Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilU   Type   Machinery gene
Locus tag   NMCC_RS00265 Genome accession   NC_010120
Coordinates   51018..52244 (-) Length   408 a.a.
NCBI ID   WP_002249603.1    Uniprot ID   -
Organism   Neisseria meningitidis 053442     
Function   mediate the depolymerization of the type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 46018..57244
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NMCC_RS00260 (NMCC_0050) yccS 48750..50900 (-) 2151 WP_002246572.1 YccS family putative transporter -
  NMCC_RS00265 (NMCC_0051) pilU 51018..52244 (-) 1227 WP_002249603.1 PilT/PilU family type 4a pilus ATPase Machinery gene
  NMCC_RS00270 (NMCC_0052) pilT 52407..53450 (-) 1044 WP_002226887.1 type IV pilus twitching motility protein PilT Machinery gene
  NMCC_RS00275 (NMCC_0053) - 53570..54256 (+) 687 WP_012221118.1 YggS family pyridoxal phosphate-dependent enzyme -
  NMCC_RS00280 (NMCC_0054) - 54256..54663 (+) 408 WP_002221801.1 hypothetical protein -
  NMCC_RS00285 (NMCC_0055) proC 54694..55503 (+) 810 WP_228475988.1 pyrroline-5-carboxylate reductase -
  NMCC_RS00290 (NMCC_0056) dksA 55650..56066 (+) 417 WP_002215267.1 RNA polymerase-binding protein DksA -

Sequence

Protein


Download         Length: 408 a.a.        Molecular weight: 45732.31 Da        Isoelectric Point: 6.8200

>NTDB_id=27418 NMCC_RS00265 WP_002249603.1 51018..52244(-) (pilU) [Neisseria meningitidis 053442]
MNTDNLHDILDEMVQVYSQKKQSRSETPAEIGAHFHPLLDRLCETAEAQNASDILISKGFPPSLKINSALTPQPQKALTG
EETAAIAASTMNAEQSEIFRRDGEINYSVQSRSGTRYRANAYHSQGSAGLVLRRINHVIPQMQELGLPEKLKDLAVAPRG
LLIIVGPTGSGKSTTMATMLEHRNKTLPSHIVTIEDPIEFIYKPRRCIFTQREIGVDTINWQTAVQNAMRQSPDVVCIGE
VRSRESMEYAMQLAQTGHLCIFTLHANTAPQSLERILNFYPKEQHNQILIDIALNLTGIICQRLALKQDKTGRTAVVDLL
INTPAIQDFILKGDLMNISKIMETAKTDGMQTMDQNLFELYRHGIISYEEALRQSVSANNLRLHIQLHKEGKTPELLYDR
INDLNLVS

Nucleotide


Download         Length: 1227 bp        

>NTDB_id=27418 NMCC_RS00265 WP_002249603.1 51018..52244(-) (pilU) [Neisseria meningitidis 053442]
ATGAATACCGATAACCTGCACGACATCTTGGACGAAATGGTTCAAGTGTATTCTCAAAAAAAACAAAGCCGATCCGAAAC
CCCGGCCGAAATCGGCGCACACTTCCACCCGCTGCTCGACCGCCTGTGCGAAACCGCAGAAGCACAAAACGCGTCCGACA
TCCTTATCAGCAAAGGATTCCCGCCCTCGTTGAAAATCAACAGCGCATTAACCCCGCAGCCGCAAAAGGCGCTGACGGGC
GAGGAAACCGCCGCCATCGCCGCATCGACGATGAACGCCGAACAATCGGAAATATTCCGGCGCGACGGCGAAATCAACTA
CTCCGTCCAGTCGCGCAGCGGCACGCGCTACCGCGCCAACGCCTACCACAGCCAAGGCAGCGCAGGTTTGGTTTTGCGGC
GCATCAACCACGTCATCCCGCAAATGCAGGAATTGGGCCTGCCCGAAAAACTCAAAGACCTCGCCGTCGCACCGCGCGGG
CTGCTGATTATCGTCGGGCCTACCGGTTCGGGCAAATCCACCACGATGGCGACTATGCTCGAACACCGCAACAAAACCCT
GCCCAGCCATATCGTTACCATCGAAGACCCGATTGAGTTTATCTACAAACCGCGCCGCTGCATCTTTACCCAGCGCGAAA
TCGGCGTCGACACCATAAACTGGCAGACGGCGGTACAAAACGCTATGCGCCAGTCCCCCGACGTGGTCTGCATCGGCGAA
GTCCGCAGCAGGGAAAGTATGGAATACGCGATGCAGCTCGCCCAAACCGGCCACCTGTGCATTTTTACGCTCCACGCCAA
CACCGCGCCGCAGTCGCTCGAACGCATACTCAACTTCTACCCCAAAGAACAGCACAACCAAATACTGATCGACATCGCCC
TCAACCTGACCGGCATCATCTGCCAACGCCTCGCCCTCAAACAAGACAAAACGGGCAGGACGGCGGTTGTCGACTTGCTC
ATCAACACGCCCGCCATCCAAGACTTCATCCTGAAGGGCGACCTGATGAACATCAGTAAAATCATGGAAACCGCCAAAAC
CGACGGAATGCAGACGATGGATCAAAACCTTTTCGAACTGTACCGTCACGGCATCATCAGTTACGAAGAAGCCCTGCGCC
AGTCCGTTTCCGCCAACAACCTGCGATTGCACATCCAACTGCACAAAGAAGGCAAAACGCCCGAACTCCTTTACGACAGG
ATTAACGACCTCAACCTCGTTTCCTAA

Domains

Predicted by InterProScan.

Type II/IV secretion system protein (T2SSE)

(49-305)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilU Acinetobacter baylyi ADP1

44.598

88.48

0.395
  pilU Pseudomonas stutzeri DSM 10701

44.663

87.255

0.39
  pilU Vibrio cholerae strain A1552

46.429

82.353

0.382

Multiple sequence alignment