Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrB   Type   Machinery gene
Locus tag   CH576_RS06145 Genome accession   NZ_CP031691
Coordinates   1228758..1230797 (-) Length   679 a.a.
NCBI ID   WP_005694308.1    Uniprot ID   -
Organism   Haemophilus influenzae strain P615-8618     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1223758..1235797
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CH576_RS06135 (CH576_06135) - 1224308..1226578 (+) 2271 WP_116942027.1 NADP-dependent malic enzyme -
  CH576_RS06140 (CH576_06140) - 1226806..1228727 (+) 1922 Protein_1152 LTA synthase family protein -
  CH576_RS06145 (CH576_06145) uvrB 1228758..1230797 (-) 2040 WP_005694308.1 excinuclease ABC subunit UvrB Machinery gene
  CH576_RS06155 (CH576_06155) zevB 1231412..1232380 (-) 969 WP_005650211.1 zinc transporter permease subunit ZevB -
  CH576_RS06160 (CH576_06160) zevA 1232383..1233003 (-) 621 WP_105894794.1 zinc transporter binding subunit ZevA -
  CH576_RS06165 (CH576_06165) - 1233329..1233634 (+) 306 WP_012054677.1 type II toxin-antitoxin system RelE/ParE family toxin -
  CH576_RS06170 (CH576_06170) - 1233645..1233968 (+) 324 WP_050848570.1 HigA family addiction module antitoxin -

Sequence

Protein


Download         Length: 679 a.a.        Molecular weight: 77526.00 Da        Isoelectric Point: 5.0409

>NTDB_id=270384 CH576_RS06145 WP_005694308.1 1228758..1230797(-) (uvrB) [Haemophilus influenzae strain P615-8618]
MSEKINTKPFILHSDFRPSGDQPQAIEKLAENLTDGLAHQTLLGVTGSGKTFTIANVIAQLNRPAMLLAPNKTLAAQLYA
EMKAFFPENAVEYFVSYYDYYQPEAYVPSSDTFIEKDASINDQIEQMRLSATKSFLERRDTIVVASVSAIYGLGDPDSYL
QMMLHLQQGAIIDQRQILAKLAELQYTRNDQAFQRGTFRVRGEIIDIFPAESDDRAVRIELFDDEIERLSLFDPLTGSSF
GAVPRFTIYPKTHYVTPRERILDAIENIKKELVSRREYFIKEHKLLEEQRISQRTQFDIEMMNELGYCSGIENYSRYLSG
RNEGEPPPTLFDYMPPDAILIIDESHVTVPQIGGMYRGDRSRKETLVEYGFRLPSALDNRPLRFEEFERLAPQTIYVSAT
PGAYELEKSGSEIIDQVVRPTGLLDPLIEIRPVSIQVDDLLSEARQRADKNERVLVTTLTKKMAEDLTDYLDEHGIRVRY
LHSDIDTVERVEIIRDLRLGEFDVLVGINLLREGLDIPEVSLVAILDADKEGFLRSERSLIQTIGRAARNLNGKAILYAD
SITKSMEKAITETNRRREKQTKYNEEHGIVPQALNKKVGELLDIGQGANQKAKANKQRGKMAAEPTALYNAPKNAKEYQQ
QIKKLEQQMYKFAQDLEFEKAAAIRDQLHQLREQFVFDN

