Detailed information NTG0273950

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: RK64_RS00205
• Genome accession: NZ_CP026962
• Coordinates: 37752..38639 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain FDAARGOS_6
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 32752..43639

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RK64_RS00170 (RK64_00170)	-	32771..32863 (+)	93	WP_010956583.1	hypothetical protein	-
RK64_RS00175 (RK64_00175)	-	32971..33468 (-)	498	WP_001065268.1	glutathione peroxidase	-
RK64_RS00180 (RK64_00180)	-	33478..33738 (-)	261	WP_001789910.1	hypothetical protein	-
RK64_RS00190 (RK64_00190)	-	34120..34233 (-)	114	WP_011447078.1	hypothetical protein	-
RK64_RS00195 (RK64_00195)	-	34892..36892 (-)	2001	WP_000776751.1	ABC transporter permease	-
RK64_RS00200 (RK64_00200)	-	36889..37644 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
RK64_RS00205 (RK64_00205)	braS	37752..38639 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
RK64_RS00210 (RK64_00210)	braR	38650..39315 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
RK64_RS00215 (RK64_00215)	-	39341..39541 (-)	201	WP_000604728.1	hypothetical protein	-
RK64_RS00220 (RK64_00220)	-	39739..41163 (+)	1425	WP_000953744.1	alkaline phosphatase	-
RK64_RS14500 (RK64_00225)	-	41223..41324 (-)	102	WP_000731972.1	SE2200 family small protein	-
RK64_RS00230 (RK64_00230)	-	41446..41901 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
RK64_RS00235 (RK64_00235)	-	42146..42907 (-)	762	WP_000323455.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=273950 RK64_RS00205 WP_000143419.1 37752..38639(-) (braS) [Staphylococcus aureus strain FDAARGOS_6]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=273950 RK64_RS00205 WP_000143419.1 37752..38639(-) (braS) [Staphylococcus aureus strain FDAARGOS_6]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997