Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   D2195_RS16685 Genome accession   NZ_CP032078
Coordinates   3452192..3454024 (-) Length   610 a.a.
NCBI ID   WP_001283427.1    Uniprot ID   -
Organism   Escherichia coli strain CT30     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 3447192..3459024
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  D2195_RS16635 (D2195_17815) azuC 3447203..3447289 (-) 87 WP_010723106.1 stress response protein AzuC -
  D2195_RS16640 (D2195_17825) yecR 3447552..3447875 (+) 324 WP_001237876.1 YecR-like lipofamily protein -
  D2195_RS16645 (D2195_17830) ftnA 3448047..3448544 (+) 498 WP_000917208.1 non-heme ferritin -
  D2195_RS16650 (D2195_17835) yecH 3448582..3448821 (-) 240 WP_000377224.1 YecH family metal-binding protein -
  D2195_RS16655 (D2195_17840) tyrP 3449011..3450222 (+) 1212 WP_000797555.1 tyrosine transporter TyrP -
  D2195_RS16660 (D2195_17845) yecA 3450272..3450937 (-) 666 WP_000847885.1 UPF0149 family protein YecA -
  D2195_RS16680 (D2195_17865) pgsA 3451587..3452135 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  D2195_RS16685 (D2195_17870) uvrC 3452192..3454024 (-) 1833 WP_001283427.1 excinuclease ABC subunit UvrC Machinery gene
  D2195_RS16690 (D2195_17875) letA 3454021..3454677 (-) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  D2195_RS26660 (D2195_17880) - 3454819..3454935 (+) 117 WP_001302039.1 hypothetical protein -
  D2195_RS16695 yecU 3454973..3455149 (+) 177 WP_000590344.1 protein YecU -
  D2195_RS16700 (D2195_17885) yecF 3455136..3455360 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  D2195_RS16705 (D2195_17890) sdiA 3455427..3456149 (-) 723 WP_001154273.1 transcriptional regulator SdiA -
  D2195_RS16710 (D2195_17895) tcyN 3456379..3457131 (-) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  D2195_RS16715 (D2195_17900) tcyL 3457128..3457796 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  D2195_RS16720 (D2195_17905) dcyD 3457811..3458797 (-) 987 WP_001128215.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 610 a.a.        Molecular weight: 68202.06 Da        Isoelectric Point: 9.3685

>NTDB_id=274452 D2195_RS16685 WP_001283427.1 3452192..3454024(-) (uvrC) [Escherichia coli strain CT30]
MSDQFDAKAFLKTVTSQPGVYRMYDAGGTVIYVGKAKDLKKRLSSYFRSNLASRKTEALVAQIQQIDVTVTHTETEALLL
EHNYIKLYQPRYNVLLRDDKSYPFIFLSGDTHPRLAMHRGAKHAKGEYFGPFPNGYAVRETLALLQKIFPIRQCENSVYR
NRSRPCLQYQIGRCLGPCVEGLVSEEEYAQQVEYVRLFLSGKDDQVLTQLISRMETASQNLEFEEAARIRDQIQAVRRVT
EKQFVSNTGDDLDVIGVAFDAGMACVHVLFIRQGKVLGSRSYFPKVPGGTELSEVVETFVGQFYLQGSQMRTLPGEILLD
FNLSDKTLLADSLSELAGRKINVQTKPRGDRARYLKLARTNAATALTSKLSQQSTVHQRLTALASVLKLPEVKRMECFDI
SHTMGEQTVASCVVFDANGPLRAEYRRYNITGITPGDDYAAMNQVLRRRYGKAIDESKIPDVILIDGGKGQLAQAKNVFA
ELDVSWDKNHPLLLGVAKGADRKAGLETLFFEPEGEGFSLPPDSPALHVIQHIRDESHDHAIGGHRKKRAKVKNTSSLET
IEGVGPKRRQMLLKYMGGLQGLRNASVEEIAKVPGISQGLAEKIFWSLKH

