Detailed information NTG0271459

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: C4N11_RS10455
• Genome accession: NZ_CP026670
• Coordinates: 1959921..1960931 (-)
• Length: 336 a.a.
• NCBI ID: WP_000990607.1
• Uniprot ID: A0A0B7LZL8
• Organism: Streptococcus pneumoniae strain endophthalmitis isolate 335
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 1954921..1965931

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
C4N11_RS10430 (C4N11_10430)	-	1954987..1956201 (-)	1215	WP_000666469.1	pyridoxal phosphate-dependent aminotransferase	-
C4N11_RS10435 (C4N11_10435)	-	1956357..1956650 (-)	294	WP_000977368.1	hypothetical protein	-
C4N11_RS10440 (C4N11_10440)	-	1956812..1957264 (+)	453	WP_000079148.1	universal stress protein	-
C4N11_RS10445 (C4N11_10445)	-	1957299..1958687 (-)	1389	WP_000453143.1	Cof-type HAD-IIB family hydrolase	-
C4N11_RS10450 (C4N11_10450)	-	1958753..1959715 (+)	963	WP_001124777.1	asparaginase	-
C4N11_RS10455 (C4N11_10455)	ccpA	1959921..1960931 (-)	1011	WP_000990607.1	catabolite control protein A	Regulator
C4N11_RS10460 (C4N11_10460)	-	1961356..1961955 (-)	600	WP_000866719.1	response regulator transcription factor	-
C4N11_RS10465 (C4N11_10465)	-	1961957..1963054 (-)	1098	WP_000893500.1	sensor histidine kinase	-
C4N11_RS10470 (C4N11_10470)	-	1963054..1963791 (-)	738	WP_000832916.1	ABC transporter permease	-
C4N11_RS10475 (C4N11_10475)	-	1963793..1964677 (-)	885	WP_001055978.1	ABC transporter ATP-binding protein	-
C4N11_RS10480 (C4N11_10480)	-	1964664..1964858 (-)	195	WP_000820189.1	hypothetical protein	-
C4N11_RS12700	-	1964855..1965061 (-)	207	Protein_1964	hypothetical protein	-

Sequence

Protein

• Length: 336 a.a.
• Molecular weight: 37073.01 Da
• Isoelectric Point: 5.3212

>NTDB_id=271459 C4N11_RS10455 WP_000990607.1 1959921..1960931(-) (ccpA) [Streptococcus pneumoniae strain endophthalmitis isolate 335]
MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
SLAKGIDDIAEMYKYNIVLANSDEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGLVFESKYSYDDGYALAERLISSN
ATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSDDSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERSSTRKRK

Nucleotide

• Length: 1011 bp

>NTDB_id=271459 C4N11_RS10455 WP_000990607.1 1959921..1960931(-) (ccpA) [Streptococcus pneumoniae strain endophthalmitis isolate 335]
ATGAATGCAGATGATACAGTAACCATTTATGATGTCGCTCGTGAAGCAGGTGTTTCCATGGCGACGGTCAGCCGTGTGGT
CAATGGCAATAAAAATGTAAAAGAGAATACCCGTAAAAAAGTGCTAGAGGTAATTGATCGTTTGGATTATCGTCCAAATG
CAGTTGCGCGTGGTCTTGCAAGTAAAAAGACAACCACTGTCGGTGTCGTGATTCCAAATATTACCAATGGTTATTTTTCG
AGTTTGGCTAAGGGGATTGATGATATTGCAGAAATGTACAAGTACAATATTGTCCTAGCTAATAGCGATGAAGATAACGA
GAAAGAAGTTTCTGTTGTCAATACCCTCTTTTCAAAGCAGGTAGATGGCATTATCTATATGGGGTATCACTTGACAGATA
AAATTCGCTCAGAATTTTCGCGTTCACGTACTCCGATTGTTCTCGCAGGAACTGTCGATGTTGAGCACCAGTTGCCAAGT
GTCAATATTGACTATAAGCAAGCAACAATTGATGCAGTGAGTTACCTTGCTAAAGAAAATGAGCGTATTGCTTTCGTTAG
CGGTCCGCTAGTGGATGACATCAATGGTAAGGTTCGTTTAGTTGGCTACAAGGAAACCTTGAAAAAAGCAGGAATCACTT
ATAGTGAGGGTTTGGTATTTGAATCTAAATATAGCTATGATGATGGTTACGCCTTAGCAGAGCGTTTGATTTCATCAAAT
GCAACTGCAGCAGTTGTGACAGGTGATGAGTTGGCAGCAGGAGTCTTGAACGGTTTGGCTGATAAGGGTGTTTCTGTGCC
AGAAGATTTTGAAATTATTACTAGTGATGATTCACAAATCTCACGCTTTACCCGTCCAAACTTGACAACGATTGCCCAAC
CTCTTTATGACCTTGGTGCCATTAGTATGCGTATGTTGACCAAGATTATGCATAAGGAAGAGTTGGAAGAACGTGAAGTT
CTCTTACCTCATGGTTTGACAGAACGTAGCTCAACACGAAAACGTAAATAG

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

• Periplasmic binding protein-like domain (Peripla_BP_3) (181-332)

3D structure

• AlphaFold DB: A0A0B7LZL8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	99.702	100	0.997
ccpA	Streptococcus gordonii str. Challis substr. CH1	87.126	99.405	0.866
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	57.704	98.512	0.568