Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   DL545_RS10685 Genome accession   NZ_CP031653
Coordinates   2062351..2063007 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain UK_Dog_Liverpool     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2057351..2068007
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DL545_RS10660 (DL545_10660) dcyD 2058231..2059217 (+) 987 WP_046659907.1 D-cysteine desulfhydrase -
  DL545_RS10665 (DL545_10665) tcyL 2059232..2059900 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  DL545_RS10670 (DL545_10670) tcyN 2059897..2060649 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  DL545_RS10675 (DL545_10675) sdiA 2060879..2061601 (+) 723 WP_001154276.1 transcriptional regulator SdiA -
  DL545_RS10680 (DL545_10680) yecF 2061668..2061892 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  DL545_RS26880 yecU 2061879..2062055 (-) 177 WP_000590347.1 protein YecU -
  DL545_RS27785 - 2062138..2062209 (-) 72 Protein_1956 transcriptional regulator -
  DL545_RS10685 (DL545_10685) letA 2062351..2063007 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  DL545_RS10690 (DL545_10690) uvrC 2063004..2064836 (+) 1833 WP_116995157.1 excinuclease ABC subunit UvrC Machinery gene
  DL545_RS10695 (DL545_10695) pgsA 2064893..2065441 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  DL545_RS10715 (DL545_10715) yecA 2066091..2066756 (+) 666 WP_000847902.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=268737 DL545_RS10685 WP_000611335.1 2062351..2063007(+) (letA) [Escherichia coli strain UK_Dog_Liverpool]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=268737 DL545_RS10685 WP_000611335.1 2062351..2063007(+) (letA) [Escherichia coli strain UK_Dog_Liverpool]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486