Detailed information NTG0272203

Bioinformatically predicted

Overview

• Name: crp
• Type: Regulator
• Locus tag: D1103_RS10560
• Genome accession: NZ_CP031864
• Coordinates: 2231900..2232574 (-)
• Length: 224 a.a.
• NCBI ID: WP_005599747.1
• Uniprot ID: -
• Organism: Actinobacillus pleuropneumoniae serovar 10 str. D13039
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2226900..2237574

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
D1103_RS10530 (D1103_10605)	adhP	2226996..2228045 (+)	1050	WP_005602862.1	alcohol dehydrogenase AdhP	-
D1103_RS10535 (D1103_10610)	miaA	2228177..2229121 (+)	945	WP_043995181.1	tRNA (adenosine(37)-N6)-dimethylallyltransferase MiaA	-
D1103_RS10540 (D1103_10615)	hfq	2229186..2229464 (+)	279	WP_005599741.1	RNA chaperone Hfq	-
D1103_RS10545 (D1103_10620)	hflX	2229502..2230869 (+)	1368	WP_080515077.1	ribosome rescue GTPase HflX	-
D1103_RS10550 (D1103_10625)	-	2230905..2231465 (-)	561	WP_005613491.1	TIGR00730 family Rossman fold protein	-
D1103_RS10555 (D1103_10630)	-	2231528..2231851 (+)	324	WP_005602867.1	MazG nucleotide pyrophosphohydrolase domain-containing protein	-
D1103_RS10560 (D1103_10635)	crp	2231900..2232574 (-)	675	WP_005599747.1	cAMP-activated global transcriptional regulator CRP	Regulator
D1103_RS10565 (D1103_10640)	-	2232652..2232870 (-)	219	WP_005599748.1	YheU family protein	-
D1103_RS10570 (D1103_10645)	slmA	2232876..2233484 (-)	609	WP_005620316.1	nucleoid occlusion factor SlmA	-
D1103_RS10575 (D1103_10650)	dut	2233590..2234045 (-)	456	WP_005599752.1	dUTP diphosphatase	-
D1103_RS10580 (D1103_10655)	coaBC	2234054..2235259 (-)	1206	WP_005602882.1	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC	-
D1103_RS10585 (D1103_10660)	radC	2235467..2236138 (+)	672	WP_005613496.1	RadC family protein	Machinery gene
D1103_RS10590 (D1103_10665)	rpmB	2236298..2236534 (+)	237	WP_005599762.1	50S ribosomal protein L28	-
D1103_RS10595 (D1103_10670)	rpmG	2236546..2236716 (+)	171	WP_005613503.1	50S ribosomal protein L33	-

Sequence

Protein

• Length: 224 a.a.
• Molecular weight: 25147.02 Da
• Isoelectric Point: 6.5834

>NTDB_id=272203 D1103_RS10560 WP_005599747.1 2231900..2232574(-) (crp) [Actinobacillus pleuropneumoniae serovar 10 str. D13039]
MQDISISTPQLDSELSAPSIHDPAVEWFLTHCHIHRYPSKYTLIHAGEDAESLFYIVSGSVAVFIKDEEGKEMILSHLGQ
GEFVGEISLFEDTIQPRTAWVKTKGACEIAEISYKKFKQLVHLNPDILMYLSAQMARRLRQTSRQVSNLAFLDVTGRIAQ
TLMNLAKMPDAMTHPEGMQIKITRQEIGQMVGCSRETVGRILKMLEDEGLISAHGKTIVVYGTR

Nucleotide

• Length: 675 bp

>NTDB_id=272203 D1103_RS10560 WP_005599747.1 2231900..2232574(-) (crp) [Actinobacillus pleuropneumoniae serovar 10 str. D13039]
ATGCAAGATATTTCAATTTCAACACCTCAGCTAGACAGTGAGCTGTCCGCCCCGTCTATTCATGATCCGGCGGTGGAATG
GTTTCTGACTCACTGTCATATTCATCGTTATCCGTCAAAATATACGCTTATTCATGCGGGTGAGGATGCCGAATCATTAT
TCTATATCGTCAGCGGCTCCGTTGCAGTGTTTATTAAAGATGAAGAAGGGAAAGAAATGATCCTTTCTCACCTCGGTCAA
GGTGAATTTGTCGGTGAAATCAGTTTATTCGAAGACACTATTCAACCGCGTACCGCTTGGGTCAAAACCAAAGGCGCTTG
CGAAATTGCGGAAATCTCGTATAAAAAATTCAAACAGCTTGTGCATTTAAATCCGGATATTCTTATGTATCTTTCCGCAC
AAATGGCTCGCCGCCTACGCCAAACCTCACGCCAAGTAAGTAACCTCGCTTTCTTAGACGTAACCGGTCGTATCGCACAA
ACCTTAATGAATCTGGCAAAAATGCCGGATGCAATGACCCACCCTGAAGGAATGCAAATTAAGATTACCCGCCAAGAAAT
CGGTCAAATGGTCGGTTGTTCTCGAGAAACGGTCGGTAGAATCTTAAAAATGCTAGAAGATGAAGGCTTAATTTCAGCAC
ACGGTAAAACCATTGTCGTTTATGGCACTCGCTAA

Domains

Predicted by InterProScan.

• Crp-like helix-turn-helix domain (HTH_Crp_2) (156-220)

• Cyclic nucleotide-binding domain (cNMP_binding) (36-121)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
crp	Vibrio cholerae strain A1552	77.34	90.625	0.701
crp	Haemophilus influenzae Rd KW20	73.892	90.625	0.67
crp	Acinetobacter baumannii D1279779	45.794	95.536	0.437