Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   DK878_RS02135 Genome accession   NZ_CP031379
Coordinates   415245..415886 (+) Length   213 a.a.
NCBI ID   WP_002937025.1    Uniprot ID   A0A0H3MTV8
Organism   Streptococcus suis strain ISU2660     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 410245..420886
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DK878_RS02115 (DK878_02195) - 410413..411150 (+) 738 WP_012774983.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  DK878_RS02120 (DK878_02200) stkP 411150..413144 (+) 1995 WP_009909429.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  DK878_RS02125 (DK878_02205) liaF 413601..414260 (+) 660 WP_226964025.1 cell wall-active antibiotics response protein LiaF -
  DK878_RS02130 (DK878_02210) - 414257..415273 (+) 1017 WP_002937028.1 sensor histidine kinase -
  DK878_RS02135 (DK878_02215) vraR 415245..415886 (+) 642 WP_002937025.1 response regulator transcription factor Regulator
  DK878_RS02140 (DK878_02220) - 415936..417336 (+) 1401 WP_002937018.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  DK878_RS02145 (DK878_02225) - 417338..417709 (+) 372 WP_002937017.1 S1 RNA-binding domain-containing protein -
  DK878_RS02150 (DK878_02230) cysK 417736..418662 (-) 927 WP_002937015.1 cysteine synthase A -
  DK878_RS02155 (DK878_02235) - 418892..420049 (-) 1158 WP_013730163.1 site-specific integrase -

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 23790.36 Da        Isoelectric Point: 4.8970

>NTDB_id=265528 DK878_RS02135 WP_002937025.1 415245..415886(+) (vraR) [Streptococcus suis strain ISU2660]
MNTIRVMLVDDHEMVRLGLKSYLNLQPDVEVVAEASDGEEGLAKALEVKPDVVVMDLVMPKMTGVEATLALLKEWPQAQI
VILTSYLDNEKIYPVLEAGARGYMLKTSSADEILAAIRKVALGEYAIETEVEKKVEHHKRHPDLHDDLTAREREILTLLA
KGYDNQRIADESFISLKTVKTHVSNILSKLAVSDRTQAVVYAFQHGLVAQEDQ

Nucleotide


Download         Length: 642 bp        

>NTDB_id=265528 DK878_RS02135 WP_002937025.1 415245..415886(+) (vraR) [Streptococcus suis strain ISU2660]
ATGAATACGATTCGAGTGATGCTGGTTGACGACCATGAGATGGTTCGTCTAGGATTGAAAAGTTACTTAAATTTACAGCC
AGATGTTGAAGTAGTTGCAGAAGCTAGTGATGGCGAGGAAGGTTTGGCTAAAGCATTAGAGGTTAAACCCGATGTTGTAG
TGATGGACTTGGTTATGCCTAAGATGACTGGCGTAGAAGCAACCCTGGCCTTGCTGAAGGAATGGCCGCAAGCGCAGATT
GTCATCCTGACCTCCTACCTAGATAATGAGAAAATCTATCCTGTGCTGGAAGCAGGAGCTCGTGGCTATATGTTGAAAAC
GTCAAGTGCTGACGAAATCTTAGCCGCTATCCGCAAGGTAGCTCTTGGAGAATATGCTATTGAGACAGAAGTAGAGAAAA
AAGTAGAGCACCATAAACGCCACCCAGATTTACATGATGACTTGACAGCTCGTGAACGCGAAATCTTGACGCTGTTAGCC
AAGGGATATGATAATCAACGAATTGCAGATGAGTCTTTCATTTCCCTAAAAACTGTTAAGACCCATGTTTCCAATATCTT
ATCCAAACTAGCTGTTAGCGATCGTACTCAAGCAGTTGTTTATGCTTTCCAGCATGGTTTGGTGGCGCAAGAGGACCAAT
AG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(148-202)

Response regulator receiver domain (Response_reg)

(6-118)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H3MTV8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

54.589

97.183

0.531
  degU Bacillus subtilis subsp. subtilis str. 168

38.938

100

0.413