Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   D3W53_RS01870 Genome accession   NZ_CP032237
Coordinates   391386..392018 (-) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain ECCWS199     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 386386..397018
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  D3W53_RS01845 (D3W53_01875) yhfG 386518..386685 (+) 168 WP_000736860.1 YhfG family protein -
  D3W53_RS01850 (D3W53_01880) fic 386675..387277 (+) 603 WP_001280624.1 putative adenosine monophosphate-protein transferase Fic -
  D3W53_RS01855 (D3W53_01885) pabA 387309..387872 (+) 564 WP_000601847.1 aminodeoxychorismate synthase component 2 -
  D3W53_RS01860 (D3W53_01890) argD 387958..389178 (+) 1221 WP_000963792.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  D3W53_RS01865 (D3W53_01895) yhfK 389245..391335 (-) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  D3W53_RS01870 (D3W53_01900) crp 391386..392018 (-) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  D3W53_RS01880 (D3W53_01910) yhfA 392320..392724 (+) 405 WP_001148908.1 OsmC family protein -
  D3W53_RS01885 (D3W53_01915) prkB 392779..393648 (-) 870 WP_001274680.1 phosphoribulokinase -
  D3W53_RS01890 (D3W53_01920) yheU 393702..393920 (-) 219 WP_000907085.1 YheU family protein -
  D3W53_RS01895 (D3W53_01925) yheT 393914..394936 (-) 1023 WP_000057356.1 hydrolase -
  D3W53_RS01900 (D3W53_01930) yheS 394936..396849 (-) 1914 WP_000634798.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=275079 D3W53_RS01870 WP_000242755.1 391386..392018(-) (crp) [Escherichia coli strain ECCWS199]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=275079 D3W53_RS01870 WP_000242755.1 391386..392018(-) (crp) [Escherichia coli strain ECCWS199]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCAGACGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTTGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467