Detailed information
Bioinformatically predicted
Overview
| Name | vraR | Type | Regulator |
| Locus tag | RK73_RS07205 | Genome accession | NZ_CP026960 |
| Coordinates | 1356590..1357219 (-) | Length | 209 a.a. |
| NCBI ID | WP_000153530.1 | Uniprot ID | D9IFM7 |
| Organism | Staphylococcus aureus strain FDAARGOS_15 | ||
| Function | repress expression of competence genes (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 1349511..1382539 | 1356590..1357219 | within | 0 |
Gene organization within MGE regions
Location: 1349511..1382539
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| RK73_RS07165 (RK73_07165) | - | 1349511..1350557 (+) | 1047 | WP_001145732.1 | tyrosine-type recombinase/integrase | - |
| RK73_RS07170 (RK73_07170) | yfkAB | 1350602..1351747 (+) | 1146 | WP_001245448.1 | radical SAM/CxCxxxxC motif protein YfkAB | - |
| RK73_RS07175 (RK73_07175) | - | 1352007..1352537 (-) | 531 | WP_000184383.1 | acyl-CoA thioesterase | - |
| RK73_RS07180 (RK73_07180) | - | 1352627..1353883 (-) | 1257 | WP_001795438.1 | aminopeptidase | - |
| RK73_RS07185 (RK73_07185) | - | 1353886..1354086 (-) | 201 | WP_000180461.1 | DUF1128 family protein | - |
| RK73_RS07190 (RK73_07190) | - | 1354233..1354697 (+) | 465 | WP_000228666.1 | low molecular weight protein-tyrosine-phosphatase | - |
| RK73_RS07195 (RK73_07195) | - | 1354704..1354979 (+) | 276 | WP_000428172.1 | YtxH domain-containing protein | - |
| RK73_RS07200 (RK73_07200) | - | 1355257..1356474 (+) | 1218 | WP_000037075.1 | YihY/virulence factor BrkB family protein | - |
| RK73_RS07205 (RK73_07205) | vraR | 1356590..1357219 (-) | 630 | WP_000153530.1 | two-component system response regulator VraR | Regulator |
| RK73_RS07210 (RK73_07210) | vraS | 1357209..1358252 (-) | 1044 | WP_001017131.1 | sensor histidine kinase | Regulator |
| RK73_RS07215 (RK73_07215) | liaF | 1358249..1358950 (-) | 702 | WP_000149064.1 | cell wall-active antibiotics response protein LiaF | - |
| RK73_RS07220 (RK73_07220) | - | 1358965..1359351 (-) | 387 | WP_001110179.1 | hypothetical protein | - |
| RK73_RS07225 (RK73_07225) | map | 1359568..1360326 (-) | 759 | WP_000636142.1 | type I methionyl aminopeptidase | - |
| RK73_RS07240 (RK73_07240) | - | 1360854..1361840 (+) | 987 | WP_000999713.1 | FUSC family protein | - |
| RK73_RS07250 (RK73_07250) | - | 1362271..1362684 (-) | 414 | WP_001549145.1 | hypothetical protein | - |
| RK73_RS07255 (RK73_07255) | - | 1362713..1362823 (-) | 111 | WP_001790257.1 | hypothetical protein | - |
| RK73_RS07260 (RK73_07260) | - | 1362909..1363640 (-) | 732 | WP_000544969.1 | type 1 glutamine amidotransferase | - |
| RK73_RS07265 (RK73_07265) | murT | 1363642..1364955 (-) | 1314 | WP_001250336.1 | lipid II isoglutaminyl synthase subunit MurT | - |
| RK73_RS07270 (RK73_07270) | ftnA | 1365247..1365747 (+) | 501 | WP_000949467.1 | H-type ferritin FtnA | - |
| RK73_RS07275 (RK73_07275) | - | 1365829..1365921 (-) | 93 | WP_001790679.1 | hypothetical protein | - |
| RK73_RS07280 (RK73_07280) | - | 1366136..1366690 (+) | 555 | WP_000613733.1 | 3'-5' exonuclease | - |
| RK73_RS07285 (RK73_07285) | dinB | 1366758..1367828 (-) | 1071 | WP_000140176.1 | DNA polymerase IV | - |
| RK73_RS07290 (RK73_07290) | - | 1368075..1368605 (-) | 531 | WP_000548781.1 | DUF3267 domain-containing protein | - |
| RK73_RS07295 (RK73_07295) | rlmD | 1368775..1370136 (-) | 1362 | WP_001147868.1 | 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD | - |
| RK73_RS07300 (RK73_07300) | - | 1370217..1371164 (-) | 948 | WP_001231451.1 | diacylglycerol kinase | - |
| RK73_RS07310 (RK73_07310) | - | 1371747..1371893 (-) | 147 | WP_001797372.1 | hypothetical protein | - |
| RK73_RS07315 (RK73_07315) | gatB | 1371933..1373360 (-) | 1428 | WP_000545370.1 | Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB | - |
| RK73_RS07320 (RK73_07320) | gatA | 1373373..1374830 (-) | 1458 | WP_000027928.1 | Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA | - |
| RK73_RS07325 (RK73_07325) | gatC | 1374832..1375134 (-) | 303 | WP_000170162.1 | Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC | - |
| RK73_RS07330 (RK73_07330) | putP | 1375501..1377039 (+) | 1539 | WP_000957020.1 | sodium/proline symporter PutP | - |
| RK73_RS07335 (RK73_07335) | - | 1377128..1378327 (-) | 1200 | WP_000831698.1 | CamS family sex pheromone protein | - |
| RK73_RS07340 (RK73_07340) | ligA | 1378340..1380343 (-) | 2004 | WP_000774565.1 | NAD-dependent DNA ligase LigA | - |
| RK73_RS07345 (RK73_07345) | pcrA | 1380347..1382539 (-) | 2193 | WP_000992921.1 | DNA helicase PcrA | - |
Sequence
Protein
Download Length: 209 a.a. Molecular weight: 23545.29 Da Isoelectric Point: 5.3889
>NTDB_id=273895 RK73_RS07205 WP_000153530.1 1356590..1357219(-) (vraR) [Staphylococcus aureus strain FDAARGOS_15]
MTIKVLFVDDHEMVRIGISSYLSTQSDIEVVGEGASGKEAIAKAHELKPDLILMDLLMDDMDGVEATTQIKKDLPQIKVL
MLTSFIEDKEVYRALDAGVDSYILKTTSAKDIADAVRKTSRGESVFEPEVLVKMRNRMKKRAELYEMLTEREMEILLLIA
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ
MTIKVLFVDDHEMVRIGISSYLSTQSDIEVVGEGASGKEAIAKAHELKPDLILMDLLMDDMDGVEATTQIKKDLPQIKVL
MLTSFIEDKEVYRALDAGVDSYILKTTSAKDIADAVRKTSRGESVFEPEVLVKMRNRMKKRAELYEMLTEREMEILLLIA
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ
Nucleotide
Download Length: 630 bp
>NTDB_id=273895 RK73_RS07205 WP_000153530.1 1356590..1357219(-) (vraR) [Staphylococcus aureus strain FDAARGOS_15]
ATGACGATTAAAGTATTGTTTGTGGATGATCATGAAATGGTACGTATAGGAATTTCAAGTTATCTATCAACGCAAAGTGA
TATTGAAGTAGTTGGTGAAGGCGCTTCTGGTAAAGAAGCAATTGCCAAAGCCCATGAGTTGAAGCCAGATTTAATTTTAA
TGGATTTACTTATGGATGACATGGATGGTGTAGAAGCGACGACTCAGATTAAAAAAGATTTACCGCAAATTAAAGTATTA
ATGTTAACTAGTTTTATTGAAGATAAAGAGGTATATCGTGCATTAGATGCAGGTGTCGATAGTTACATTTTAAAAACAAC
AAGTGCAAAAGATATCGCCGATGCAGTTCGTAAAACTTCTAGAGGAGAATCTGTTTTTGAACCGGAAGTTTTAGTGAAAA
TGCGTAACCGTATGAAAAAGCGCGCAGAGTTATATGAAATGCTTACAGAACGAGAAATGGAAATATTATTATTGATTGCG
AAAGGTTACTCAAATCAAGAAATTGCTAGTGCATCGCATATTACTATTAAAACGGTTAAGACACATGTGAGTAACATTTT
AAGTAAGTTAGAAGTGCAAGATAGAACACAAGCTGTTATCTATGCATTCCAACATAATTTAATTCAATAG
ATGACGATTAAAGTATTGTTTGTGGATGATCATGAAATGGTACGTATAGGAATTTCAAGTTATCTATCAACGCAAAGTGA
TATTGAAGTAGTTGGTGAAGGCGCTTCTGGTAAAGAAGCAATTGCCAAAGCCCATGAGTTGAAGCCAGATTTAATTTTAA
TGGATTTACTTATGGATGACATGGATGGTGTAGAAGCGACGACTCAGATTAAAAAAGATTTACCGCAAATTAAAGTATTA
ATGTTAACTAGTTTTATTGAAGATAAAGAGGTATATCGTGCATTAGATGCAGGTGTCGATAGTTACATTTTAAAAACAAC
AAGTGCAAAAGATATCGCCGATGCAGTTCGTAAAACTTCTAGAGGAGAATCTGTTTTTGAACCGGAAGTTTTAGTGAAAA
TGCGTAACCGTATGAAAAAGCGCGCAGAGTTATATGAAATGCTTACAGAACGAGAAATGGAAATATTATTATTGATTGCG
AAAGGTTACTCAAATCAAGAAATTGCTAGTGCATCGCATATTACTATTAAAACGGTTAAGACACATGTGAGTAACATTTT
AAGTAAGTTAGAAGTGCAAGATAGAACACAAGCTGTTATCTATGCATTCCAACATAATTTAATTCAATAG
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| vraR | Staphylococcus aureus N315 |
99.522 |
100 |
0.995 |
| degU | Bacillus subtilis subsp. subtilis str. 168 |
34.821 |
100 |
0.373 |