Nucleotide


Download         Length: 1833 bp        

>NTDB_id=274452 D2195_RS16685 WP_001283427.1 3452192..3454024(-) (uvrC) [Escherichia coli strain CT30]
GTGAGTGATCAGTTTGACGCAAAAGCGTTTTTAAAAACCGTAACCAGCCAGCCAGGCGTTTATCGCATGTACGATGCTGG
TGGTACGGTTATCTATGTCGGCAAAGCGAAAGACCTGAAAAAACGGCTTTCCAGCTATTTCCGTAGCAACCTCGCTTCGC
GCAAAACCGAAGCGCTGGTCGCCCAGATCCAGCAAATTGATGTAACGGTTACTCATACAGAAACCGAAGCGCTGTTGCTG
GAACACAACTACATCAAACTCTATCAGCCGCGTTACAACGTTTTGCTACGCGATGATAAATCTTATCCCTTTATCTTCCT
GAGTGGCGATACCCATCCGCGTCTGGCGATGCATCGTGGTGCGAAGCATGCTAAAGGTGAATATTTCGGCCCGTTCCCGA
ATGGCTATGCCGTACGTGAAACACTGGCGCTACTGCAAAAGATATTCCCCATTCGCCAGTGCGAAAATAGTGTTTATCGC
AATCGCTCGCGTCCGTGTCTGCAATATCAGATAGGGCGCTGTCTGGGACCGTGCGTTGAAGGACTGGTGAGTGAAGAAGA
ATACGCTCAGCAGGTCGAGTATGTGCGCCTGTTTTTGTCTGGCAAAGATGATCAGGTGCTTACGCAACTCATTAGTCGTA
TGGAAACTGCCAGCCAGAATCTGGAGTTTGAAGAAGCGGCACGTATTCGCGACCAAATTCAGGCGGTGCGACGCGTCACC
GAAAAACAGTTTGTGTCCAATACCGGCGACGACCTCGACGTTATTGGTGTGGCGTTCGATGCGGGCATGGCTTGTGTCCA
CGTATTGTTCATTCGTCAGGGTAAAGTGCTCGGCAGCCGCAGCTATTTCCCGAAAGTGCCTGGCGGTACGGAACTGAGCG
AGGTGGTGGAAACCTTCGTAGGTCAGTTCTATTTACAAGGCAGCCAGATGCGCACCTTACCGGGTGAGATCCTGCTCGAT
TTTAATCTTAGCGATAAAACGCTGCTCGCCGATTCCCTTTCAGAACTGGCGGGACGCAAGATTAATGTTCAAACCAAACC
TCGCGGCGATCGGGCGCGTTATCTGAAACTCGCGCGCACCAATGCGGCGACGGCATTAACCAGCAAACTTTCGCAGCAAT
CTACCGTTCACCAGCGACTGACCGCGCTTGCCAGCGTGTTGAAATTGCCGGAAGTGAAGCGGATGGAATGCTTTGACATC
AGCCATACCATGGGGGAACAAACCGTCGCTTCCTGTGTGGTGTTTGATGCTAACGGCCCGCTGCGTGCGGAGTATCGACG
CTATAACATTACTGGCATCACGCCGGGCGATGATTATGCGGCGATGAATCAGGTGCTGCGTCGGCGTTATGGTAAAGCCA
TCGACGAGAGTAAGATCCCGGATGTGATCCTTATCGACGGCGGCAAAGGCCAACTTGCGCAGGCGAAAAATGTTTTCGCC
GAACTGGATGTCTCATGGGATAAAAATCATCCGCTGCTACTAGGCGTTGCCAAAGGAGCAGATCGTAAGGCTGGGCTGGA
AACGCTGTTCTTTGAGCCGGAAGGTGAGGGATTCAGTTTGCCGCCAGATTCTCCCGCACTGCATGTTATCCAGCATATTC
GCGATGAATCACACGATCACGCGATTGGCGGGCACCGTAAAAAACGGGCGAAGGTCAAAAATACCAGTTCCCTGGAAACC
ATTGAAGGCGTCGGGCCAAAACGTCGGCAAATGTTGTTGAAATATATGGGCGGTTTGCAAGGTTTACGTAACGCCAGCGT
CGAGGAAATTGCAAAAGTGCCGGGTATTTCGCAAGGTCTGGCAGAAAAGATCTTCTGGTCGTTGAAACATTGA

Domains

Predicted by InterProScan.

UvrB/uvrC motif (UVR)

(205-237)

Helix-hairpin-helix domain (HHH_5)

(558-609)

GIY-YIG catalytic domain (GIY-YIG)

(18-93)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-542)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

38.056

99.508

0.379
  uvrC Streptococcus pneumoniae R6

37.727

99.508

0.375
  uvrC Streptococcus pneumoniae D39

37.727

99.508

0.375