Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   ECE24377A_RS20700 Genome accession   NC_009801
Coordinates   3800827..3801459 (+) Length   210 a.a.
NCBI ID   WP_000242756.1    Uniprot ID   A7ZSN3
Organism   Escherichia coli O139:H28 str. E24377A     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3795827..3806459
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ECE24377A_RS20670 (EcE24377A_3822) yheS 3795996..3797909 (+) 1914 WP_000634798.1 ABC transporter ATP-binding protein -
  ECE24377A_RS20675 (EcE24377A_3823) yheT 3797909..3798931 (+) 1023 WP_000057405.1 hydrolase -
  ECE24377A_RS20680 (EcE24377A_3824) yheU 3798925..3799143 (+) 219 WP_000907085.1 YheU family protein -
  ECE24377A_RS20685 (EcE24377A_3825) prkB 3799197..3800066 (+) 870 WP_001274680.1 phosphoribulokinase -
  ECE24377A_RS20690 (EcE24377A_3826) yhfA 3800121..3800525 (-) 405 WP_001148908.1 OsmC family protein -
  ECE24377A_RS20700 (EcE24377A_3827) crp 3800827..3801459 (+) 633 WP_000242756.1 cAMP-activated global transcriptional regulator CRP Regulator
  ECE24377A_RS20705 (EcE24377A_3828) yhfK 3801510..3803600 (+) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  ECE24377A_RS20710 (EcE24377A_3829) argD 3803667..3804887 (-) 1221 WP_000963785.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  ECE24377A_RS20715 (EcE24377A_3830) pabA 3804973..3805536 (-) 564 WP_000601847.1 aminodeoxychorismate synthase component 2 -
  ECE24377A_RS20720 (EcE24377A_3831) fic 3805568..3806170 (-) 603 WP_001280624.1 putative adenosine monophosphate-protein transferase Fic -
  ECE24377A_RS20725 yhfG 3806160..3806327 (-) 168 WP_000736860.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23656.43 Da        Isoelectric Point: 8.2710

>NTDB_id=27252 ECE24377A_RS20700 WP_000242756.1 3800827..3801459(+) (crp) [Escherichia coli O139:H28 str. E24377A]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMSRRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=27252 ECE24377A_RS20700 WP_000242756.1 3800827..3801459(+) (crp) [Escherichia coli O139:H28 str. E24377A]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGTCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAACCTGGCAAAACAACCAGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A7ZSN3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.238

100

0.952
  crp Haemophilus influenzae Rd KW20

77.451

97.143

0.752
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment