Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrB   Type   Machinery gene
Locus tag   CH556_RS06010 Genome accession   NZ_CP031692
Coordinates   1217464..1219503 (-) Length   679 a.a.
NCBI ID   WP_042611248.1    Uniprot ID   -
Organism   Haemophilus influenzae strain P595-8370     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1212464..1224503
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CH556_RS06000 (CH556_06000) - 1213011..1215281 (+) 2271 WP_116945354.1 NADP-dependent malic enzyme -
  CH556_RS06005 (CH556_06005) - 1215509..1217434 (+) 1926 WP_162877115.1 LTA synthase family protein -
  CH556_RS06010 (CH556_06010) uvrB 1217464..1219503 (-) 2040 WP_042611248.1 excinuclease ABC subunit UvrB Machinery gene
  CH556_RS06020 (CH556_06020) zevB 1220107..1221075 (-) 969 WP_110426067.1 zinc transporter permease subunit ZevB -
  CH556_RS06025 (CH556_06025) zevA 1221078..1221698 (-) 621 WP_005650213.1 zinc transporter binding subunit ZevA -
  CH556_RS06030 (CH556_06030) - 1222023..1222328 (+) 306 WP_005650215.1 type II toxin-antitoxin system RelE/ParE family toxin -
  CH556_RS06035 (CH556_06035) - 1222339..1222662 (+) 324 WP_005650217.1 HigA family addiction module antitoxin -
  CH556_RS06040 (CH556_06040) ettA 1222825..1224495 (+) 1671 WP_048954581.1 energy-dependent translational throttle protein EttA -

Sequence

Protein


Download         Length: 679 a.a.        Molecular weight: 77554.06 Da        Isoelectric Point: 5.0409

>NTDB_id=270448 CH556_RS06010 WP_042611248.1 1217464..1219503(-) (uvrB) [Haemophilus influenzae strain P595-8370]
MSEKINTKPFILHSDFRPSGDQPQAIEKLAENLTDGLAHQTLLGVTGSGKTFTIANVIAQLNRPAMLLAPNKTLAAQLYA
EMKAFFPENAVEYFVSYYDYYQPEAYVPSSDTFIEKDASINDQIEQMRLSATKSFLERRDTIVVASVSAIYGLGDPDSYL
QMMLHLQQGAIIDQRQILAKLAELQYTRNDQAFQRGTFRVRGEIIDIFPAESDDRAVRIELFDDEIERLSLFDPLTGSSF
GAVPRFTIYPKTHYVTPRERILDAIENIKKELVSRREYFIKEHKLLEEQRISQRTQFDIEMMNELGYCSGIENYSRYLSG
RNEGEPPPTLFDYMPSDAILIIDESHVTVPQIGGMYRGDRSRKETLVEYGFRLPSALDNRPLRFEEFERLAPQTIYVSAT
PGPYELEKSGSEIIDQVVRPTGLLDPLIEIRPVSIQVDDLLSEARQRADKNERVLVTTLTKKMAEDLTDYLDEHGIRVRY
LHSDIDTVERVEIIRDLRLGEFDVLVGINLLREGLDIPEVSLVAILDADKEGFLRSERSLIQTIGRAARNLNGKAILYAD
SITKSMEKAITETNRRREKQIKYNEEHGIVPQALNKKVGELLDIGQGANQKAKANKQRGKMAAEPTALYNAPKNAKEYQQ
QIKKLEQQMYKFAQDLEFEKAAAIRDQLHQLREQFVFDN

