Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   DL545_RS10690 Genome accession   NZ_CP031653
Coordinates   2063004..2064836 (+) Length   610 a.a.
NCBI ID   WP_116995157.1    Uniprot ID   -
Organism   Escherichia coli strain UK_Dog_Liverpool     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 2058004..2069836
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DL545_RS10660 (DL545_10660) dcyD 2058231..2059217 (+) 987 WP_046659907.1 D-cysteine desulfhydrase -
  DL545_RS10665 (DL545_10665) tcyL 2059232..2059900 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  DL545_RS10670 (DL545_10670) tcyN 2059897..2060649 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  DL545_RS10675 (DL545_10675) sdiA 2060879..2061601 (+) 723 WP_001154276.1 transcriptional regulator SdiA -
  DL545_RS10680 (DL545_10680) yecF 2061668..2061892 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  DL545_RS26880 yecU 2061879..2062055 (-) 177 WP_000590347.1 protein YecU -
  DL545_RS27785 - 2062138..2062209 (-) 72 Protein_1956 transcriptional regulator -
  DL545_RS10685 (DL545_10685) letA 2062351..2063007 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  DL545_RS10690 (DL545_10690) uvrC 2063004..2064836 (+) 1833 WP_116995157.1 excinuclease ABC subunit UvrC Machinery gene
  DL545_RS10695 (DL545_10695) pgsA 2064893..2065441 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  DL545_RS10715 (DL545_10715) yecA 2066091..2066756 (+) 666 WP_000847902.1 UPF0149 family protein YecA -
  DL545_RS10720 (DL545_10720) tyrP 2066818..2068029 (-) 1212 WP_000797573.1 tyrosine transporter TyrP -
  DL545_RS10725 (DL545_10725) yecH 2068220..2068459 (+) 240 WP_000377225.1 YecH family metal-binding protein -
  DL545_RS10730 (DL545_10730) ftnA 2068497..2068994 (-) 498 WP_000917208.1 non-heme ferritin -
  DL545_RS10735 (DL545_10735) yecR 2069165..2069488 (-) 324 WP_046659905.1 YecR-like lipofamily protein -

Sequence

Protein


Download         Length: 610 a.a.        Molecular weight: 68188.97 Da        Isoelectric Point: 9.1789

>NTDB_id=268738 DL545_RS10690 WP_116995157.1 2063004..2064836(+) (uvrC) [Escherichia coli strain UK_Dog_Liverpool]
MSDQFDAKAFLKTVTSQPGVYRMYDAGGTVIYVGKAKDLKKRLSSYFRSNLASRKTEALVAQIQQIDVTVTHTETEALLL
EHNYIKLYQPRYNVLLRDDKSYPFIFLSGDTHPRLAMHRGAKHAKGEYFGPFPNGYAVRETLALLQKIFPIRQCENSVYR
NRSRPCLQYQIGRCLGPCVEGLVSEEEYAQQVEYVRLFLSGKDDQVLTQLISRMETASQNLEFEEAARIRDQIQAVRRVT
EKQFVSNTGDDLDVIGVAFDAGMACVHVLFIRQGKVLGSRSYFPKVPGGTELSEVVETFVGQFYLQGSQMRTLPGEILLD
FNLSDKTLLADSLSELAGREINVQTKPRGDRARYLKLARTNAATALTSKLSQQSTVHQRLTALASVLKLPEVKRMECFDI
SHTMGEQTVASCVVFDANGPLRAEYRRYNITGITPGDDYAAMNQVLRRRYGKAIDDSKIPDVILIDGGKGQLAQAKNVFA
ELDVSWDKNHPLLLGVAKGADRKAGLETLFFEPEGEGFSLPPDSPALHVIQHIRDESHDHAIGGHRKKRAKVKNTSSLET
IEGVGPKRRQMLLKYMGGLQGLRNASVEEIAKVPGISQGLAEKIFWSLKH

