Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   DXE52_RS22480 Genome accession   NZ_CP031347
Coordinates   4471043..4471633 (-) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli O145 strain RM9873-C1     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 4466043..4476633
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DXE52_RS22465 (DXE52_23105) uhpT 4466683..4468074 (-) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -
  DXE52_RS22470 (DXE52_23110) uhpC 4468212..4469531 (-) 1320 WP_001301991.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  DXE52_RS22475 (DXE52_23115) uhpB 4469541..4471043 (-) 1503 WP_001358729.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  DXE52_RS22480 (DXE52_23120) letA 4471043..4471633 (-) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  DXE52_RS22485 (DXE52_23125) - 4471795..4472898 (-) 1104 WP_001419235.1 hypothetical protein -
  DXE52_RS22490 (DXE52_23130) - 4473506..4473987 (-) 482 Protein_4368 hypothetical protein -
  DXE52_RS22495 (DXE52_23135) - 4474135..4474557 (-) 423 WP_180192625.1 hypothetical protein -
  DXE52_RS22500 - 4474629..4474787 (-) 159 WP_180192624.1 hypothetical protein -
  DXE52_RS22505 (DXE52_23140) ilvN 4475050..4475340 (-) 291 WP_001181706.1 acetolactate synthase small subunit -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=265145 DXE52_RS22480 WP_000633668.1 4471043..4471633(-) (letA) [Escherichia coli O145 strain RM9873-C1]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=265145 DXE52_RS22480 WP_000633668.1 4471043..4471633(-) (letA) [Escherichia coli O145 strain RM9873-C1]
ATGATCACCGTTGCCCTTATAGACGATCACCTCATCGTCCGCTCCGGCTTTGCGCAGTTGCTGGGGCTGGAACCTGATTT
GCAAGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCCGATATCTCCGGTCTGGAGCTGCTAAGCCAGCTGCCGAAAGGTATGGCGACAATTATGCTCTCCGTT
CATGACAGTCCGGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCGCGTGGCTTTCTCTCCAAGCGTTGTAGCCCTGACGA
ACTGATTGCTGCGGTGCATACGGTTGCCACAGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GCCAGGACCCACTAACCAAACGTGAACGGCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCCGCC
GAACTGGGCTTGTCACCGAAAACGGTACACGTCCATCGCGCCAATCTGATGGAAAAACTGGGCGTCAGTAACGACGTTGA
ACTGGCGCGCCGTATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378