Nucleotide


Download         Length: 2040 bp        

>NTDB_id=270448 CH556_RS06010 WP_042611248.1 1217464..1219503(-) (uvrB) [Haemophilus influenzae strain P595-8370]
ATGTCTGAAAAAATCAACACAAAACCGTTCATTCTACATTCCGACTTTCGTCCCTCTGGCGATCAGCCACAAGCTATCGA
AAAATTGGCTGAAAATTTAACGGATGGTTTGGCTCACCAAACTTTGCTCGGGGTAACTGGCTCGGGGAAAACCTTTACTA
TCGCCAATGTAATCGCTCAATTAAATCGCCCCGCGATGTTACTTGCACCAAATAAAACCCTTGCAGCTCAGCTTTATGCA
GAAATGAAAGCTTTTTTTCCAGAAAATGCGGTGGAATATTTTGTGTCTTACTATGATTATTATCAGCCAGAAGCCTATGT
GCCGAGCAGTGATACATTTATTGAAAAAGATGCGTCTATTAATGATCAAATTGAACAAATGCGACTTTCTGCGACGAAAT
CTTTTCTAGAACGTCGAGATACCATCGTGGTGGCTTCTGTTTCTGCAATTTATGGTTTGGGCGATCCTGATAGCTATTTA
CAAATGATGTTGCATTTACAACAAGGTGCCATTATCGATCAACGCCAAATTTTAGCGAAGTTAGCGGAATTACAATATAC
CCGAAATGATCAAGCATTTCAGCGTGGAACTTTCCGTGTTCGCGGAGAAATTATTGATATTTTCCCTGCGGAATCTGATG
ATCGTGCGGTGCGTATTGAATTATTTGATGATGAAATCGAGCGTTTAAGTTTATTTGATCCGCTCACTGGTAGTAGTTTT
GGTGCTGTCCCACGTTTTACGATCTATCCTAAAACTCACTATGTTACGCCAAGAGAACGTATTTTAGATGCGATAGAAAA
CATCAAAAAAGAACTCGTATCACGCCGTGAATATTTCATTAAAGAACATAAACTTTTAGAAGAACAACGAATTAGCCAAC
GAACCCAATTTGATATTGAAATGATGAATGAATTGGGCTATTGCTCGGGCATTGAAAACTACTCTCGCTATTTATCGGGA
AGAAATGAGGGCGAACCACCACCAACATTATTTGATTATATGCCCTCTGATGCCATTTTAATTATTGATGAATCTCATGT
AACTGTGCCTCAAATTGGTGGAATGTATCGTGGCGACCGTTCACGTAAAGAAACCTTAGTCGAATATGGTTTCCGTTTGC
CATCCGCCTTGGATAATCGTCCGTTACGCTTTGAGGAATTTGAACGCTTAGCTCCGCAAACCATTTATGTTTCCGCAACA
CCAGGGCCTTATGAATTAGAAAAATCAGGTAGTGAAATCATCGATCAAGTGGTTCGCCCCACTGGTTTACTTGATCCGCT
TATTGAAATTCGTCCAGTGTCAATTCAAGTGGATGATTTACTTTCCGAAGCTCGCCAAAGAGCGGATAAAAATGAGCGAG
TTTTAGTCACAACACTCACTAAAAAAATGGCGGAAGATTTAACGGATTATTTAGATGAACATGGGATTCGTGTGCGTTAT
CTACATTCTGATATTGATACCGTGGAACGCGTCGAAATTATCCGTGATTTGCGTTTAGGCGAATTTGATGTATTGGTTGG
AATTAACTTATTGCGTGAAGGTTTAGATATTCCTGAAGTGTCTCTTGTGGCGATTTTAGATGCGGACAAAGAAGGATTTT
TACGTTCTGAACGCTCTTTGATCCAAACCATCGGTCGTGCTGCGCGAAACTTAAATGGTAAAGCAATTTTATATGCAGAT
AGCATCACAAAATCCATGGAAAAAGCCATCACCGAAACTAATCGTCGTCGTGAAAAACAAATAAAATACAATGAAGAACA
TGGCATTGTGCCACAAGCATTGAATAAGAAAGTCGGTGAATTATTAGATATTGGGCAAGGTGCAAACCAAAAAGCGAAAG
CCAATAAACAACGTGGAAAAATGGCGGCAGAACCAACCGCACTTTATAATGCACCGAAAAATGCCAAAGAATATCAACAA
CAAATCAAAAAATTGGAACAACAAATGTATAAATTTGCGCAAGATTTGGAATTTGAAAAAGCCGCGGCAATTCGCGATCA
ATTACATCAATTACGTGAACAATTTGTTTTTGATAACTAA

Domains

Predicted by InterProScan.

Helicase conserved C-terminal domain (Helicase_C)

(446-549)

UvrB interaction domain (UvrB_inter)

(164-254)

Ultra-violet resistance protein B (UvrB)

(557-598)

Type III restriction enzyme, res subunit (ResIII)

(20-102)

UvrB/uvrC motif (UVR)

(640-674)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrB Streptococcus pneumoniae TIGR4

57.44

98.969

0.568
  uvrB Streptococcus pneumoniae R6

57.44

98.969

0.568
  uvrB Streptococcus pneumoniae D39

57.44

98.969

0.568