Detailed information    

insolico Bioinformatically predicted

Overview

Name   ruvA   Type   Machinery gene
Locus tag   SPYM_RS08840 Genome accession   NC_009332
Coordinates   1759768..1760364 (-) Length   198 a.a.
NCBI ID   WP_011185063.1    Uniprot ID   A2RGV1
Organism   Streptococcus pyogenes str. Manfredo     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1754768..1765364
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPYM_RS08805 (SpyM51754) - 1754829..1755134 (-) 306 WP_002982199.1 DUF1292 domain-containing protein -
  SPYM_RS08810 (SpyM51755) ruvX 1755146..1755565 (-) 420 WP_002982196.1 Holliday junction resolvase RuvX -
  SPYM_RS08815 (SpyM51756) - 1755562..1755831 (-) 270 WP_002982194.1 IreB family regulatory phosphoprotein -
  SPYM_RS08820 (SpyM51757) spx 1755944..1756342 (-) 399 WP_002982188.1 transcriptional regulator Spx -
  SPYM_RS08825 (SpyM51758) recA 1756633..1757769 (-) 1137 WP_002982186.1 recombinase RecA -
  SPYM_RS08830 (SpyM51759) cinA 1757858..1759129 (-) 1272 WP_011018313.1 competence/damage-inducible protein A Machinery gene
  SPYM_RS08835 (SpyM51760) - 1759198..1759758 (-) 561 WP_010922755.1 DNA-3-methyladenine glycosylase I -
  SPYM_RS08840 (SpyM51761) ruvA 1759768..1760364 (-) 597 WP_011185063.1 Holliday junction branch migration protein RuvA Machinery gene
  SPYM_RS08845 (SpyM51762) - 1760366..1761586 (-) 1221 WP_011018316.1 MDR family MFS transporter -
  SPYM_RS08850 (SpyM51763) hexB 1761597..1763579 (-) 1983 WP_011889221.1 DNA mismatch repair endonuclease MutL Machinery gene
  SPYM_RS08855 (SpyM51764) - 1763674..1764691 (-) 1018 Protein_1718 tyrosine-type recombinase/integrase -

Sequence

Protein


Download         Length: 198 a.a.        Molecular weight: 21852.19 Da        Isoelectric Point: 6.4948

>NTDB_id=26517 SPYM_RS08840 WP_011185063.1 1759768..1760364(-) (ruvA) [Streptococcus pyogenes str. Manfredo]
MYDYIKGQLTKITAKYIVVEANGLGYMINVANPYSFTDSVNQLVTIYLHQVIREDAHLLFGFHTEDEKDVFLKLISVSGI
GPTTALAIVAVDDNEGLVNAIDNSDIKYLMKFPKIGKKTAQQMVLDLAGKFVEAPQETGHTKARSNKAGNTQLDEAIEAL
LALGYKATELKKIRAFFEGTSETAEQYIKSALKLLMKG

Nucleotide


Download         Length: 597 bp        

>NTDB_id=26517 SPYM_RS08840 WP_011185063.1 1759768..1760364(-) (ruvA) [Streptococcus pyogenes str. Manfredo]
ATGTACGATTATATTAAAGGTCAATTGACCAAAATTACGGCAAAATACATTGTCGTTGAAGCTAATGGATTGGGCTACAT
GATTAATGTTGCCAATCCTTATAGCTTTACAGATAGTGTCAACCAACTGGTAACTATTTACCTGCATCAAGTGATTCGTG
AGGATGCTCACTTGTTGTTTGGGTTTCATACGGAAGACGAAAAAGATGTTTTTCTGAAATTAATTTCTGTATCAGGCATT
GGTCCGACAACAGCTCTTGCTATTGTGGCAGTTGATGATAATGAGGGACTTGTGAATGCCATTGATAACAGTGACATTAA
GTACCTAATGAAATTTCCTAAAATTGGTAAAAAAACAGCGCAGCAAATGGTTCTTGACTTAGCTGGCAAATTTGTGGAGG
CTCCACAAGAGACTGGTCATACCAAAGCGCGCAGCAATAAAGCAGGCAATACTCAACTGGACGAAGCGATTGAAGCCCTC
CTTGCCCTCGGTTATAAAGCAACAGAGCTGAAAAAAATTCGTGCCTTCTTTGAGGGGACCTCTGAGACGGCAGAGCAATA
CATCAAATCAGCATTGAAACTGTTAATGAAAGGGTAG

Domains

Predicted by InterProScan.

RuvA N terminal domain (RuvA_N)

(1-61)

Helix-hairpin-helix domain (HHH_5)

(71-127)

RuvA, C-terminal domain (RuvA_C)

(152-196)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A2RGV1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ruvA Streptococcus pneumoniae TIGR4

66.497

99.495

0.662
  ruvA Streptococcus pneumoniae R6

66.497

99.495

0.662
  ruvA Streptococcus pneumoniae D39

66.497

99.495

0.662
  ruvA Bacillus subtilis subsp. subtilis str. 168

40.394

100

0.414

Multiple sequence alignment