Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   C8200_RS02370 Genome accession   NZ_CP031902
Coordinates   484211..484843 (-) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli O104:H4 strain FWSEC0009     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 479211..489843
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C8200_RS02345 (C8200_02450) yhfG 479343..479510 (+) 168 WP_000736862.1 YhfG family protein -
  C8200_RS02350 (C8200_02455) fic 479500..480102 (+) 603 WP_001280641.1 putative adenosine monophosphate-protein transferase Fic -
  C8200_RS02355 (C8200_02460) pabA 480134..480697 (+) 564 WP_000601847.1 aminodeoxychorismate synthase component 2 -
  C8200_RS02360 (C8200_02465) argD 480783..482003 (+) 1221 WP_000963784.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  C8200_RS02365 (C8200_02470) yhfK 482070..484160 (-) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  C8200_RS02370 (C8200_02475) crp 484211..484843 (-) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  C8200_RS02375 (C8200_02485) yhfA 485145..485549 (+) 405 WP_001148908.1 OsmC family protein -
  C8200_RS02380 (C8200_02490) prkB 485604..486473 (-) 870 WP_001274680.1 phosphoribulokinase -
  C8200_RS02385 (C8200_02495) yheU 486527..486745 (-) 219 WP_000907085.1 YheU family protein -
  C8200_RS02390 (C8200_02500) yheT 486739..487761 (-) 1023 WP_000057405.1 hydrolase -
  C8200_RS02395 (C8200_02505) yheS 487761..489674 (-) 1914 WP_000634798.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=272996 C8200_RS02370 WP_000242755.1 484211..484843(-) (crp) [Escherichia coli O104:H4 strain FWSEC0009]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=272996 C8200_RS02370 WP_000242755.1 484211..484843(-) (crp) [Escherichia coli O104:H4 strain FWSEC0009]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCAGACGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATTGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTTGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467