Detailed information NTG0272369

Bioinformatically predicted

Overview

• Name: crp
• Type: Regulator
• Locus tag: D1100_RS10630
• Genome accession: NZ_CP031869
• Coordinates: 2236364..2237038 (-)
• Length: 224 a.a.
• NCBI ID: WP_005599747.1
• Uniprot ID: -
• Organism: Actinobacillus pleuropneumoniae strain WF83
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2231364..2242038

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
D1100_RS10600 (D1100_10650)	adhP	2231460..2232509 (+)	1050	WP_005602862.1	alcohol dehydrogenase AdhP	-
D1100_RS10605 (D1100_10655)	miaA	2232641..2233585 (+)	945	WP_005618608.1	tRNA (adenosine(37)-N6)-dimethylallyltransferase MiaA	-
D1100_RS10610 (D1100_10660)	hfq	2233650..2233928 (+)	279	WP_005599741.1	RNA chaperone Hfq	-
D1100_RS10615 (D1100_10665)	hflX	2233966..2235333 (+)	1368	WP_080515077.1	ribosome rescue GTPase HflX	-
D1100_RS10620 (D1100_10670)	-	2235369..2235929 (-)	561	WP_005613491.1	TIGR00730 family Rossman fold protein	-
D1100_RS10625 (D1100_10675)	-	2235992..2236315 (+)	324	WP_005602867.1	MazG nucleotide pyrophosphohydrolase domain-containing protein	-
D1100_RS10630 (D1100_10680)	crp	2236364..2237038 (-)	675	WP_005599747.1	cAMP-activated global transcriptional regulator CRP	Regulator
D1100_RS10635 (D1100_10685)	-	2237116..2237334 (-)	219	WP_005599748.1	YheU family protein	-
D1100_RS10640 (D1100_10690)	slmA	2237340..2237948 (-)	609	WP_237601117.1	nucleoid occlusion factor SlmA	-
D1100_RS10645 (D1100_10695)	dut	2238054..2238509 (-)	456	WP_005599752.1	dUTP diphosphatase	-
D1100_RS10650 (D1100_10700)	coaBC	2238518..2239723 (-)	1206	WP_005602882.1	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC	-
D1100_RS10655 (D1100_10705)	radC	2239931..2240593 (+)	663	WP_005599756.1	RadC family protein	Machinery gene
D1100_RS10660 (D1100_10710)	rpmB	2240762..2240998 (+)	237	WP_005599762.1	50S ribosomal protein L28	-
D1100_RS10665 (D1100_10715)	rpmG	2241010..2241180 (+)	171	WP_005599764.1	50S ribosomal protein L33	-

Sequence

Protein

• Length: 224 a.a.
• Molecular weight: 25147.02 Da
• Isoelectric Point: 6.5834

>NTDB_id=272369 D1100_RS10630 WP_005599747.1 2236364..2237038(-) (crp) [Actinobacillus pleuropneumoniae strain WF83]
MQDISISTPQLDSELSAPSIHDPAVEWFLTHCHIHRYPSKYTLIHAGEDAESLFYIVSGSVAVFIKDEEGKEMILSHLGQ
GEFVGEISLFEDTIQPRTAWVKTKGACEIAEISYKKFKQLVHLNPDILMYLSAQMARRLRQTSRQVSNLAFLDVTGRIAQ
TLMNLAKMPDAMTHPEGMQIKITRQEIGQMVGCSRETVGRILKMLEDEGLISAHGKTIVVYGTR

Nucleotide

• Length: 675 bp

>NTDB_id=272369 D1100_RS10630 WP_005599747.1 2236364..2237038(-) (crp) [Actinobacillus pleuropneumoniae strain WF83]
ATGCAAGATATTTCAATTTCAACACCTCAGCTAGACAGTGAGCTGTCCGCCCCGTCTATTCATGATCCGGCGGTGGAATG
GTTTCTGACTCACTGTCATATTCATCGTTATCCGTCAAAATATACGCTTATTCATGCGGGTGAGGATGCCGAATCATTAT
TCTATATCGTCAGCGGCTCCGTTGCAGTGTTTATTAAAGATGAAGAAGGGAAAGAAATGATCCTTTCTCACCTCGGTCAA
GGTGAATTTGTCGGTGAAATCAGTTTATTCGAAGACACTATTCAACCGCGTACCGCTTGGGTCAAAACCAAAGGCGCTTG
CGAAATTGCGGAAATCTCGTATAAAAAATTCAAACAGCTTGTGCATTTAAATCCGGATATTCTTATGTATCTTTCCGCGC
AAATGGCTCGCCGCCTACGCCAAACCTCACGCCAAGTAAGTAACCTCGCTTTCTTAGACGTAACCGGTCGTATCGCACAA
ACCTTAATGAATTTGGCGAAAATGCCGGATGCGATGACCCATCCGGAAGGAATGCAAATTAAGATTACCCGCCAAGAAAT
CGGTCAAATGGTCGGTTGTTCTCGAGAAACGGTCGGTAGAATCTTAAAAATGCTAGAAGATGAAGGCTTAATTTCAGCAC
ACGGTAAAACCATTGTCGTTTATGGCACTCGCTAA

Domains

Predicted by InterProScan.

• Crp-like helix-turn-helix domain (HTH_Crp_2) (156-220)

• Cyclic nucleotide-binding domain (cNMP_binding) (36-121)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
crp	Vibrio cholerae strain A1552	77.34	90.625	0.701
crp	Haemophilus influenzae Rd KW20	73.892	90.625	0.67
crp	Acinetobacter baumannii D1279779	45.794	95.536	0.437