Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   SSA_RS09000 Genome accession   NC_009009
Coordinates   1831028..1832326 (-) Length   432 a.a.
NCBI ID   WP_011837400.1    Uniprot ID   -
Organism   Streptococcus sanguinis SK36     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1826028..1837326
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SSA_RS08990 (SSA_1834) hpf 1829742..1830284 (-) 543 WP_002903257.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  SSA_RS08995 (SSA_1835) - 1830366..1831031 (-) 666 WP_011837399.1 ComF family protein -
  SSA_RS09000 (SSA_1836) comFA/cflA 1831028..1832326 (-) 1299 WP_011837400.1 DEAD/DEAH box helicase Machinery gene
  SSA_RS09005 (SSA_1837) - 1832383..1833015 (+) 633 WP_011837401.1 YigZ family protein -
  SSA_RS09010 (SSA_1839) cysK 1833116..1834045 (+) 930 WP_002893488.1 cysteine synthase A -
  SSA_RS09015 (SSA_1840) - 1834150..1834512 (-) 363 WP_002901252.1 S1 RNA-binding domain-containing protein -
  SSA_RS09020 (SSA_1841) - 1834512..1835912 (-) 1401 WP_011837402.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  SSA_RS09025 (SSA_1842) - 1835952..1836584 (-) 633 WP_002893493.1 response regulator transcription factor -

Sequence

Protein


Download         Length: 432 a.a.        Molecular weight: 49438.19 Da        Isoelectric Point: 8.5344

>NTDB_id=27534 SSA_RS09000 WP_011837400.1 1831028..1832326(-) (comFA/cflA) [Streptococcus sanguinis SK36]
MLELQDCLGRIFTESQLESSLRAQAKEIPSIREEKGKLCCGRCNSLIERENQLPVGAYYCRECLILGQVRSDQKLYYFPQ
EDFPKNQVLKWQGQLTEFQGKVSKGLLDALEKRQNTLVHAVTGAGKTEMIYQVLARVIDRGGSVCLASPRIDVCLELYRR
LKEDFSCEIALLHGESEAYFRSPFVIATTHQLLKFYRAFDLLIVDEVDAFPYVDNPILYHAVERSVKEDATTIFLTATST
DELDKRVQKGELKRLSLPRRFHGNPLTIPQKVWLSDFQKYLQKKKIAPKLLNYIQKQRKTQFPLLIFAAEIQRGEDVAQA
LQIALPDEKLAFVASTTENRLEIVEQFRRKEITILVTTTILERGVTFPGVDVFVLEANHRLFSRSALVQISGRVGRSMNR
PTGQLLFFHDGTTLAMEKAIREMRDMNKEAGL

Nucleotide


Download         Length: 1299 bp        

>NTDB_id=27534 SSA_RS09000 WP_011837400.1 1831028..1832326(-) (comFA/cflA) [Streptococcus sanguinis SK36]
ATGTTAGAGTTACAAGATTGTTTAGGACGGATATTTACAGAAAGTCAGTTAGAGTCTAGCTTGCGAGCACAAGCAAAAGA
AATTCCCAGTATCCGAGAAGAAAAAGGCAAGCTCTGCTGCGGACGCTGCAACAGCTTGATTGAACGAGAAAATCAACTGC
CGGTTGGAGCTTATTATTGCAGAGAATGCTTAATCTTGGGTCAGGTACGGAGTGACCAAAAACTCTACTATTTTCCCCAA
GAGGATTTTCCTAAGAATCAGGTGCTTAAATGGCAGGGGCAACTGACAGAGTTTCAAGGAAAGGTTTCCAAAGGATTACT
TGATGCGCTAGAGAAAAGGCAGAATACGTTAGTGCATGCTGTTACTGGCGCTGGAAAAACAGAAATGATTTACCAAGTGC
TTGCAAGGGTTATTGATAGAGGAGGTTCTGTCTGTTTGGCCAGTCCGCGGATTGATGTTTGTTTAGAGCTTTATCGGCGC
CTTAAAGAAGATTTTTCTTGTGAAATAGCTCTTCTGCATGGGGAGTCAGAAGCTTATTTTCGCAGCCCCTTTGTAATTGC
CACCACCCACCAGCTCTTAAAATTTTATCGGGCTTTTGATTTGTTGATTGTGGACGAGGTAGACGCCTTTCCTTATGTGG
ATAATCCCATACTGTATCACGCTGTAGAGCGTTCAGTTAAAGAGGATGCTACAACTATTTTTCTGACAGCCACTTCCACG
GATGAACTGGATAAAAGAGTTCAAAAAGGTGAGCTGAAACGCCTGAGTCTTCCCAGAAGATTTCATGGTAATCCCTTGAC
CATCCCTCAGAAAGTTTGGTTATCTGATTTTCAAAAGTATCTTCAGAAGAAGAAAATAGCACCTAAACTTTTGAACTATA
TACAAAAACAGAGAAAGACTCAATTTCCTCTCTTGATATTTGCTGCAGAAATTCAAAGAGGAGAGGATGTTGCTCAGGCT
TTGCAGATAGCTCTGCCTGATGAAAAGTTGGCTTTTGTCGCCTCCACAACAGAAAATCGTCTAGAGATTGTCGAGCAGTT
TCGTCGCAAGGAGATTACTATTTTGGTGACAACGACTATCTTAGAGCGTGGAGTAACCTTTCCTGGTGTAGATGTTTTTG
TCTTGGAAGCCAATCATCGCCTGTTCAGTCGTAGTGCTCTGGTTCAGATTTCAGGCCGAGTTGGCCGTAGTATGAATAGA
CCGACTGGACAGTTGCTATTTTTTCATGATGGGACTACCCTTGCTATGGAAAAGGCAATTCGGGAAATGAGGGATATGAA
TAAGGAGGCAGGATTATGA

Domains

Predicted by InterproScan.

Helicase conserved C-terminal domain (Helicase_C)

(290-396)

DEAD/DEAH box helicase (DEAD)

(109-244)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus pneumoniae Rx1

70.492

98.843

0.697
  comFA/cflA Streptococcus pneumoniae D39

70.492

98.843

0.697
  comFA/cflA Streptococcus pneumoniae R6

70.492

98.843

0.697
  comFA/cflA Streptococcus pneumoniae TIGR4

70.258

98.843

0.694
  comFA/cflA Streptococcus mitis NCTC 12261

70.118

98.38

0.69
  comFA/cflA Streptococcus mitis SK321

69.176

98.38

0.681
  comFA Lactococcus lactis subsp. cremoris KW2

54.02

92.13

0.498
  comFA Latilactobacillus sakei subsp. sakei 23K

38.228

99.306

0.38

Multiple sequence alignment