Detailed information NTG0271956

Bioinformatically predicted

Overview

• Name: comA/comEC
• Type: Machinery gene
• Locus tag: AM442_RS17730
• Genome accession: NZ_CP026711
• Coordinates: 3650085..3652517 (-)
• Length: 810 a.a.
• NCBI ID: WP_000472709.1
• Uniprot ID: A0A427QY69
• Organism: Acinetobacter baumannii strain AR_0063
• Function: ssDNA transport through the inner membrane (predicted from homology) DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
Prophage	3645408..3657546	3650085..3652517	within	0

Gene organization within MGE regions

Location: 3645408..3657546

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AM442_RS17705 (AM442_17700)	purM	3645408..3646478 (+)	1071	WP_000071984.1	phosphoribosylformylglycinamidine cyclo-ligase	-
AM442_RS17710 (AM442_17705)	purN	3646475..3647104 (+)	630	WP_000975533.1	phosphoribosylglycinamide formyltransferase	-
AM442_RS17715 (AM442_17710)	-	3647168..3647977 (-)	810	WP_000114071.1	alpha/beta fold hydrolase	-
AM442_RS17720 (AM442_17715)	sppA	3647996..3649012 (-)	1017	WP_001286612.1	signal peptide peptidase SppA	-
AM442_RS17725 (AM442_17720)	-	3649149..3650132 (+)	984	WP_001984639.1	lysophospholipid acyltransferase family protein	-
AM442_RS17730 (AM442_17725)	comA/comEC	3650085..3652517 (-)	2433	WP_000472709.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
AM442_RS17735 (AM442_17730)	lolD	3652602..3653288 (-)	687	WP_000049406.1	lipoprotein-releasing ABC transporter ATP-binding protein LolD	-
AM442_RS17740 (AM442_17735)	-	3653281..3654516 (-)	1236	WP_031974828.1	lipoprotein-releasing ABC transporter permease subunit	-
AM442_RS20340	-	3654654..3654734 (+)	81	Protein_3448	PilZ domain-containing protein	-
AM442_RS17745 (AM442_17740)	-	3654764..3655672 (-)	909	WP_001140078.1	DMT family transporter	-
AM442_RS17750 (AM442_17745)	-	3655683..3656168 (-)	486	WP_001985538.1	YaiI/YqxD family protein	-
AM442_RS17755 (AM442_17750)	-	3656425..3657366 (+)	942	WP_000795874.1	hypothetical protein	-

Sequence

Protein

• Length: 810 a.a.
• Molecular weight: 92409.78 Da
• Isoelectric Point: 8.5821

>NTDB_id=271956 AM442_RS17730 WP_000472709.1 3650085..3652517(-) (comA/comEC) [Acinetobacter baumannii strain AR_0063]
MFKIILLGWIGGIALMGIDFPLIMQYEKVGEALLLLAFIFYLYKRPMFVDRPFLKAVFCLLCTTSLFMVGYHYAEKALIE
RLEQRETDTRNLDIIVYINRLSEEKDNKVQQTAQVLNLSKEPVNWLLYLKSNNQNLLKNNQNLELGHYYRISGKTRPAHS
YATPGAFDQEKWFIQRNIMSGFNVRYIEPLSLDEIYRLGYQQHLKEQQSFSNSFRLNIEKLRLTFRQILNSSSLQQKGLI
LALLTGDESLLSDETQLQFKQLGISHLLAISGPHVLIFAIMLSWACHQFISRYHPQIYLWKPKQVLMAVPCCLGVLIYTA
FVGFEIPALRTLLSVLIFIGFLLLKQPIKPFTLLVYSASLLLLMDPFSVLSAGFWLSYGACFILLRIYQTIAQLPEQHFL
SLSSKMIFMSKVLIESQGKIFIALSPLTLLFFQQISWVAPLTNIIAVPIVGGVIVPLNIMAACAWFVIKPFGNMLFHFND
MLLSILLSCLGLLEKLSLPLQGISLTPLSLLAISCAIIILFLPKGILPKTWGILCCLPLVIMNKTSQQIQLNILDVGQGQ
AIFLQHPEQNWLIDTGGSYDEKIFSIGQNVVVPFLRQQGVRQLDHVVLSHLDQDHSGAFPLIQQEIPVKQLISNEQLPND
LKQPFQYCYQGQQWHYPELDIQILWPKEKDLAFVASNQNQYSCVVYLQFKKVGGYQNFLIMGDAGWEAEYELLKDYPNLK
IDVLVLGHHGSKHSSAYDFLATLKPKLAIASAGFDNRYGHPSQQVIARLKALHIPLKSTVEQGTLSFVLENHKIVLHDRR
LDRLWLSRGF

