Detailed information NTG0266445

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: RK82_RS07170
• Genome accession: NZ_CP026068
• Coordinates: 1393056..1394099 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain FDAARGOS_24
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1388056..1399099

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RK82_RS07140 (RK82_007140)	-	1388474..1389730 (-)	1257	WP_001795438.1	aminopeptidase	-
RK82_RS07145 (RK82_007145)	-	1389733..1389933 (-)	201	WP_000180461.1	DUF1128 family protein	-
RK82_RS07150 (RK82_007150)	-	1390080..1390544 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
RK82_RS07155 (RK82_007155)	-	1390551..1390826 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
RK82_RS07160 (RK82_007160)	-	1391104..1392321 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
RK82_RS07165 (RK82_007165)	vraR	1392437..1393066 (-)	630	WP_000153530.1	two-component system response regulator VraR	Regulator
RK82_RS07170 (RK82_007170)	vraS	1393056..1394099 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
RK82_RS07175 (RK82_007175)	liaF	1394096..1394797 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
RK82_RS07180 (RK82_007180)	-	1394812..1395198 (-)	387	WP_001110179.1	hypothetical protein	-
RK82_RS07185 (RK82_007185)	map	1395415..1396173 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
RK82_RS07200 (RK82_007200)	-	1396701..1397687 (+)	987	WP_000999713.1	aromatic acid exporter family protein	-
RK82_RS07210 (RK82_007210)	-	1398118..1398531 (-)	414	WP_001549145.1	hypothetical protein	-
RK82_RS07215 (RK82_007215)	-	1398560..1398670 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=266445 RK82_RS07170 WP_001017131.1 1393056..1394099(-) (vraS) [Staphylococcus aureus strain FDAARGOS_24]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=266445 RK82_RS07170 WP_001017131.1 1393056..1394099(-) (vraS) [Staphylococcus aureus strain FDAARGOS_24]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTTTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
TATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1