Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   D2195_RS16690 Genome accession   NZ_CP032078
Coordinates   3454021..3454677 (-) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain CT30     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 3449021..3459677
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  D2195_RS16660 (D2195_17845) yecA 3450272..3450937 (-) 666 WP_000847885.1 UPF0149 family protein YecA -
  D2195_RS16680 (D2195_17865) pgsA 3451587..3452135 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  D2195_RS16685 (D2195_17870) uvrC 3452192..3454024 (-) 1833 WP_001283427.1 excinuclease ABC subunit UvrC Machinery gene
  D2195_RS16690 (D2195_17875) letA 3454021..3454677 (-) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  D2195_RS26660 (D2195_17880) - 3454819..3454935 (+) 117 WP_001302039.1 hypothetical protein -
  D2195_RS16695 yecU 3454973..3455149 (+) 177 WP_000590344.1 protein YecU -
  D2195_RS16700 (D2195_17885) yecF 3455136..3455360 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  D2195_RS16705 (D2195_17890) sdiA 3455427..3456149 (-) 723 WP_001154273.1 transcriptional regulator SdiA -
  D2195_RS16710 (D2195_17895) tcyN 3456379..3457131 (-) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  D2195_RS16715 (D2195_17900) tcyL 3457128..3457796 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  D2195_RS16720 (D2195_17905) dcyD 3457811..3458797 (-) 987 WP_001128215.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=274453 D2195_RS16690 WP_000611335.1 3454021..3454677(-) (letA) [Escherichia coli strain CT30]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=274453 D2195_RS16690 WP_000611335.1 3454021..3454677(-) (letA) [Escherichia coli strain CT30]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486