Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrB   Type   Machinery gene
Locus tag   LR49_RS12450 Genome accession   NZ_CP031537
Coordinates   2376552..2378537 (+) Length   661 a.a.
NCBI ID   WP_000229253.1    Uniprot ID   A0A0H2XGZ8
Organism   Staphylococcus aureus strain WCH-SK2     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 2371552..2383537
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LR49_RS12420 (LR49_12420) - 2372595..2372699 (+) 105 WP_001790092.1 hypothetical protein -
  LR49_RS12425 (LR49_12425) prfB 2372868..2373978 (+) 1111 WP_010956549.1 peptide chain release factor 2 -
  LR49_RS12430 (LR49_12430) - 2374132..2374239 (+) 108 WP_001790093.1 hypothetical protein -
  LR49_RS12435 (LR49_12435) - 2374387..2375226 (+) 840 WP_000749380.1 CHAP domain-containing protein -
  LR49_RS12440 (LR49_12440) - 2375400..2376050 (+) 651 WP_000538141.1 YfbR-like 5'-deoxynucleotidase -
  LR49_RS12445 (LR49_12445) - 2376047..2376283 (+) 237 WP_000638419.1 CsbA family protein -
  LR49_RS12450 (LR49_12450) uvrB 2376552..2378537 (+) 1986 WP_000229253.1 excinuclease ABC subunit UvrB Machinery gene
  LR49_RS12455 (LR49_12455) uvrA 2378545..2381391 (+) 2847 WP_000662681.1 excinuclease ABC subunit UvrA Machinery gene
  LR49_RS12460 (LR49_12460) hprK 2382053..2382985 (+) 933 WP_000958224.1 HPr(Ser) kinase/phosphatase -

Sequence

Protein


Download         Length: 661 a.a.        Molecular weight: 76648.34 Da        Isoelectric Point: 5.0538

>NTDB_id=266102 LR49_RS12450 WP_000229253.1 2376552..2378537(+) (uvrB) [Staphylococcus aureus strain WCH-SK2]
MVEHYPFKIHSDFEPQGDQPQAIKEIVEGIKAGKRHQTLLGATGTGKTFTMSNVIKEVGKPTLIIAHNKTLAGQLYSEFK
EFFPENRVEYFVSYYDYYQPEAYVPSTDTFIEKDASINDEIDQLRHSATSALFERDDVIIIASVSCIYGLGNPEEYKDLV
VSVRVGMEMDRSELLRKLVDVQYTRNDIDFQRGTFRVRGDVVEIFPASKEELCIRVEFFGDEIDRIREVNYLTGEVLKER
EHFAIFPASHFVTREEKLKVAIERIEKELEERLKELRDENKLLEAQRLEQRTNYDLEMMREMGFCSGIENYSVHLTLRPL
GSTPYTLLDYFGDDWLVMIDESHVTLPQVRGMYNGDRARKQVLVDHGFRLPSALDNRPLKFEEFEEKTKQLVYVSATPGP
YEIEHTDKMVEQIIRPTGLLDPKIEVRPTENQIDDLLSEIQTRVERNERVLVTTLTKKMSEDLTTYMKEAGIKVNYLHSE
IKTLERIEIIRDLRMGTYDVIVGINLLREGIDIPEVSLVVILDADKEGFLRSNRSLIQTIGRAARNDKGEVIMYADKMTD
SMKYAIDETQRRREIQMKHNEKHGITPKTINKKIHDLISATVENDENNDKAQTVIPKKMTKKERQKTIDNIEKEMKQAAK
DLDFEKATELRDMLFELKAEG

