NTDB

Overview

Name	ruvA	Type	Machinery gene
Locus tag	DZS39_RS08775	Genome accession	NZ_CP031628
Coordinates	1757458..1758054 (-)	Length	198 a.a.
NCBI ID	WP_011285268.1	Uniprot ID	Q48QW4
Organism	Streptococcus pyogenes strain MGAS28330
Function	homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 1752458..1763054

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DZS39_RS08740 (DZS39_08730)	-	1752518..1752823 (-)	306	WP_002982199.1	DUF1292 domain-containing protein	-
DZS39_RS08745 (DZS39_08735)	ruvX	1752835..1753254 (-)	420	WP_002982196.1	Holliday junction resolvase RuvX	-
DZS39_RS08750 (DZS39_08740)	-	1753251..1753520 (-)	270	WP_002982194.1	IreB family regulatory phosphoprotein	-
DZS39_RS08755 (DZS39_08745)	spx	1753634..1754032 (-)	399	WP_002982188.1	transcriptional regulator Spx	-
DZS39_RS08760 (DZS39_08750)	recA	1754323..1755459 (-)	1137	WP_011285265.1	recombinase RecA	-
DZS39_RS08765 (DZS39_08755)	cinA	1755548..1756819 (-)	1272	WP_011285266.1	competence/damage-inducible protein A	Machinery gene
DZS39_RS08770 (DZS39_08760)	-	1756888..1757448 (-)	561	WP_011018314.1	DNA-3-methyladenine glycosylase I	-
DZS39_RS08775 (DZS39_08765)	ruvA	1757458..1758054 (-)	597	WP_011285268.1	Holliday junction branch migration protein RuvA	Machinery gene
DZS39_RS08780 (DZS39_08770)	-	1758056..1759276 (-)	1221	WP_011285269.1	MFS transporter	-
DZS39_RS08785 (DZS39_08775)	hexB	1759287..1761269 (-)	1983	WP_021340699.1	DNA mismatch repair endonuclease MutL	Machinery gene
DZS39_RS08790 (DZS39_08780)	-	1761364..1762515 (-)	1152	WP_003058754.1	site-specific integrase	-
DZS39_RS09585 (DZS39_08785)	-	1762764..1762907 (+)	144	WP_011185066.1	putative holin-like toxin	-

Sequence

Protein

Download Length: 198 a.a. Molecular weight: 21811.12 Da Isoelectric Point: 6.2537

                                >NTDB_id=267590 DZS39_RS08775 WP_011285268.1 1757458..1758054(-) (ruvA) [Streptococcus pyogenes strain MGAS28330]

MYDYIKGQLTKITAKYIVVETNGLGYIINVANPYSFTDSVNQLVTIYLHQVIREDAHLLFGFHTEDEKDVFLKLISVSGI

GPTTALAIVAVDDNEGLVNAIDNSDIKYLMKFPKIGKKTAQQMVLDLAGKFVEAPQETGNTKARSNKAGNTQLDEAIEAL

LALGYKAAELKKIRAFFEGTSETAEQYIKSALKLLMKG

Nucleotide

Download Length: 597 bp

                                >NTDB_id=267590 DZS39_RS08775 WP_011285268.1 1757458..1758054(-) (ruvA) [Streptococcus pyogenes strain MGAS28330]

ATGTACGATTATATTAAAGGTCAATTGACCAAAATTACGGCAAAATACATTGTCGTTGAAACAAATGGACTAGGCTATAT

TATCAATGTAGCCAATCCTTATAGCTTTACAGATAGTGTCAACCAACTGGTAACTATTTACCTGCATCAAGTGATTCGTG

AGGATGCTCACTTGTTGTTTGGGTTTCATACGGAAGACGAAAAAGATGTTTTTCTGAAATTAATTTCTGTATCTGGCATT

GGCCCCACAACAGCTCTTGCTATTGTGGCAGTTGATGATAATGAGGGACTTGTGAATGCCATTGATAACAGTGACATTAA

GTACCTAATGAAATTTCCTAAAATTGGTAAAAAAACAGCGCAGCAAATGGTTCTTGACTTAGCTGGCAAATTTGTGGAGG

CTCCACAAGAGACTGGTAATACCAAAGCGCGCAGCAATAAAGCAGGCAATACTCAACTGGACGAAGCGATTGAAGCCCTC

CTTGCCCTCGGTTATAAGGCAGCGGAATTGAAGAAAATTCGTGCCTTCTTTGAAGGAACCTCTGAAACGGCCGAACAATA

CATCAAATCAGCCCTTAAACTATTAATGAAAGGCTAG

Domains

Predicted by InterProScan.

Helix-hairpin-helix domain (HHH_5)

(71-127)

RuvA N terminal domain (RuvA_N)

(1-61)

RuvA, C-terminal domain (RuvA_C)

(152-196)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure
AlphaFold DB	Q48QW4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
ruvA	Streptococcus pneumoniae TIGR4	67.005	99.495	0.667
ruvA	Streptococcus pneumoniae R6	67.005	99.495	0.667
ruvA	Streptococcus pneumoniae D39	67.005	99.495	0.667
ruvA	Bacillus subtilis subsp. subtilis str. 168	41.379	100	0.424

Detailed information NTG0267590