Detailed information NTG0264944

Bioinformatically predicted

Overview

• Name: sxy/tfoX
• Type: Regulator
• Locus tag: CYK57_RS09850
• Genome accession: NZ_CP026009
• Coordinates: 2099047..2099703 (-)
• Length: 218 a.a.
• NCBI ID: WP_005609196.1
• Uniprot ID: A3N356
• Organism: Actinobacillus pleuropneumoniae strain App6
• Function: positive regulator of competence gene (predicted from homology) Competence regulation

Genomic Context

Location: 2094047..2104703

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CYK57_RS09830 (CYK57_02009)	nanA	2094421..2095299 (+)	879	WP_005599265.1	N-acetylneuraminate lyase	-
CYK57_RS09835 (CYK57_02010)	nagB	2095349..2096152 (+)	804	WP_005599267.1	glucosamine-6-phosphate deaminase	-
CYK57_RS09840 (CYK57_02011)	nagA	2096204..2097349 (+)	1146	WP_005599269.1	N-acetylglucosamine-6-phosphate deacetylase	-
CYK57_RS09845 (CYK57_02013)	fumC	2097498..2098892 (-)	1395	WP_005605803.1	class II fumarate hydratase	-
CYK57_RS09850 (CYK57_02014)	sxy/tfoX	2099047..2099703 (-)	657	WP_005609196.1	TfoX/Sxy family DNA transformation protein	Regulator
CYK57_RS09855 (CYK57_02016)	rpsJ	2100111..2100422 (+)	312	WP_001181005.1	30S ribosomal protein S10	-
CYK57_RS09860 (CYK57_02017)	rplC	2100448..2101074 (+)	627	WP_005599280.1	50S ribosomal protein L3	-
CYK57_RS09865 (CYK57_02018)	rplD	2101090..2101692 (+)	603	WP_005599282.1	50S ribosomal protein L4	-
CYK57_RS09870 (CYK57_02019)	rplW	2101689..2101994 (+)	306	WP_005599290.1	50S ribosomal protein L23	-
CYK57_RS09875 (CYK57_02020)	rplB	2102015..2102836 (+)	822	WP_005599291.1	50S ribosomal protein L2	-
CYK57_RS09880 (CYK57_02021)	rpsS	2102864..2103139 (+)	276	WP_005539416.1	30S ribosomal protein S19	-
CYK57_RS09885 (CYK57_02022)	rplV	2103150..2103482 (+)	333	WP_005599292.1	50S ribosomal protein L22	-
CYK57_RS09890 (CYK57_02023)	rpsC	2103501..2104208 (+)	708	WP_005599293.1	30S ribosomal protein S3	-
CYK57_RS09895 (CYK57_02024)	rplP	2104222..2104632 (+)	411	WP_005599294.1	50S ribosomal protein L16	-

Sequence

Protein

• Length: 218 a.a.
• Molecular weight: 25633.15 Da
• Isoelectric Point: 9.9359

>NTDB_id=264944 CYK57_RS09850 WP_005609196.1 2099047..2099703(-) (sxy/tfoX) [Actinobacillus pleuropneumoniae strain App6]
MAISPKKFQYLKEIFSPLGEINFKSYFSYLGIFKDDTMFALYDHKNDRLYLRKSAQFYPDIIRTIPIHFLIDRRIGKQQS
HIFYLIPSSIIHNLHLYTHWILSAIEEYQTAKAKLISQNKNKIRLLPNLNINIERLLARIEIYTVDDLKNVGVINAFVKL
IMLGLEVTELLLFKLYAALEHKYIYMLSKQEKQSLLIEADLSLYNAGLRKRFAISQAN

Nucleotide

• Length: 657 bp

>NTDB_id=264944 CYK57_RS09850 WP_005609196.1 2099047..2099703(-) (sxy/tfoX) [Actinobacillus pleuropneumoniae strain App6]
ATGGCAATATCCCCAAAAAAGTTCCAATATCTTAAGGAGATTTTTAGTCCTCTTGGAGAAATTAACTTCAAAAGCTATTT
TTCTTACTTAGGAATATTTAAAGACGATACTATGTTCGCCCTCTATGATCATAAAAACGATCGATTATACTTAAGAAAAT
CCGCTCAATTTTATCCGGATATTATAAGAACAATACCGATACATTTTTTAATTGATCGTCGTATCGGTAAGCAACAATCT
CATATTTTTTATCTTATACCTTCTTCTATTATTCACAATCTTCATTTATATACTCATTGGATTCTCTCTGCTATCGAAGA
ATATCAAACTGCAAAGGCCAAATTGATTTCTCAAAATAAAAATAAAATTCGTCTGCTTCCCAATTTGAATATCAATATAG
AAAGATTATTGGCACGTATTGAGATTTATACCGTAGATGATTTAAAAAACGTAGGCGTGATTAATGCGTTTGTAAAACTG
ATAATGCTAGGCTTGGAAGTAACCGAATTACTCCTCTTCAAACTCTACGCTGCGCTCGAACATAAATATATCTATATGTT
ATCCAAGCAAGAAAAACAATCCCTATTAATTGAAGCCGATTTATCTCTCTATAACGCAGGCCTACGTAAACGCTTCGCTA
TCTCACAGGCTAACTAA

Domains

Predicted by InterproScan.

• TfoX C-terminal domain (TfoX_C) (120-196)

• TfoX N-terminal domain (TfoX_N) (13-107)

3D structure

• AlphaFold DB: A3N356

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sxy/tfoX	Actinobacillus pleuropneumoniae strain HS143	100	100	1
sxy/tfoX	Actinobacillus suis H91-0380	63.721	98.624	0.628
sxy/tfoX	Glaesserella parasuis strain SC1401	39.234	95.872	0.376