Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   CCU04_RS00175 Genome accession   NZ_CP031908
Coordinates   33132..33722 (+) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli O103:H2 strain FWSEC0007     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 28132..38722
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CCU04_RS00150 (CCU04_000150) emrD 28614..29798 (-) 1185 WP_000828746.1 multidrug efflux MFS transporter EmrD -
  CCU04_RS28185 ysdE 29880..29954 (+) 75 WP_211180519.1 protein YsdE -
  CCU04_RS00155 (CCU04_000160) tisB 30217..30306 (-) 90 WP_000060506.1 type I toxin-antitoxin system toxin TisB -
  CCU04_RS00160 (CCU04_000180) ivbL 30871..30969 (+) 99 WP_001315912.1 ilvB operon leader peptide IvbL -
  CCU04_RS00165 (CCU04_000185) ilvB 31075..32763 (+) 1689 WP_000168480.1 acetolactate synthase large subunit -
  CCU04_RS00170 (CCU04_000190) ilvN 32767..33057 (+) 291 WP_001181706.1 acetolactate synthase small subunit -
  CCU04_RS00175 (CCU04_000195) letA 33132..33722 (+) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  CCU04_RS00180 (CCU04_000200) uhpB 33722..35224 (+) 1503 WP_001295243.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  CCU04_RS00185 (CCU04_000205) uhpC 35234..36553 (+) 1320 WP_000936565.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  CCU04_RS00190 (CCU04_000210) uhpT 36691..38082 (+) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=273151 CCU04_RS00175 WP_000633668.1 33132..33722(+) (letA) [Escherichia coli O103:H2 strain FWSEC0007]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=273151 CCU04_RS00175 WP_000633668.1 33132..33722(+) (letA) [Escherichia coli O103:H2 strain FWSEC0007]
ATGATCACCGTTGCCCTTATAGACGATCACCTCATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCCGATATCTCCGGTCTGGAACTGCTAAGCCAGCTGCCGAAAGGTATGGCGACAATAATGCTCTCTGTT
CATGACAGTCCGGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCGCGCGGCTTTCTCTCCAAACGCTGTAGCCCTGACGA
ACTGATTGCGGCGGTGCATACGGTTGCTACGGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GTCAGGACCCGCTGACCAAACGTGAACGCCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCCGCC
GAACTGGGCTTGTCACCGAAAACGGTACACGTCCATCGCGCCAATCTGATGGAAAAACTGGGCGTCAGTAACGACGTAGA
ACTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378

Multiple sequence alignment