Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   DXE54_RS06135 Genome accession   NZ_CP031343
Coordinates   1201490..1202146 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli O145 strain RM10425-C1     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1196490..1207146
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DXE54_RS06105 (DXE54_06305) dcyD 1197369..1198355 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  DXE54_RS06110 (DXE54_06310) tcyL 1198370..1199038 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  DXE54_RS06115 (DXE54_06315) tcyN 1199035..1199787 (+) 753 WP_001272991.1 L-cystine ABC transporter ATP-binding protein TcyN -
  DXE54_RS06120 (DXE54_06320) sdiA 1200017..1200739 (+) 723 WP_001154283.1 transcriptional regulator SdiA -
  DXE54_RS06125 (DXE54_06325) yecF 1200807..1201031 (-) 225 WP_000106476.1 DUF2594 family protein YecF -
  DXE54_RS06130 (DXE54_06330) yecU 1201018..1201194 (-) 177 WP_001307856.1 protein YecU -
  DXE54_RS06135 (DXE54_06335) letA 1201490..1202146 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  DXE54_RS06140 (DXE54_06340) uvrC 1202143..1203975 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  DXE54_RS06145 (DXE54_06345) pgsA 1204032..1204580 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  DXE54_RS06165 (DXE54_06365) - 1205276..1206016 (-) 741 WP_022581686.1 hypothetical protein -
  DXE54_RS27135 (DXE54_06370) - 1206097..1206573 (+) 477 Protein_1126 Arm DNA-binding domain-containing protein -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=264952 DXE54_RS06135 WP_000611328.1 1201490..1202146(+) (letA) [Escherichia coli O145 strain RM10425-C1]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=264952 DXE54_RS06135 WP_000611328.1 1201490..1202146(+) (letA) [Escherichia coli O145 strain RM10425-C1]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATCCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482

Multiple sequence alignment