Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   DS732_RS26720 Genome accession   NZ_CP031546
Coordinates   5152170..5152760 (-) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain cq9     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 5147170..5157760
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DS732_RS26705 (DS732_26705) uhpT 5147810..5149201 (-) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -
  DS732_RS26710 (DS732_26710) uhpC 5149339..5150658 (-) 1320 WP_000936566.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  DS732_RS26715 (DS732_26715) uhpB 5150668..5152170 (-) 1503 WP_001295243.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  DS732_RS26720 (DS732_26720) letA 5152170..5152760 (-) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  DS732_RS26725 (DS732_26725) ilvN 5152835..5153125 (-) 291 WP_001181706.1 acetolactate synthase small subunit -
  DS732_RS26730 (DS732_26730) ilvB 5153129..5154817 (-) 1689 WP_000168480.1 acetolactate synthase large subunit -
  DS732_RS26735 (DS732_26735) ivbL 5154923..5155021 (-) 99 WP_001315912.1 ilvB operon leader peptide IvbL -
  DS732_RS26755 (DS732_26755) tisB 5155586..5155675 (+) 90 WP_000060506.1 type I toxin-antitoxin system toxin TisB -
  DS732_RS32165 ysdE 5155938..5156012 (-) 75 WP_211180519.1 protein YsdE -
  DS732_RS26765 (DS732_26765) emrD 5156094..5157278 (+) 1185 WP_063103062.1 multidrug efflux MFS transporter EmrD -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=266313 DS732_RS26720 WP_000633668.1 5152170..5152760(-) (letA) [Escherichia coli strain cq9]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=266313 DS732_RS26720 WP_000633668.1 5152170..5152760(-) (letA) [Escherichia coli strain cq9]
ATGATCACCGTTGCCCTTATAGACGATCACCTCATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCCGATATCTCCGGTCTGGAACTGCTAAGCCAGCTGCCGAAAGGTATGGCGACAATAATGCTCTCTGTT
CATGACAGTCCGGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCACGCGGCTTTCTCTCCAAACGCTGTAGCCCTGACGA
ACTGATTGCGGCGGTGCATACGGTTGCCACGGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GTCAGGACCCGCTAACCAAACGCGAACGGCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCTGCC
GAACTGGGCTTGTCGCCGAAAACGGTGCACGTCCATCGCGCCAACCTGATGGAAAAACTGGGTGTCAGTAACGACGTAGA
GCTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378

Multiple sequence alignment