Nucleotide


Download         Length: 1833 bp        

>NTDB_id=268738 DL545_RS10690 WP_116995157.1 2063004..2064836(+) (uvrC) [Escherichia coli strain UK_Dog_Liverpool]
GTGAGTGATCAGTTTGACGCAAAAGCGTTTTTAAAAACCGTAACCAGCCAGCCAGGCGTTTATCGCATGTACGATGCTGG
TGGTACGGTTATCTATGTCGGCAAAGCGAAAGACCTGAAAAAACGGCTTTCCAGCTATTTCCGTAGCAACCTCGCTTCGC
GCAAAACCGAAGCGCTGGTCGCCCAGATTCAGCAAATTGATGTAACGGTTACTCATACAGAAACCGAAGCGCTGTTGCTG
GAACACAACTACATCAAACTCTATCAGCCGCGTTACAACGTTTTGCTACGCGATGATAAATCTTATCCTTTTATCTTCCT
GAGTGGCGATACCCACCCGCGTCTGGCGATGCATCGTGGTGCGAAGCATGCCAAAGGTGAATATTTCGGCCCGTTCCCGA
ATGGCTATGCCGTACGTGAAACTCTGGCACTACTGCAAAAGATTTTCCCCATTCGCCAGTGCGAAAATAGTGTTTATCGC
AATCGCTCGCGTCCGTGTCTGCAATATCAGATAGGGCGCTGTCTGGGACCGTGCGTTGAAGGACTGGTGAGTGAAGAAGA
ATACGCTCAGCAGGTCGAGTATGTGCGCCTGTTTTTGTCTGGCAAAGATGATCAGGTGCTTACGCAACTCATTAGCCGTA
TGGAAACTGCCAGTCAGAATCTGGAGTTTGAAGAAGCGGCACGTATTCGCGACCAAATTCAGGCGGTGCGACGCGTCACC
GAAAAACAGTTTGTTTCCAATACCGGCGACGACCTTGACGTTATTGGTGTGGCGTTCGATGCGGGCATGGCTTGTGTCCA
CGTATTGTTCATTCGTCAGGGCAAAGTGCTCGGCAGCCGCAGCTATTTCCCGAAAGTGCCTGGCGGTACGGAACTGAGCG
AGGTGGTAGAAACCTTCGTAGGTCAGTTCTATTTACAAGGCAGCCAGATGCGCACCTTACCGGGTGAGATCCTGCTCGAT
TTTAATCTTAGCGATAAAACGCTGCTCGCCGATTCCCTTTCAGAACTGGCGGGACGCGAGATTAATGTTCAAACCAAACC
TCGCGGCGATAGGGCGCGTTATCTGAAACTCGCGCGCACCAATGCGGCGACGGCCTTAACCAGCAAACTTTCGCAGCAAT
CTACCGTTCACCAGCGACTGACCGCGCTTGCCAGCGTGTTGAAATTGCCGGAAGTGAAGCGGATGGAGTGCTTTGACATC
AGCCATACCATGGGCGAACAAACCGTCGCTTCCTGTGTGGTGTTTGATGCTAACGGCCCGCTGCGTGCGGAGTATCGGCG
CTATAACATTACAGGCATCACGCCGGGCGATGATTATGCGGCGATGAATCAGGTGCTGCGTCGGCGTTATGGTAAAGCCA
TTGACGACAGTAAGATCCCGGATGTGATCCTTATCGACGGCGGCAAAGGCCAGCTTGCGCAGGCGAAAAATGTCTTCGCC
GAACTGGATGTCTCATGGGATAAAAATCATCCGCTGCTACTTGGCGTTGCCAAAGGAGCAGATCGTAAGGCTGGACTGGA
AACGCTGTTCTTTGAGCCGGAAGGTGAGGGATTTAGTTTGCCGCCAGATTCACCCGCGCTGCATGTTATCCAGCATATTC
GCGATGAATCACATGATCACGCGATTGGCGGGCACCGTAAAAAACGGGCGAAAGTCAAAAATACCAGTTCCCTGGAAACC
ATTGAAGGCGTCGGGCCAAAACGTCGGCAAATGTTGTTGAAATATATGGGCGGTTTGCAAGGTTTACGTAACGCCAGCGT
CGAGGAAATTGCAAAAGTGCCGGGTATTTCGCAAGGTCTGGCAGAAAAGATCTTCTGGTCGTTGAAACATTGA

Domains

Predicted by InterProScan.

UvrB/uvrC motif (UVR)

(205-237)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-542)

GIY-YIG catalytic domain (GIY-YIG)

(18-93)

Helix-hairpin-helix domain (HHH_5)

(558-609)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

37.562

99.508

0.374
  uvrC Streptococcus pneumoniae R6

37.232

99.508

0.37
  uvrC Streptococcus pneumoniae D39

37.232

99.508

0.37

Multiple sequence alignment