Nucleotide

• Length: 2433 bp

>NTDB_id=271956 AM442_RS17730 WP_000472709.1 3650085..3652517(-) (comA/comEC) [Acinetobacter baumannii strain AR_0063]
ATGTTTAAGATTATTCTATTGGGGTGGATTGGCGGTATTGCATTGATGGGAATAGATTTCCCTTTAATCATGCAATATGA
AAAAGTGGGCGAGGCTCTACTGTTACTTGCCTTTATTTTTTATCTTTATAAACGACCAATGTTCGTTGATCGACCATTTT
TAAAGGCAGTGTTTTGCTTATTATGTACAACAAGTCTTTTTATGGTTGGTTACCACTATGCTGAAAAAGCACTGATTGAA
CGATTAGAACAAAGAGAAACGGATACCCGAAATCTCGACATTATTGTCTATATAAACCGTTTAAGTGAAGAAAAAGATAA
TAAGGTTCAACAAACTGCACAAGTTCTAAATCTTTCTAAAGAACCGGTGAATTGGTTGCTATATTTAAAAAGTAATAATC
AAAATTTATTAAAGAATAATCAGAATCTTGAATTAGGTCACTATTATCGAATATCTGGAAAAACAAGACCTGCGCATAGT
TATGCCACCCCAGGAGCTTTTGATCAGGAAAAGTGGTTTATTCAGCGAAATATTATGTCTGGTTTTAACGTGAGATATAT
TGAGCCTTTAAGTCTCGATGAAATCTATCGATTGGGCTATCAGCAACATTTAAAAGAACAACAGTCTTTTTCCAATAGTT
TTCGTTTAAATATAGAAAAACTTCGCTTAACTTTTAGGCAAATATTAAACAGCTCATCTCTACAGCAAAAGGGTTTAATT
TTAGCTTTGCTGACAGGTGATGAAAGCCTTTTATCAGATGAAACTCAACTACAGTTCAAACAATTGGGAATTAGTCATTT
ATTGGCGATCTCAGGCCCACATGTGCTCATTTTTGCCATTATGTTATCTTGGGCATGTCATCAATTTATCAGTCGTTATC
ATCCTCAAATTTACTTATGGAAACCGAAACAGGTTTTGATGGCTGTACCATGCTGCCTTGGTGTTTTAATTTATACTGCA
TTTGTAGGTTTCGAAATTCCTGCACTACGAACATTATTATCAGTCCTTATATTTATTGGATTTCTATTATTAAAACAACC
TATTAAACCTTTTACATTACTCGTATATAGTGCAAGTCTACTGTTGCTAATGGACCCGTTTAGTGTGCTTTCTGCAGGTT
TTTGGCTGTCTTATGGGGCATGTTTTATTTTATTAAGAATTTACCAAACTATAGCGCAGCTACCTGAGCAACATTTTTTG
AGTCTGAGTTCAAAAATGATTTTTATGAGTAAGGTGTTAATTGAATCTCAAGGCAAAATATTTATTGCATTGAGTCCTTT
AACCTTACTTTTCTTTCAACAAATTTCTTGGGTTGCTCCATTAACCAATATTATTGCCGTGCCTATTGTTGGGGGTGTTA
TTGTCCCTTTAAACATCATGGCTGCTTGCGCATGGTTTGTAATAAAACCATTTGGAAATATGCTTTTTCATTTCAATGAT
ATGTTGCTCAGCATATTGCTGAGTTGTTTGGGCTTATTAGAAAAACTCTCTTTACCATTACAAGGTATAAGCTTGACGCC
ACTGTCTTTATTAGCGATTAGTTGTGCCATTATTATTTTATTTTTACCTAAAGGAATTCTGCCCAAAACTTGGGGAATAT
TATGTTGTTTACCCTTAGTTATTATGAACAAAACGAGTCAGCAAATTCAGCTTAATATTTTAGATGTTGGGCAGGGGCAG
GCTATTTTTCTACAACATCCCGAACAAAACTGGTTAATTGACACAGGCGGTTCTTACGATGAAAAAATATTTAGTATTGG
ACAAAATGTTGTAGTGCCTTTTCTACGTCAGCAAGGCGTAAGACAACTAGATCATGTTGTGCTATCCCATCTTGATCAAG
ACCATAGTGGCGCGTTTCCTCTTATTCAACAAGAGATTCCTGTAAAGCAGCTTATTTCGAATGAACAATTACCAAATGAT
TTAAAGCAACCATTCCAATATTGCTATCAAGGGCAACAATGGCATTATCCTGAGTTAGATATTCAAATTTTATGGCCTAA
AGAAAAAGATCTGGCTTTTGTTGCTTCTAATCAGAATCAATATTCTTGTGTTGTATATCTTCAATTTAAAAAAGTTGGTG
GTTACCAAAATTTTCTTATTATGGGCGATGCTGGATGGGAAGCTGAATACGAGTTATTAAAAGATTATCCTAACTTGAAG
ATAGATGTGTTGGTGCTAGGGCATCATGGAAGTAAGCACAGTTCGGCTTATGATTTCTTGGCGACCTTAAAACCTAAACT
GGCCATTGCATCGGCAGGGTTTGATAACCGTTATGGCCATCCTAGCCAACAAGTTATAGCACGTTTAAAAGCTCTACATA
TTCCGCTAAAAAGCACTGTGGAACAAGGAACCTTAAGTTTTGTGTTGGAAAACCACAAAATAGTTTTACATGACCGACGT
TTGGATAGGCTCTGGTTGAGTAGAGGTTTTTAA

Domains

Predicted by InterproScan.

• Domain of unknown function (DUF4131) (DUF4131) (33-188)

• Competence protein (Competence) (243-521)

• Metallo-beta-lactamase superfamily (Lactamase_B) (555-645)

3D structure

• AlphaFold DB: A0A427QY69

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA/comEC	Acinetobacter baumannii D1279779	99.012	100	0.99
comA/comEC	Acinetobacter baumannii strain A118	97.654	100	0.977
comA/comEC	Acinetobacter baylyi ADP1	50.432	100	0.505