Detailed information    

insolico Bioinformatically predicted

Overview

Name   amiA   Type   Regulator
Locus tag   SPD_RS07220 Genome accession   NC_008533
Coordinates   1371042..1373000 (-) Length   652 a.a.
NCBI ID   WP_000748873.1    Uniprot ID   A0A0B7M1B9
Organism   Streptococcus pneumoniae D39     
Function   internalize XIP (predicted from homology)   
Competence regulation

Genomic Context

Location: 1366042..1378000
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPD_RS07195 (SPD_1352) - 1366761..1367927 (-) 1167 WP_000521362.1 MalY/PatB family protein -
  SPD_RS07200 (SPD_1353) - 1367935..1369029 (-) 1095 WP_000031966.1 cystathionine gamma-synthase -
  SPD_RS07205 - 1369187..1369910 (-) 724 Protein_1365 ABC transporter ATP-binding protein -
  SPD_RS07210 (SPD_1356) - 1369935..1370870 (-) 936 Protein_1366 ABC transporter ATP-binding protein -
  SPD_RS07220 (SPD_1357) amiA 1371042..1373000 (-) 1959 WP_000748873.1 peptide ABC transporter substrate-binding protein Regulator
  SPD_RS07225 (SPD_1358) - 1373203..1374825 (-) 1623 WP_000017793.1 putative polysaccharide biosynthesis protein -
  SPD_RS07230 (SPD_1359) - 1374931..1376376 (+) 1446 WP_000590294.1 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase -
  SPD_RS07235 (SPD_1360) - 1376422..1376616 (-) 195 WP_000051195.1 CsbD family protein -
  SPD_RS07240 (SPD_1361) - 1376717..1377365 (-) 649 Protein_1371 DUF1803 domain-containing protein -
  SPD_RS07245 (SPD_1362) - 1377349..1377861 (-) 513 WP_000892258.1 YiiX/YebB-like N1pC/P60 family cysteine hydrolase -

Sequence

Protein


Download         Length: 652 a.a.        Molecular weight: 72561.97 Da        Isoelectric Point: 4.9968

>NTDB_id=26695 SPD_RS07220 WP_000748873.1 1371042..1373000(-) (amiA) [Streptococcus pneumoniae D39]
MKKSKSKYLTLAGLVLGTGVLLSACGNSSTASKTYNYVYSSDPSSLNYLAENRAATSDIVANLVDGLLENDQYGNIIPSL
AEDWTVSQDGLTYTYKLRKDAKWFTSEGEEYAPVTAQDFVTGLQYAADKKSEALYLVQDSVAGLDDYITGKTSDFSTVGV
KALDDQTVQYTLVKPELYWNSKTLATILFPVNADFLKSKGDDFGKADPSSILYNGPFLMKALVSKSAIEYKKNPNYWDAK
NVFVDDVKLTYYDGSDQESLERNFTAGAYTTARLFPNSSSYEGIKEKYKNNIIYSMQNSTSYFFNFNLDRKSYNYTSKTS
DIEKKSTQEAVLNKNFRQAINFAFDRTSYGAQSEGKEGATKILRNLVVPPNFVSIKGKDFGEVVASKMVNYGKEWQGINF
ADGQDPYYNPEKAKAKFAEAKKELEAKGVQFPIHLDKTVEVTDKVGIQGVSSIKQSIESVLGSDNVVIDIQQLTSDEFDS
SGYFAQTAAQKDYDLYHGGWGPDYQDPSTYLDIFNTNSGGFLQNLGLEPGEANDKAKAVGLDVYTQMLEEANKEQDPAKR
YEKYADIQAWLIDSSLVLPSVSRGGTPSLRRTVPFAAAYGLTGTKGVESYKYLKVQDKIVTTDEYAKAREKWLKEKEESN
KKAQEELAKHVK

