Detailed information NTG0265663

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: C2H95_RS00165
• Genome accession: NZ_CP026037
• Coordinates: 29369..30526 (-)
• Length: 385 a.a.
• NCBI ID: WP_003227983.1
• Uniprot ID: A0A199WDV9
• Organism: Bacillus subtilis strain PK5_17
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 24369..35526

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
C2H95_RS00135 (C2H95_00135)	yvyF	24623..25042 (-)	420	WP_003227995.1	TIGR03826 family flagellar region protein	-
C2H95_RS00140 (C2H95_00140)	comFC	25115..25837 (-)	723	WP_014481051.1	comF operon protein ComFC	Machinery gene
C2H95_RS00145 (C2H95_00145)	comFB	25801..26097 (-)	297	WP_003227989.1	late competence protein ComFB	-
C2H95_RS00150 (C2H95_00150)	comFA	26157..27548 (-)	1392	WP_014481052.1	ATP-dependent helicase ComFA	Machinery gene
C2H95_RS00155 (C2H95_00155)	fakBA	27654..28499 (-)	846	WP_085185615.1	DegV family protein	-
C2H95_RS00160 (C2H95_00160)	degU	28597..29286 (-)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
C2H95_RS00165 (C2H95_00165)	degS	29369..30526 (-)	1158	WP_003227983.1	two-component sensor histidine kinase DegS	Regulator
C2H95_RS00170 (C2H95_00170)	yvyE	30743..31396 (+)	654	WP_003227979.1	YigZ family protein	-
C2H95_RS00175 (C2H95_00175)	tagV	31396..32562 (+)	1167	WP_220396509.1	polyisoprenyl-teichoic acid--peptidoglycan teichoic acid transferase TagV	-
C2H95_RS00180 (C2H95_00180)	tagO	32635..33711 (-)	1077	WP_003227975.1	MraY family glycosyltransferase	-
C2H95_RS00185 (C2H95_00185)	tuaH	33856..35049 (-)	1194	WP_103803439.1	glycosyltransferase family 1 protein	-

Sequence

Protein

• Length: 385 a.a.
• Molecular weight: 44957.76 Da
• Isoelectric Point: 6.2957

>NTDB_id=265663 C2H95_RS00165 WP_003227983.1 29369..30526(-) (degS) [Bacillus subtilis strain PK5_17]
MNKTKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVQTRHARNRLSEVSR
NFHRFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLREVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGAEDGFQEIKNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGETEDQRLAPQFEVALFRLAQEAVSNALKHSESEEITVKVEI
TKDFVILMIKDNGKGFDLKEAKEKKNKSFGLLGMKERVDLLEGTMTIDSKIGLGTFIMIKVPLSL

Nucleotide

• Length: 1158 bp

>NTDB_id=265663 C2H95_RS00165 WP_003227983.1 29369..30526(-) (degS) [Bacillus subtilis strain PK5_17]
ATGAATAAAACAAAGATGGATTCCAAAGTGCTGGATTCTATTTTGATGAAGATGCTGAAAACCGTTGACGGGAGCAAGGA
CGAGGTTTTTCAAATCGGGGAGCAGTCACGCCAGCAGTATGAACAGCTGGTCGAAGAACTGAAACAAATTAAACAGCAGG
TGTATGAAGTGATCGAGCTTGGCGATAAACTTGAAGTGCAAACCCGCCATGCGAGAAACCGTTTATCCGAAGTCAGCCGT
AATTTTCATAGATTCAGTGAAGAGGAAATCCGCAATGCTTATGAAAAAGCCCATAAGCTGCAGGTAGAATTGACGATGAT
CCAGCAGCGTGAGAAGCAATTGCGCGAACGGCGGGACGATTTGGAGCGCAGATTGCTAGGGCTTCAGGAAATCATTGAGC
GGTCAGAATCATTAGTAAGCCAAATTACAGTTGTGCTCAACTACTTGAATCAGGATTTGCGCGAAGTTGGACTGCTTCTT
GCCGATGCTCAGGCAAAACAGGATTTCGGATTAAGAATTATTGAGGCGCAGGAAGAAGAGCGAAAAAGAGTCTCAAGAGA
AATCCATGACGGACCCGCTCAAATGCTGGCGAATGTTATGATGAGATCGGAATTAATCGAGCGGATTTTCCGTGACCGGG
GCGCAGAGGACGGATTCCAAGAAATTAAAAATCTACGCCAAAATGTTCGGAATGCCCTTTACGAAGTGAGAAGGATTATA
TATGATTTAAGACCGATGGCCCTTGATGACCTAGGCCTGATTCCAACTTTAAGAAAATATCTATATACAACCGAGGAATA
TAACGGGAAGGTCAAAATACATTTTCAGTGCATTGGAGAAACAGAGGATCAGAGGCTAGCGCCTCAGTTTGAGGTTGCGC
TCTTCAGGCTCGCACAGGAAGCTGTGTCTAATGCGCTAAAGCATTCTGAATCTGAAGAAATTACAGTCAAAGTTGAGATC
ACAAAGGATTTTGTGATTTTAATGATAAAAGATAACGGTAAAGGGTTCGACCTGAAGGAAGCGAAAGAGAAGAAAAACAA
ATCATTCGGCTTGCTGGGCATGAAAGAAAGAGTAGATTTATTGGAAGGAACAATGACAATAGATTCGAAAATAGGTCTTG
GGACATTTATTATGATTAAGGTTCCGTTATCTCTTTGA

Domains

Predicted by InterproScan.

• Histidine kinase (HisKA_3) (180-248)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

3D structure

• AlphaFold DB: A0A199WDV9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	100	100	1