Detailed information NTG0271983

Bioinformatically predicted

Overview

• Name: crp
• Type: Regulator
• Locus tag: D1107_RS10095
• Genome accession: NZ_CP031860
• Coordinates: 2147873..2148547 (-)
• Length: 224 a.a.
• NCBI ID: WP_005599747.1
• Uniprot ID: -
• Organism: Actinobacillus pleuropneumoniae strain 3906
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2142873..2153547

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
D1107_RS10065 (D1107_10160)	adhP	2142975..2144018 (+)	1044	WP_237592801.1	alcohol dehydrogenase AdhP	-
D1107_RS10070 (D1107_10165)	miaA	2144150..2145094 (+)	945	WP_005618608.1	tRNA (adenosine(37)-N6)-dimethylallyltransferase MiaA	-
D1107_RS10075 (D1107_10170)	hfq	2145159..2145437 (+)	279	WP_005599741.1	RNA chaperone Hfq	-
D1107_RS10080 (D1107_10175)	hflX	2145475..2146842 (+)	1368	WP_272929940.1	ribosome rescue GTPase HflX	-
D1107_RS10085 (D1107_10180)	-	2146878..2147438 (-)	561	WP_005602866.1	TIGR00730 family Rossman fold protein	-
D1107_RS10090 (D1107_10185)	-	2147501..2147824 (+)	324	Protein_1937	MazG nucleotide pyrophosphohydrolase domain-containing protein	-
D1107_RS10095 (D1107_10190)	crp	2147873..2148547 (-)	675	WP_005599747.1	cAMP-activated global transcriptional regulator CRP	Regulator
D1107_RS10100 (D1107_10195)	-	2148625..2148843 (-)	219	WP_005599748.1	YheU family protein	-
D1107_RS10105 (D1107_10200)	slmA	2148849..2149457 (-)	609	WP_005620316.1	nucleoid occlusion factor SlmA	-
D1107_RS10110 (D1107_10205)	dut	2149563..2150018 (-)	456	WP_005599752.1	dUTP diphosphatase	-
D1107_RS10115 (D1107_10210)	coaBC	2150027..2151232 (-)	1206	WP_005602882.1	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC	-
D1107_RS10120 (D1107_10215)	radC	2151440..2152102 (+)	663	WP_005599756.1	RadC family protein	Machinery gene
D1107_RS10125 (D1107_10220)	rpmB	2152271..2152507 (+)	237	WP_005599762.1	50S ribosomal protein L28	-
D1107_RS10130 (D1107_10225)	rpmG	2152519..2152689 (+)	171	WP_005599764.1	50S ribosomal protein L33	-

Sequence

Protein

• Length: 224 a.a.
• Molecular weight: 25147.02 Da
• Isoelectric Point: 6.5834

>NTDB_id=271983 D1107_RS10095 WP_005599747.1 2147873..2148547(-) (crp) [Actinobacillus pleuropneumoniae strain 3906]
MQDISISTPQLDSELSAPSIHDPAVEWFLTHCHIHRYPSKYTLIHAGEDAESLFYIVSGSVAVFIKDEEGKEMILSHLGQ
GEFVGEISLFEDTIQPRTAWVKTKGACEIAEISYKKFKQLVHLNPDILMYLSAQMARRLRQTSRQVSNLAFLDVTGRIAQ
TLMNLAKMPDAMTHPEGMQIKITRQEIGQMVGCSRETVGRILKMLEDEGLISAHGKTIVVYGTR

Nucleotide

• Length: 675 bp

>NTDB_id=271983 D1107_RS10095 WP_005599747.1 2147873..2148547(-) (crp) [Actinobacillus pleuropneumoniae strain 3906]
ATGCAAGATATTTCAATTTCAACACCTCAGCTAGACAGTGAGCTGTCCGCCCCGTCTATTCATGATCCGGCGGTGGAATG
GTTTCTGACTCACTGTCATATTCATCGTTATCCGTCAAAATATACGCTTATTCATGCGGGTGAGGATGCCGAATCATTAT
TCTATATCGTCAGCGGCTCCGTTGCAGTGTTTATTAAAGATGAAGAAGGGAAAGAAATGATCCTTTCTCACCTCGGTCAA
GGTGAATTTGTCGGTGAAATCAGTTTATTTGAAGACACTATTCAACCGCGTACCGCTTGGGTCAAAACCAAAGGCGCTTG
CGAAATTGCGGAAATCTCGTATAAAAAATTCAAACAGCTTGTGCATTTAAATCCGGATATTTTAATGTATCTTTCCGCAC
AAATGGCTCGCCGCCTACGCCAAACCTCACGCCAAGTAAGTAACCTCGCTTTCTTAGACGTAACCGGTCGTATCGCACAA
ACCTTAATGAATCTGGCAAAAATGCCGGATGCAATGACCCACCCTGAAGGAATGCAAATTAAGATTACCCGCCAAGAAAT
CGGTCAAATGGTCGGTTGTTCTCGAGAAACGGTCGGTAGAATCTTAAAAATGCTAGAAGATGAAGGCTTAATTTCAGCAC
ACGGTAAAACCATTGTCGTTTATGGCACTCGCTAA

Domains

Predicted by InterProScan.

• Crp-like helix-turn-helix domain (HTH_Crp_2) (156-220)

• Cyclic nucleotide-binding domain (cNMP_binding) (36-121)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
crp	Vibrio cholerae strain A1552	77.34	90.625	0.701
crp	Haemophilus influenzae Rd KW20	73.892	90.625	0.67
crp	Acinetobacter baumannii D1279779	45.794	95.536	0.437