Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   D0R13_RS02010 Genome accession   NZ_CP031833
Coordinates   417080..417712 (-) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain 2452     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 412080..422712
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  D0R13_RS01985 yhfG 412212..412379 (+) 168 WP_000736862.1 YhfG family protein -
  D0R13_RS01990 fic 412369..412971 (+) 603 WP_001280641.1 putative adenosine monophosphate-protein transferase Fic -
  D0R13_RS01995 pabA 413003..413566 (+) 564 WP_000601847.1 aminodeoxychorismate synthase component 2 -
  D0R13_RS02000 argD 413652..414872 (+) 1221 WP_004018668.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  D0R13_RS02005 yhfK 414939..417029 (-) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  D0R13_RS02010 crp 417080..417712 (-) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  D0R13_RS02020 yhfA 418014..418418 (+) 405 WP_001148908.1 OsmC family protein -
  D0R13_RS02025 prkB 418473..419342 (-) 870 WP_001274680.1 phosphoribulokinase -
  D0R13_RS02030 yheU 419396..419614 (-) 219 WP_000907085.1 YheU family protein -
  D0R13_RS02035 yheT 419608..420630 (-) 1023 WP_000057356.1 hydrolase -
  D0R13_RS02040 yheS 420630..422543 (-) 1914 WP_000634798.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=271364 D0R13_RS02010 WP_000242755.1 417080..417712(-) (crp) [Escherichia coli strain 2452]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=271364 D0R13_RS02010 WP_000242755.1 417080..417712(-) (crp) [Escherichia coli strain 2452]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTTTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCAGACGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATTGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467