Detailed information NTG0267016

Bioinformatically predicted

Overview

• Name: comA/comEC
• Type: Machinery gene
• Locus tag: C2U64_RS06245
• Genome accession: NZ_CP026089
• Coordinates: 1041653..1044085 (+)
• Length: 810 a.a.
• NCBI ID: WP_002118905.1
• Uniprot ID: A0A009N350
• Organism: Acinetobacter pittii strain WCHAP005069
• Function: ssDNA transport through the inner membrane (predicted from homology) DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
Prophage	1040883..1048769	1041653..1044085	within	0

Gene organization within MGE regions

Location: 1040883..1048769

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
C2U64_RS06240 (C2U64_06225)	lolD	1040883..1041569 (+)	687	WP_002118798.1	lipoprotein-releasing ABC transporter ATP-binding protein LolD	-
C2U64_RS06245 (C2U64_06230)	comA/comEC	1041653..1044085 (+)	2433	WP_002118905.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
C2U64_RS06250 (C2U64_06235)	-	1044038..1045021 (-)	984	WP_002118440.1	lysophospholipid acyltransferase family protein	-
C2U64_RS06255 (C2U64_06240)	sppA	1045155..1046171 (+)	1017	WP_002118954.1	signal peptide peptidase SppA	-
C2U64_RS06260 (C2U64_06245)	-	1046195..1046995 (+)	801	WP_002118584.1	alpha/beta fold hydrolase	-
C2U64_RS06265 (C2U64_06250)	purN	1047073..1047702 (-)	630	WP_002118669.1	phosphoribosylglycinamide formyltransferase	-
C2U64_RS06270 (C2U64_06255)	purM	1047699..1048769 (-)	1071	WP_002118876.1	phosphoribosylformylglycinamidine cyclo-ligase	-

Sequence

Protein

• Length: 810 a.a.
• Molecular weight: 92852.37 Da
• Isoelectric Point: 8.9137

>NTDB_id=267016 C2U64_RS06245 WP_002118905.1 1041653..1044085(+) (comA/comEC) [Acinetobacter pittii strain WCHAP005069]
MLKLILMGWIGGIAFMGIDIPLIMQYGWLGKVLLVMGFIFYIFKRNIFLNRPILKTIYCLVCAISLFTIGHQYAQHALNQ
RLELRQMQPKSLDIIVYVDRISDEKEDKTQQPVQVLGQSLHPVNWLLYLKNQKVNSAIDEPKLKLGHYYRISGKTKPAHS
YAVAGVFDQEQWFIQRNIMSGFSVQHIEPLSSDEIYQLGYQHHLKEQQKFFNRQKLNVEKLRLTFRLMLKQSTLQNKGLL
LALLTGDESLLNDEIKNQFKELGISHLLAISGPHVLIFAIMLSWVLHQLIRRYYPQLYLHQPKQIWTMIPLCFGVLIYTA
FVGFEIPALRTLLSVFLFAFLVLIKVAVKPFSLLVYSASLLLLFDPFSALSAGFWLSYGSCFILLRIYQTIEQAPNLVST
SLLSRIILFSKILIESQGKIFIALCPLMLIFFQQITWVAPFTNIIAVPLLGGVIVPLNIFAACVWLIFNSFGNLLFQISD
VLISIVLSCFNLLEKLSLPLQGFSLTPLDLVCLSFVIIILFLPRGVLPKSWGLICCLPLIIPDKSSLQIQLNIIDVGQGQ
SIFLQHPQQTWLIDTGGSYDEKAFSIGRNVVIPYLRQKGIKQLDHVVLSHLDQDHSGAFPSIAQTFPIKQVISNELWKEQ
ITEPFTYCHQGQKWQYPQLDIEILWPKEKDLNLVSTNQNQYSCVIYIHLKQINDYQNYLIMGDAGLEAEYQLMKEYPDLK
VDVLVLGHHGSKHSSAYDFLATLNPKLVVASAGFNNRYGHPSKEVLARIQELNIPFKSTVEQGTLSFVSRNQEMVLYTRR
FERTWLHRNL

