Detailed information NTG0266869

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: RK70_RS10720
• Genome accession: NZ_CP026080
• Coordinates: 2107531..2108418 (+)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain FDAARGOS_12
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2102531..2113418

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RK70_RS10690 (RK70_010690)	-	2103263..2104024 (+)	762	WP_000323455.1	alpha/beta hydrolase family protein	-
RK70_RS10695 (RK70_010695)	-	2104269..2104724 (+)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
RK70_RS14285 (RK70_010700)	-	2104846..2104947 (+)	102	WP_000731972.1	SE2200 family small protein	-
RK70_RS10705 (RK70_010705)	-	2105007..2106431 (-)	1425	WP_000953744.1	alkaline phosphatase	-
RK70_RS10710 (RK70_010710)	-	2106629..2106829 (+)	201	WP_000604728.1	hypothetical protein	-
RK70_RS10715 (RK70_010715)	braR	2106855..2107520 (+)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
RK70_RS10720 (RK70_010720)	braS	2107531..2108418 (+)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
RK70_RS10725 (RK70_010725)	-	2108526..2109281 (+)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
RK70_RS10730 (RK70_010730)	-	2109278..2111278 (+)	2001	WP_000776751.1	ABC transporter permease	-
RK70_RS10735 (RK70_010735)	-	2111937..2112050 (+)	114	WP_011447078.1	hypothetical protein	-
RK70_RS10745 (RK70_010745)	-	2112432..2112692 (+)	261	WP_001789910.1	hypothetical protein	-
RK70_RS10750 (RK70_010750)	-	2112702..2113199 (+)	498	WP_001065268.1	glutathione peroxidase	-
RK70_RS10755 (RK70_010755)	-	2113307..2113399 (-)	93	WP_010956583.1	hypothetical protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=266869 RK70_RS10720 WP_000143419.1 2107531..2108418(+) (braS) [Staphylococcus aureus strain FDAARGOS_12]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=266869 RK70_RS10720 WP_000143419.1 2107531..2108418(+) (braS) [Staphylococcus aureus strain FDAARGOS_12]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997