Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   D2J89_RS08340 Genome accession   NZ_CP032066
Coordinates   1740740..1741330 (+) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain E166     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1735740..1746330
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  D2J89_RS08310 (D2J89_09005) yidF 1735859..1736356 (+) 498 WP_000148034.1 radical SAM protein -
  D2J89_RS08315 (D2J89_09010) emrD 1736364..1737548 (-) 1185 WP_001696327.1 multidrug efflux MFS transporter EmrD -
  D2J89_RS25620 ysdE 1737630..1737704 (+) 75 WP_211180519.1 protein YsdE -
  D2J89_RS08320 (D2J89_09020) tisB 1737828..1737917 (-) 90 WP_000060506.1 type I toxin-antitoxin system toxin TisB -
  D2J89_RS08325 (D2J89_09040) ivbL 1738481..1738579 (+) 99 WP_001312198.1 ilvB operon leader peptide IvbL -
  D2J89_RS08330 (D2J89_09045) ilvB 1738685..1740373 (+) 1689 WP_000168476.1 acetolactate synthase large subunit -
  D2J89_RS08335 (D2J89_09050) ilvN 1740377..1740667 (+) 291 WP_001181706.1 acetolactate synthase small subunit -
  D2J89_RS08340 (D2J89_09055) letA 1740740..1741330 (+) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  D2J89_RS08345 (D2J89_09060) uhpB 1741330..1742832 (+) 1503 WP_001318135.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  D2J89_RS08350 (D2J89_09065) uhpC 1742842..1744161 (+) 1320 WP_001696326.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  D2J89_RS08355 (D2J89_09070) uhpT 1744417..1745808 (+) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=274268 D2J89_RS08340 WP_000633668.1 1740740..1741330(+) (letA) [Escherichia coli strain E166]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=274268 D2J89_RS08340 WP_000633668.1 1740740..1741330(+) (letA) [Escherichia coli strain E166]
ATGATCACCGTTGCCCTTATAGACGATCACCTTATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCTGATATCTCCGGTCTGGAGCTTCTAAGCCAGCTGCCGAAAGGCATGGCGACAATTATGCTCTCCGTT
CACGACAGTCCGGCGCTGGTTGAGCAGGCGCTTAACGCCGGGGCGCGCGGCTTTCTCTCCAAACGCTGTAGCCCGGATGA
ACTCATTGCTGCGGTGCATACGGTTGCCACTGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GCCAGGACCCGCTAACCAAACGCGAACGCCAGGTGGCAGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCCGCC
GAACTGGGCTTGTCACCGAAAACGGTACACGTCCATCGCGCCAATCTGATGGAAAAACTGGGCGTCAGTAACGACGTTGA
ACTGGCGCGCCGTATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378