Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrB   Type   Machinery gene
Locus tag   DY328_RS00780 Genome accession   NZ_CP031556
Coordinates   158089..160080 (-) Length   663 a.a.
NCBI ID   WP_000567072.1    Uniprot ID   Q8DYL6
Organism   Streptococcus agalactiae strain Sag27     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 153089..165080
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DY328_RS00755 (DY328_00755) - 154173..154820 (-) 648 WP_002403315.1 type A-8 chloramphenicol O-acetyltransferase -
  DY328_RS00760 (DY328_00760) - 154955..155266 (-) 312 Protein_147 replication initiation protein -
  DY328_RS00770 (DY328_00770) tet 155861..157105 (-) 1245 Protein_148 Tet(L)/Tet(K)/Tet(45) family tetracycline efflux MFS transporter -
  DY328_RS00775 (DY328_00775) - 157181..157861 (+) 681 WP_001015311.1 IS6-like element IS1216 family transposase -
  DY328_RS00780 (DY328_00780) uvrB 158089..160080 (-) 1992 WP_000567072.1 excinuclease ABC subunit UvrB Machinery gene
  DY328_RS00785 (DY328_00785) - 160141..161061 (-) 921 WP_001042316.1 CPBP family intramembrane glutamic endopeptidase -
  DY328_RS00790 (DY328_00790) - 161244..163427 (+) 2184 WP_000681005.1 ABC transporter substrate-binding protein/permease -
  DY328_RS00795 (DY328_00795) - 163427..164167 (+) 741 WP_000818887.1 amino acid ABC transporter ATP-binding protein -
  DY328_RS00800 (DY328_00800) - 164316..164666 (+) 351 WP_000656279.1 hypothetical protein -
  DY328_RS00805 (DY328_00805) - 164758..164916 (-) 159 WP_000502594.1 hypothetical protein -

Sequence

Protein


Download         Length: 663 a.a.        Molecular weight: 76016.94 Da        Isoelectric Point: 4.6430

>NTDB_id=266318 DY328_RS00780 WP_000567072.1 158089..160080(-) (uvrB) [Streptococcus agalactiae strain Sag27]
MIDRKDTNRFKLVSKYSPSGDQPQAIETLVDNIEGGEKAQILKGATGTGKTYTMSQVIAQVNKPTLVIAHNKTLAGQLYG
EFKEFFPDNAVEYFVSYYDYYQPEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVVASVSCIYGLGSPKEYA
DSVVSLRPGQEISRDQLLNNLVDIQFERNDIDFQRGKFRVRGDVVEVFPASRDEHAFRIEFFGDEIDRIREIESLTGRVL
GEVEHLAIFPATHFMTNDEHMEEAISKIQAEMENQVELFEKEGKLIEAQRIRQRTEYDIEMLREMGYTNGVENYSRHMDG
RSEGEPPFTLLDFFPEDFLIMIDESHMTMGQIKGMYNGDRSRKEMLVNYGFRLPSALDNRPLRREEFESHVHQIVYVSAT
PGDYEMEQTDTVVEQIIRPTGLLDPEVEVRPSMGQMDDLLGEINLRTEKGERTFITTLTKRMAEDLTDYLKEMGVKVKYM
HSDIKTLERTEIIRDLRLGVFDVLIGINLLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSNGHVIMYADK
ITDSMQRAMDETARRRRLQMDYNEKHGIVPQTIKKEIRDLIAITKSNDSDKPEKVVDYSSLSKKERQAEIKALQQQMQEA
AELLDFELAAQIRDVILELKAID

