Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilD   Type   Machinery gene
Locus tag   NMC_RS09695 Genome accession   NC_008767
Coordinates   1873113..1873973 (+) Length   286 a.a.
NCBI ID   WP_002241067.1    Uniprot ID   A1KVV2
Organism   Neisseria meningitidis FAM18     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1868113..1878973
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NMC_RS09675 (NMC1835) dapD 1868623..1869444 (-) 822 WP_002220281.1 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase -
  NMC_RS09680 - 1869454..1869684 (-) 231 WP_025462060.1 hypothetical protein -
  NMC_RS09685 (NMC1837) pgi 1869654..1871297 (-) 1644 WP_002247959.1 glucose-6-phosphate isomerase -
  NMC_RS09690 (NMC1838) pilG 1871807..1873039 (+) 1233 WP_002216405.1 type 4 pilus assembly protein PilG Machinery gene
  NMC_RS09695 (NMC1839) pilD 1873113..1873973 (+) 861 WP_002241067.1 prepilin peptidase Machinery gene
  NMC_RS09700 (NMC1841) coaE 1873975..1874607 (+) 633 WP_002216402.1 dephospho-CoA kinase -
  NMC_RS09705 (NMC1842) - 1874600..1874809 (+) 210 WP_002216401.1 DNA gyrase inhibitor YacG -
  NMC_RS09710 (NMC1844) pilF 1874894..1876570 (-) 1677 WP_002221967.1 type IV-A pilus assembly ATPase PilB Machinery gene
  NMC_RS09720 (NMC1845) - 1877062..1877508 (-) 447 WP_002220271.1 DUF441 domain-containing protein -
  NMC_RS09725 (NMC1846) ispB 1877513..1878487 (-) 975 WP_002247958.1 octaprenyl diphosphate synthase -

Sequence

Protein


Download         Length: 286 a.a.        Molecular weight: 31331.48 Da        Isoelectric Point: 9.1920

>NTDB_id=27252 NMC_RS09695 WP_002241067.1 1873113..1873973(+) (pilD) [Neisseria meningitidis FAM18]
MSDLSVLSPFAVPLAAVFGLLVGSFLNVVIYRVPVMMERGWTVFAKKHLNLPLTEKESRTFNLMKPDSCCPKCRVPIRAW
QNIPIVSYLLLRGKCASCQTKISIRYPLIELLTGVLFGLVAWQYGWSWITLGGLILTAFLISLTFIDADTQYLPDSMTLP
LIWLGLIFNLDGGFVPLQSAVLGAVAGYGSIWLLCAVYKLIKGEIGMGNGDFKLIAALGAWLGISALPVLIFVSSLIGLV
AAIVMRVAKGQHFAFGPALTVSGWIIFTANDSVWRAVNWWLTHPVL

Nucleotide


Download         Length: 861 bp        

>NTDB_id=27252 NMC_RS09695 WP_002241067.1 1873113..1873973(+) (pilD) [Neisseria meningitidis FAM18]
ATGTCTGATTTGTCTGTATTGTCGCCGTTTGCCGTGCCTTTGGCAGCGGTGTTCGGGCTGCTGGTCGGCAGTTTCTTAAA
CGTCGTCATTTACCGCGTGCCGGTCATGATGGAACGCGGCTGGACGGTATTTGCCAAAAAACATTTAAACCTGCCGCTGA
CCGAAAAGGAAAGCCGTACCTTCAACCTGATGAAACCGGATTCCTGCTGTCCCAAATGCCGCGTGCCGATACGCGCGTGG
CAGAACATCCCGATTGTCAGCTACCTGCTCCTGCGCGGCAAATGCGCTTCCTGCCAAACCAAAATCAGCATACGTTATCC
CTTAATCGAGCTGCTGACCGGCGTATTATTCGGGCTGGTCGCCTGGCAATACGGCTGGTCTTGGATTACATTGGGCGGTT
TGATACTGACCGCGTTTCTGATTTCCCTGACCTTTATCGATGCGGACACCCAATACCTGCCCGACTCGATGACACTGCCC
TTGATTTGGCTGGGGCTGATATTTAATTTGGACGGCGGCTTCGTGCCTTTGCAGTCTGCCGTTTTAGGTGCGGTTGCCGG
CTATGGTTCGATATGGCTTTTATGCGCGGTATATAAACTGATTAAAGGCGAAATCGGTATGGGCAACGGAGATTTCAAAC
TGATTGCCGCATTGGGCGCGTGGCTCGGCATATCCGCATTGCCCGTGCTGATTTTTGTTTCCTCGCTGATCGGTTTGGTC
GCGGCAATCGTTATGCGCGTCGCCAAGGGGCAGCATTTTGCCTTCGGCCCCGCACTGACAGTTTCGGGCTGGATAATTTT
TACGGCAAACGATTCCGTATGGCGGGCGGTCAACTGGTGGCTGACCCATCCGGTGCTGTAA

Domains

Predicted by InterproScan.

Type IV leader peptidase family (Peptidase_A24)

(134-242)

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(17-124)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A1KVV2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilD Neisseria gonorrhoeae MS11

96.14

99.65

0.958
  pilD Vibrio cholerae strain A1552

44.444

100

0.448
  pilD Acinetobacter baumannii D1279779

46.97

92.308

0.434
  pilD Acinetobacter nosocomialis M2

46.97

92.308

0.434
  pilD Vibrio campbellii strain DS40M4

44.565

96.503

0.43

Multiple sequence alignment