCGGCACTGTGCATTTGCTGGTTATTTCCGGCCAGCACATCGGTTTGCTGGCGGCGCTGATGTACGGATTG
ATTGCCGGGCTGGCGCGCCTAGGAATATGGCCATTGCGTTGGCCCTGGCTGCCGTGGGCCTGTGGTCTGGCATTGGCGGC
AGCGCTCGGTTACGGATTGCTCGCCGGGTTCGACGTGCCGGTGCAGCGCGCCTGCGTGATGGTCGCGCTGGTGCTGCTGT
GGCGTCTGCGTTTTCGCCATCTCGGTGCGTGGTGGCCATTGTTGCTCGCATTCAACGCGGTGCTGCTGTTCGATCCGCTG
GCGAGTCTGCGTCCCGGCTTCTGGTTGTCCTTCGCTGCGGTGGCGGTGCTGATTTTTACGTTTGGCGCGCGGCTGGGCGC
GTGGCGCTGGTGGCAGACCTGGACGCGGGCGCAATGGTTGATTGCGATCGGCCTGTGCCCGGTGTTGCTGGCGCTGAATT
TGCCGATCAGCGTGAGCGGACCGCTGGCCAATCTTTTCGCGGTGCCTTGGGTCAGTCTCGTGGTACTGCCTCCGGCATTG
CTCGGGACGCTGTTGTTGCCGGTGCCTTATGTCGGCGAAGGCTTGTTGTGGCTGGCCGGTGGCTTAGTCGATTGGCTGTT
TCGCGGCCTGGCTGTGATCGCCGGGCAATGGCCCGCTTGGATTGGTCCGTCATTGCCGGTGTGGGTCTGGGCGCTGGGCA
GTCTCGGCGCCTTGCTGTTGCTGTTGCCGCGCGGTGTGCCGATGCGTGTATTGGGCTGGCCGTTGCTGCTGATCCTGCTG
ATGCCGCCGCGCGAACGGCTCGCCGAAGGAATGGCCGACATCTGGCAACTCGATGTCGGCCAGGGCTTGGCGATCCTGAT
CCGTACCCGTCATCACACCGTGCTCTACGACGCAGGCCCGCGCTTTGGCGAGTTCGACCTCGGCGAGCGCGTGGTATTGC
CAGCCTTGCACAAGCTGGGCGTGGCAAAACTTGATCTGATGTTGCTCAGCCACGCGGACGCCGATCATGCCGGAGGCGCG
CTGGTGCTGATGCGCGGGATCAACCTGCGTCGGGTGGTCAGCGGCGATCCTCCGGGATTGCCCGCCGCATTGCGTGCCGA
AGAGTGTGAAACCGGCCGGCAATGGCAATGGGACGGCGTCCATTTTCAGCTCTGGCAATGGTCGGATGCCGAGGACAGCA
ATCAGCGTTCTTGCGTATTGCAGATCGAAGCCAATGGCGAGCGCATCCTGCTGACCGGCGACATCGATACCCACGCGGAA
CGTAGCCTGCTCGACAGCCCGCTGGCGGTGCCGACGCAATGGTTGCAATCGCCGCATCATGGCAGCCGCAGCTCTTCATC
CATGGCCCTGCTGAAAACGTTGCAGCCCGAGTCGGTGCTGATTTCCCGGGGCCACGGCAACTCCTTCGGCCATCCGCACC
CGACCGTGCTCGCGCGTTATCGCAAACAGGGTCTGCGCATTTATGACAGCGCTGAACAAGGCGCCATTCATCTGCAATTG
GGCCGCTTCAAACCGCCGTGGACGATGCGTCAACAGCGGCGTTTCTGGCGAGATCCGCCCGCAGTCGCCCGTTGA

Domains

Predicted by InterproScan.

• Metallo-beta-lactamase superfamily (Lactamase_B) (498-685)

• Competence protein (Competence) (198-464)

• Domain of unknown function (DUF4131) (DUF4131) (21-167)

3D structure

• AlphaFold DB: A0A481QXV1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA	Pseudomonas stutzeri DSM 10701	62.185	95.968	0.597
comA	Ralstonia pseudosolanacearum GMI1000	34.645	100	0.367