Nucleotide

• Length: 2433 bp

>NTDB_id=267016 C2U64_RS06245 WP_002118905.1 1041653..1044085(+) (comA/comEC) [Acinetobacter pittii strain WCHAP005069]
ATGTTAAAACTTATTTTAATGGGGTGGATTGGGGGTATTGCATTTATGGGGATAGATATCCCTTTAATAATGCAATATGG
GTGGTTAGGTAAAGTCTTGCTTGTTATGGGTTTTATTTTTTATATTTTTAAGAGAAATATTTTCTTAAATCGCCCCATAT
TAAAAACCATTTACTGTCTAGTCTGTGCTATTAGTCTCTTTACTATAGGACATCAATATGCTCAGCATGCCTTAAATCAA
AGATTAGAACTGCGACAAATGCAGCCTAAATCTTTAGATATTATTGTGTATGTCGACCGTATAAGTGACGAAAAAGAAGA
TAAGACACAGCAACCCGTTCAGGTATTAGGGCAGTCCTTACATCCCGTTAATTGGCTATTATATTTAAAAAATCAAAAAG
TAAACTCAGCCATAGATGAGCCAAAATTAAAATTAGGTCATTATTATCGAATTTCTGGCAAAACCAAACCTGCTCATAGT
TATGCAGTGGCTGGTGTTTTTGACCAAGAACAGTGGTTCATTCAACGAAATATAATGTCTGGTTTTAGTGTTCAGCATAT
TGAGCCTTTAAGCTCTGATGAAATTTATCAGTTGGGTTATCAACATCATTTAAAAGAGCAACAGAAATTCTTTAACAGAC
AAAAATTAAATGTAGAAAAGTTGCGCCTAACGTTTAGATTAATGTTAAAACAATCTACTTTGCAAAATAAAGGACTGTTA
TTAGCTTTATTAACAGGGGATGAAAGTCTCTTAAATGATGAGATTAAAAATCAATTTAAGGAATTAGGAATCTCTCATCT
GTTAGCCATTTCAGGGCCTCATGTACTCATTTTTGCTATCATGTTGTCTTGGGTATTACATCAATTAATAAGACGTTATT
ATCCGCAGCTTTATTTGCATCAACCTAAACAAATTTGGACCATGATTCCATTATGTTTCGGTGTTTTAATTTATACGGCA
TTTGTTGGTTTTGAAATTCCCGCCTTAAGAACTTTACTCTCAGTATTTTTATTTGCTTTTTTGGTATTGATTAAAGTGGC
TGTTAAACCATTTTCACTCTTGGTTTATAGCGCAAGTCTACTTTTACTTTTCGATCCCTTCAGTGCTTTATCCGCAGGTT
TTTGGCTGTCTTATGGTTCTTGCTTTATTTTATTACGGATTTATCAAACTATAGAGCAGGCTCCAAATCTTGTTTCAACT
AGTCTGTTATCTAGAATCATTCTTTTCAGTAAAATTTTAATTGAATCTCAAGGCAAAATATTTATTGCCTTATGTCCTCT
AATGTTGATTTTCTTTCAACAGATTACATGGGTTGCTCCTTTTACAAATATTATTGCAGTTCCTTTACTCGGAGGAGTGA
TTGTTCCTTTAAATATTTTTGCAGCTTGTGTATGGCTTATTTTTAACTCATTCGGAAATTTACTTTTTCAAATTAGTGAC
GTCCTGATTAGTATAGTACTGTCATGTTTTAATCTTTTAGAAAAGTTATCTCTACCATTACAAGGTTTTAGCCTCACACC
ACTTGATTTAGTGTGCCTTAGCTTCGTTATTATTATCTTATTTTTACCGCGTGGGGTTTTACCCAAATCTTGGGGGCTAA
TATGCTGTTTACCCTTGATCATTCCAGATAAGTCGTCCCTGCAAATTCAATTAAATATTATAGATGTAGGACAGGGGCAA
TCTATATTCTTACAGCACCCGCAGCAGACATGGCTCATCGATACGGGTGGGTCTTATGACGAGAAAGCTTTTAGTATTGG
TCGAAATGTGGTGATTCCATATTTACGCCAAAAGGGAATTAAACAACTGGATCACGTCGTACTATCTCATCTTGATCAAG
ATCATAGCGGAGCATTTCCTTCTATTGCTCAGACTTTTCCTATTAAACAAGTCATATCAAATGAATTATGGAAAGAGCAA
ATTACAGAACCATTTACTTATTGTCATCAAGGGCAAAAATGGCAATATCCACAATTAGATATTGAAATTCTTTGGCCTAA
AGAAAAAGATTTAAACTTAGTTTCTACAAATCAAAATCAATATTCTTGTGTGATTTATATTCATTTAAAACAGATAAATG
ACTATCAAAATTATTTAATCATGGGCGATGCAGGGTTGGAAGCAGAATATCAACTCATGAAAGAATATCCTGATTTAAAG
GTGGATGTCTTGGTATTAGGTCATCATGGAAGTAAACATAGTTCAGCTTACGACTTCTTAGCGACGTTAAACCCCAAGCT
TGTTGTTGCTTCTGCTGGCTTTAATAATCGTTATGGTCATCCAAGCAAAGAGGTTTTAGCGAGAATACAAGAGCTTAATA
TTCCATTTAAAAGCACAGTTGAGCAAGGAACATTGAGTTTTGTATCTCGCAATCAAGAGATGGTTTTATACACTCGACGT
TTCGAGCGTACTTGGCTTCACAGGAATTTGTGA

Domains

Predicted by InterproScan.

• Domain of unknown function (DUF4131) (DUF4131) (28-188)

• Metallo-beta-lactamase superfamily (Lactamase_B) (555-643)

• Competence protein (Competence) (243-522)

3D structure

• AlphaFold DB: A0A009N350

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA/comEC	Acinetobacter baumannii D1279779	68.85	99.877	0.688
comA/comEC	Acinetobacter baumannii strain A118	68.232	99.877	0.681
comA/comEC	Acinetobacter baylyi ADP1	48.708	100	0.489