Nucleotide


Download         Length: 2040 bp        

>NTDB_id=270384 CH576_RS06145 WP_005694308.1 1228758..1230797(-) (uvrB) [Haemophilus influenzae strain P615-8618]
ATGTCTGAAAAAATCAACACAAAACCATTCATTCTGCATTCCGACTTTCGTCCCTCTGGCGATCAGCCACAAGCTATCGA
AAAATTGGCTGAAAATTTAACGGATGGTTTGGCGCATCAAACTTTGCTCGGGGTAACAGGCTCGGGGAAGACGTTTACTA
TCGCCAATGTAATCGCTCAATTAAATCGACCCGCAATGTTACTTGCGCCAAATAAAACCCTTGCTGCTCAGCTTTATGCA
GAAATGAAAGCTTTTTTTCCAGAAAATGCGGTGGAATATTTTGTGTCTTACTATGATTATTATCAGCCTGAAGCCTATGT
GCCCAGCAGTGATACATTTATTGAAAAAGATGCGTCTATTAATGATCAAATCGAACAAATGCGTCTTTCTGCGACGAAAT
CTTTTCTAGAACGTCGAGATACCATCGTGGTGGCTTCCGTTTCTGCAATTTATGGTTTGGGCGATCCTGATAGCTATTTA
CAAATGATGTTGCATTTACAACAAGGTGCCATTATCGATCAACGCCAAATTTTAGCGAAATTAGCGGAATTACAATATAC
CCGAAATGATCAAGCATTTCAGCGTGGAACTTTCCGTGTTCGCGGAGAAATTATTGATATTTTCCCTGCGGAATCTGATG
ATCGTGCGGTGCGTATTGAATTATTTGATGATGAAATCGAGCGTTTAAGTTTATTTGATCCGCTCACTGGTAGTAGTTTT
GGTGCTGTACCACGTTTTACGATCTATCCTAAAACTCACTATGTGACGCCAAGAGAACGTATTTTAGATGCGATAGAAAA
CATCAAAAAAGAACTGGTATCACGCCGTGAATACTTCATTAAAGAACATAAACTTTTAGAAGAACAGCGTATCAGCCAAC
GAACCCAATTTGATATTGAAATGATGAATGAATTGGGCTATTGCTCGGGAATTGAAAACTACTCTCGCTATTTATCGGGA
AGAAATGAGGGCGAACCACCACCAACATTATTTGATTATATGCCCCCTGATGCCATTTTAATTATTGATGAATCTCATGT
AACTGTGCCTCAAATTGGCGGGATGTATCGTGGCGACCGTTCACGTAAAGAAACCTTAGTCGAATATGGTTTCCGTTTGC
CGTCCGCATTGGATAATCGTCCGTTACGCTTTGAGGAATTTGAACGCTTAGCTCCGCAAACCATCTATGTTTCCGCAACA
CCAGGGGCCTATGAATTAGAGAAATCAGGTAGTGAAATCATCGATCAAGTGGTTCGCCCGACAGGTTTGCTTGATCCGCT
TATTGAAATTCGTCCAGTGTCAATTCAAGTGGATGATTTACTTTCCGAAGCTCGCCAAAGAGCGGATAAAAATGAGCGAG
TTTTAGTCACTACACTCACTAAAAAAATGGCGGAAGATTTAACGGATTATTTAGATGAACACGGGATTCGTGTGCGTTAT
CTACATTCTGATATTGATACCGTGGAACGCGTCGAAATTATCCGTGATTTGCGTTTAGGCGAATTTGATGTATTAGTGGG
AATTAACTTATTGCGTGAAGGTTTAGATATTCCAGAAGTGTCTCTTGTGGCGATTTTAGATGCTGACAAAGAAGGATTTT
TACGCTCCGAACGTTCTTTAATTCAAACCATCGGCCGTGCTGCACGAAACTTAAATGGTAAAGCGATTTTATATGCGGAT
AGCATCACAAAATCCATGGAAAAAGCCATCACCGAAACCAATCGTCGTCGTGAAAAACAAACAAAATACAATGAAGAACA
TGGCATTGTGCCACAGGCATTAAATAAGAAAGTCGGTGAATTATTAGATATTGGGCAAGGTGCAAACCAAAAAGCGAAAG
CCAATAAACAACGTGGAAAAATGGCGGCAGAACCAACCGCACTTTATAATGCACCGAAAAATGCCAAAGAATATCAACAA
CAAATCAAAAAATTGGAACAACAAATGTATAAATTTGCGCAAGATTTGGAATTTGAAAAAGCTGCGGCTATTCGCGATCA
ATTACATCAATTACGTGAACAGTTTGTTTTTGATAACTAA

Domains

Predicted by InterProScan.

Type III restriction enzyme, res subunit (ResIII)

(20-102)

Helicase conserved C-terminal domain (Helicase_C)

(446-549)

UvrB interaction domain (UvrB_inter)

(164-254)

Ultra-violet resistance protein B (UvrB)

(557-598)

UvrB/uvrC motif (UVR)

(640-674)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrB Streptococcus pneumoniae TIGR4

57.44

98.969

0.568
  uvrB Streptococcus pneumoniae R6

57.44

98.969

0.568
  uvrB Streptococcus pneumoniae D39

57.44

98.969

0.568