Nucleotide


Download         Length: 1986 bp        

>NTDB_id=266102 LR49_RS12450 WP_000229253.1 2376552..2378537(+) (uvrB) [Staphylococcus aureus strain WCH-SK2]
ATGGTTGAACATTATCCTTTTAAAATACATTCTGATTTTGAGCCTCAAGGTGACCAACCGCAAGCAATTAAAGAAATCGT
GGAAGGTATTAAAGCGGGGAAAAGACATCAAACTTTATTAGGTGCTACTGGCACAGGGAAAACATTTACGATGAGTAATG
TTATTAAAGAAGTTGGGAAACCAACGTTAATTATCGCGCATAACAAAACATTAGCAGGACAATTATATAGTGAGTTTAAA
GAATTTTTTCCTGAAAACAGGGTGGAATACTTTGTAAGTTACTATGATTATTATCAACCAGAGGCATACGTACCGTCTAC
TGACACTTTTATTGAAAAAGATGCCTCAATCAATGATGAAATTGATCAACTACGACATTCTGCTACAAGTGCATTATTTG
AACGCGATGATGTAATTATTATTGCTAGTGTAAGTTGTATATATGGTTTAGGTAATCCTGAAGAATATAAAGATTTAGTA
GTAAGTGTTCGAGTTGGTATGGAAATGGATAGAAGTGAATTACTTAGAAAACTTGTAGATGTGCAATATACACGAAATGA
CATCGATTTCCAACGAGGAACGTTTCGAGTGCGTGGTGATGTAGTGGAAATATTCCCAGCCTCTAAAGAAGAACTTTGTA
TAAGGGTTGAGTTTTTCGGCGATGAGATTGACCGTATCCGAGAAGTTAACTACCTAACAGGTGAAGTGTTGAAAGAAAGA
GAACATTTTGCGATATTCCCAGCTTCTCACTTCGTAACACGTGAAGAAAAGTTGAAAGTTGCGATTGAACGTATTGAAAA
AGAATTGGAAGAACGATTGAAAGAATTACGAGATGAGAATAAATTACTAGAAGCGCAAAGGTTAGAACAGCGTACCAACT
ATGATTTAGAAATGATGCGAGAGATGGGATTCTGTTCAGGAATTGAAAACTATTCCGTACATTTAACTTTGCGACCACTG
GGTTCGACACCATATACTTTATTGGATTACTTTGGCGATGATTGGTTAGTAATGATTGATGAATCACATGTGACATTACC
GCAAGTTCGAGGCATGTATAACGGAGACAGAGCGCGTAAACAAGTTTTGGTGGATCATGGGTTTAGATTACCGAGTGCAT
TAGATAACCGTCCACTTAAATTTGAAGAATTTGAAGAAAAGACAAAACAACTTGTGTATGTATCTGCAACGCCTGGACCA
TACGAAATTGAACATACGGATAAGATGGTTGAACAAATTATTCGTCCTACTGGTTTACTGGATCCTAAGATTGAGGTTAG
ACCTACTGAAAATCAAATTGACGATTTATTAAGTGAAATTCAAACAAGAGTTGAGCGTAATGAACGCGTACTTGTTACAA
CGCTCACTAAAAAGATGAGTGAAGATTTAACCACATACATGAAAGAAGCGGGTATTAAAGTTAATTATCTGCATTCAGAA
ATCAAGACATTAGAACGAATTGAAATAATTAGAGACTTACGAATGGGTACATATGATGTTATCGTAGGTATTAATTTATT
AAGAGAGGGTATTGATATACCAGAAGTTTCTCTAGTTGTCATATTAGATGCAGATAAAGAAGGGTTTTTACGTTCTAACC
GCTCATTAATTCAAACAATAGGTAGAGCTGCGCGTAACGATAAAGGTGAAGTCATTATGTATGCCGATAAAATGACTGAT
TCGATGAAGTATGCAATTGATGAGACACAACGTCGTCGAGAAATACAGATGAAACATAATGAAAAACATGGTATTACACC
TAAAACAATTAATAAAAAAATACATGATTTAATTAGTGCTACTGTTGAAAATGACGAAAATAATGACAAAGCACAAACTG
TGATACCTAAGAAGATGACGAAAAAAGAACGTCAAAAGACAATCGACAATATAGAAAAAGAAATGAAACAAGCAGCGAAA
GATTTAGATTTCGAGAAAGCTACAGAATTAAGAGATATGTTATTTGAATTAAAAGCAGAAGGGTGA

Domains

Predicted by InterProScan.

Helicase conserved C-terminal domain (Helicase_C)

(434-546)

Ultra-violet resistance protein B (UvrB)

(553-594)

Type III restriction enzyme, res subunit (ResIII)

(14-140)

UvrB/uvrC motif (UVR)

(626-659)

UvrB interaction domain (UvrB_inter)

(161-251)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2XGZ8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrB Streptococcus pneumoniae R6

67.534

98.79

0.667
  uvrB Streptococcus pneumoniae TIGR4

67.534

98.79

0.667
  uvrB Streptococcus pneumoniae D39

67.534

98.79

0.667