Nucleotide


Download         Length: 1992 bp        

>NTDB_id=266318 DY328_RS00780 WP_000567072.1 158089..160080(-) (uvrB) [Streptococcus agalactiae strain Sag27]
ATGATAGATAGAAAAGATACTAACCGATTTAAATTAGTTTCCAAATATAGCCCTTCGGGAGATCAACCTCAAGCTATTGA
AACGTTGGTTGACAATATTGAAGGAGGAGAAAAAGCTCAGATTTTAAAAGGTGCTACTGGTACTGGTAAAACCTACACAA
TGAGCCAAGTTATCGCCCAAGTTAACAAGCCAACCTTGGTGATTGCACATAATAAAACCTTAGCAGGTCAACTTTATGGA
GAGTTTAAAGAATTTTTTCCTGACAATGCCGTAGAGTACTTTGTTTCATATTATGATTATTATCAACCAGAAGCTTATGT
GCCTTCTTCGGATACTTATATTGAAAAAGATAGTTCAGTCAATGACGAAATTGACAAATTACGTCACTCAGCGACTTCTT
CGTTATTAGAAAGAAATGACGTTATTGTTGTAGCATCTGTTTCTTGTATTTACGGTTTAGGTTCTCCTAAAGAGTATGCA
GACAGTGTTGTTAGCCTTAGGCCAGGTCAAGAAATTTCACGTGATCAGTTATTGAACAATCTCGTTGATATTCAATTTGA
GCGTAACGATATTGATTTTCAACGTGGAAAATTTCGCGTTCGTGGCGATGTTGTAGAAGTTTTTCCTGCGAGTCGTGATG
AGCATGCCTTTCGAATTGAATTTTTTGGTGATGAAATTGATCGTATAAGAGAAATAGAATCGTTAACAGGGCGTGTGCTA
GGAGAAGTGGAACATTTAGCTATTTTCCCAGCAACACACTTTATGACAAATGATGAACATATGGAAGAAGCTATTTCAAA
AATACAAGCTGAAATGGAAAATCAAGTAGAACTTTTTGAAAAAGAAGGGAAATTGATTGAAGCGCAACGTATTCGACAAA
GGACAGAATATGATATTGAAATGCTTCGTGAAATGGGATATACAAATGGTGTTGAGAACTACTCACGTCACATGGATGGT
AGAAGTGAAGGTGAGCCACCTTTTACTTTGTTAGATTTCTTCCCAGAAGATTTTTTGATTATGATTGATGAGAGTCACAT
GACAATGGGGCAAATCAAAGGGATGTATAATGGAGACCGTTCGCGTAAAGAAATGTTGGTTAATTACGGTTTCCGTTTAC
CATCTGCCTTAGATAACCGTCCACTTCGTCGTGAAGAATTCGAAAGCCATGTCCATCAAATTGTCTATGTATCTGCAACG
CCAGGAGACTATGAAATGGAGCAAACAGATACAGTTGTTGAGCAAATTATCCGGCCAACAGGACTTCTTGATCCAGAAGT
TGAAGTTAGACCAAGTATGGGGCAGATGGATGACTTGCTTGGTGAAATCAATTTGAGGACTGAAAAAGGTGAGCGTACCT
TTATTACAACATTGACAAAGCGTATGGCAGAAGACTTAACAGATTATCTCAAAGAAATGGGAGTTAAAGTTAAGTATATG
CACAGCGATATTAAAACCTTAGAACGTACAGAGATTATTCGTGATTTACGACTTGGTGTGTTTGATGTTTTAATTGGTAT
TAATCTCTTACGTGAAGGAATAGATGTTCCTGAGGTTTCCCTTGTTGCAATCTTAGATGCTGATAAGGAAGGTTTCCTTC
GTAATGAGCGTGGTCTTATCCAAACAATCGGACGTGCAGCACGTAACAGTAATGGTCATGTTATTATGTATGCTGATAAA
ATAACAGATTCTATGCAAAGAGCTATGGATGAAACCGCTCGCCGTCGTCGTTTACAAATGGATTATAATGAAAAGCATGG
AATTGTGCCACAAACAATTAAAAAAGAAATCCGTGATTTAATTGCTATTACTAAAAGTAATGACAGCGATAAGCCTGAAA
AAGTTGTCGATTACAGTAGTTTATCTAAAAAAGAAAGGCAAGCTGAAATTAAAGCTCTTCAACAGCAAATGCAAGAAGCA
GCTGAATTATTGGACTTTGAGCTAGCTGCACAAATCCGAGATGTTATCTTAGAACTAAAAGCAATCGATTAA

Domains

Predicted by InterProScan.

Ultra-violet resistance protein B (UvrB)

(556-598)

Helicase conserved C-terminal domain (Helicase_C)

(446-549)

UvrB/uvrC motif (UVR)

(628-661)

Type III restriction enzyme, res subunit (ResIII)

(20-143)

UvrB interaction domain (UvrB_inter)

(164-254)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q8DYL6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrB Streptococcus pneumoniae R6

87.179

100

0.872
  uvrB Streptococcus pneumoniae D39

87.179

100

0.872
  uvrB Streptococcus pneumoniae TIGR4

87.029

100

0.87