Nucleotide


Download         Length: 1959 bp        

>NTDB_id=26695 SPD_RS07220 WP_000748873.1 1371042..1373000(-) (amiA) [Streptococcus pneumoniae D39]
ATGAAAAAGTCTAAGAGCAAATATCTAACCTTGGCAGGTCTTGTCCTGGGTACAGGAGTTTTATTGAGCGCGTGTGGAAA
TTCTAGCACTGCATCAAAAACCTATAACTATGTTTATTCAAGTGATCCATCTAGTTTGAACTATCTAGCAGAAAACCGCG
CAGCAACATCCGATATTGTTGCAAATTTGGTAGACGGGTTATTAGAAAATGACCAATATGGGAATATTATTCCATCATTA
GCAGAGGATTGGACTGTTTCTCAGGACGGTTTGACCTATACCTACAAACTTCGTAAGGATGCCAAGTGGTTTACTTCTGA
GGGAGAAGAATATGCGCCTGTAACTGCCCAGGATTTTGTGACAGGTTTGCAATATGCAGCTGATAAAAAATCAGAAGCTT
TGTATCTAGTGCAGGACTCTGTTGCTGGTTTGGATGACTATATCACTGGTAAAACAAGCGACTTTTCAACTGTCGGTGTC
AAGGCACTTGATGACCAAACGGTTCAATATACTTTGGTTAAACCAGAACTTTACTGGAATTCAAAAACACTTGCAACGAT
ACTTTTTCCTGTTAATGCAGATTTCCTGAAATCAAAAGGGGATGATTTTGGGAAGGCGGATCCATCTAGTATTTTGTACA
ATGGACCTTTCTTAATGAAAGCACTTGTCTCAAAATCTGCTATTGAATATAAGAAAAACCCTAATTACTGGGATGCTAAG
AATGTCTTTGTAGACGATGTGAAATTGACCTACTATGATGGTAGCGACCAAGAATCACTGGAACGTAATTTTACAGCTGG
TGCTTATACTACGGCTCGTCTTTTTCCTAACAGCTCCAGCTATGAAGGGATTAAAGAAAAATACAAAAACAATATCATCT
ATAGTATGCAAAATTCAACTTCATATTTCTTTAATTTTAACCTAGATAGGAAGTCTTACAATTATACTTCTAAAACAAGT
GACATTGAAAAGAAATCGACTCAGGAAGCAGTTCTCAATAAAAACTTCCGTCAGGCTATCAATTTTGCTTTTGACAGAAC
ATCTTATGGGGCTCAGTCTGAAGGGAAAGAAGGTGCAACAAAGATTTTGCGTAACCTAGTGGTTCCTCCAAACTTTGTCA
GTATCAAGGGAAAAGACTTTGGTGAAGTTGTAGCCTCTAAGATGGTCAACTATGGTAAGGAATGGCAAGGTATCAACTTT
GCGGATGGTCAAGACCCTTACTACAATCCTGAGAAAGCCAAGGCTAAGTTTGCGGAAGCTAAGAAAGAACTCGAAGCAAA
GGGTGTTCAATTCCCAATCCACTTGGATAAGACTGTGGAAGTAACAGATAAAGTAGGCATACAAGGAGTTAGTTCTATCA
AACAATCAATTGAATCTGTTTTAGGTTCTGATAATGTAGTGATTGACATTCAGCAATTAACATCAGATGAGTTTGACAGT
TCAGGCTACTTTGCTCAAACAGCTGCTCAGAAAGACTATGATTTATATCATGGCGGTTGGGGACCTGATTATCAAGACCC
GTCAACCTATCTCGATATTTTTAATACTAATAGTGGAGGATTTCTGCAAAATCTTGGACTAGAGCCTGGTGAGGCCAATG
ACAAGGCTAAGGCAGTTGGACTGGATGTCTATACTCAAATGTTGGAAGAAGCTAATAAAGAACAAGATCCAGCCAAACGT
TATGAGAAATATGCTGATATTCAAGCTTGGTTGATTGATAGTTCTTTAGTTCTTCCAAGTGTTTCGCGTGGGGGAACACC
ATCATTGAGAAGAACCGTACCATTTGCTGCTGCCTATGGTTTAACCGGTACAAAAGGGGTTGAATCATATAAATACCTCA
AAGTACAAGATAAGATTGTCACAACAGACGAATATGCAAAAGCTAGAGAAAAATGGTTGAAAGAAAAAGAAGAATCCAAT
AAAAAAGCCCAAGAAGAATTGGCAAAACATGTCAAATAA

Domains

Predicted by InterproScan.

Bacterial extracellular solute-binding proteins, family 5 Middle (SBP_bac_5)

(76-519)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0B7M1B9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  amiA Streptococcus salivarius strain HSISS4

56.422

100

0.566
  amiA3 Streptococcus thermophilus LMD-9

55.878

100

0.561
  amiA3 Streptococcus thermophilus LMG 18311

55.725

100

0.56

Multiple sequence alignment