Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrB   Type   Machinery gene
Locus tag   DV175_RS10970 Genome accession   NZ_CP031324
Coordinates   1858128..1860155 (-) Length   675 a.a.
NCBI ID   WP_002237998.1    Uniprot ID   -
Organism   Neisseria meningitidis strain M23347     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1853128..1865155
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DV175_RS10940 - 1853227..1854630 (+) 1404 WP_002237997.1 tetratricopeptide repeat protein -
  DV175_RS10945 trmB 1854752..1855468 (+) 717 WP_002235871.1 tRNA (guanosine(46)-N7)-methyltransferase TrmB -
  DV175_RS10950 - 1855800..1856147 (+) 348 WP_002235872.1 hypothetical protein -
  DV175_RS10960 - 1856307..1856747 (-) 441 WP_002235873.1 SMI1/KNR4 family protein -
  DV175_RS10965 - 1857116..1858093 (-) 978 WP_002235874.1 hypothetical protein -
  DV175_RS10970 uvrB 1858128..1860155 (-) 2028 WP_002237998.1 excinuclease ABC subunit UvrB Machinery gene
  DV175_RS14475 - 1860328..1860474 (-) 147 WP_153308396.1 hypothetical protein -
  DV175_RS10975 - 1860484..1861968 (-) 1485 WP_002237999.1 S41 family peptidase -
  DV175_RS10980 - 1862095..1863900 (-) 1806 WP_061837635.1 peptidoglycan DD-metalloendopeptidase family protein -
  DV175_RS10990 - 1864228..1864788 (+) 561 WP_002219151.1 CreA family protein -

Sequence

Protein


Download         Length: 675 a.a.        Molecular weight: 76865.25 Da        Isoelectric Point: 4.9636

>NTDB_id=264216 DV175_RS10970 WP_002237998.1 1858128..1860155(-) (uvrB) [Neisseria meningitidis strain M23347]
MEVIRYPDSPFKLHQPFPPAGDQPTAIADLLEGLSDGLAYQTLLGVTGSGKTYTMANVIAQSGRPAIIMAHNKTLAAQLY
AEMREFFPENAVEYFVSYYDYYQPEAYVPSRDLFIEKDSAINEHIEQMRLSATKNLMTRDDVIIVATVSAIYGIGDPTEY
QQMVLSVKEGDTIEQRDIIATLVSMQYERGDLDFKRGSFRVRGDVIDVYPAESSENALRISLFDDEIDRLDMFDPLSGSL
HQRVGRYTVFPSSHYVTPRDTVLRACESIKEELRERIDFFTKENRPVEQQRIEQRTRFDLEMLYEMGFCKGIENYSRHFS
GKKEGEPPPTLMDYLPDNAIMFIDESHVTVTQIGGMYKGDASRKQNLVDYGFRLPSARDNRPLKFHEFEKVMPQTVFVSA
TPAKYEEEHAGQVVEQVVRPTGLVDPQIIIRPVATQVDDLMSEINDRIQKGERVLVTTLTKRMAEQLTDYYSELGIKGRY
LHSDIDTVERVEIIRDLRLGLFDVLVGINLLREGLDIPEVSLVAILDADKEGFLRSHRSLIQTIGRAARNVNGVAILYAD
KITDSMKAAIDETERRREKQIKFNEEHGIVPQQIKKQVKDIIDGVYHEDDGGKGRRQGKNKVKVGEIHNEEDAIKEIAKL
EKAMQQAAKDLQFEEAAVLRDRIRGIKENLLFGAE

Nucleotide


Download         Length: 2028 bp        

>NTDB_id=264216 DV175_RS10970 WP_002237998.1 1858128..1860155(-) (uvrB) [Neisseria meningitidis strain M23347]
ATGGAAGTCATTCGATACCCCGATTCCCCCTTCAAACTCCACCAACCCTTCCCGCCCGCAGGCGACCAGCCTACCGCTAT
TGCCGACTTGCTCGAAGGGCTTTCAGACGGCCTTGCCTACCAAACCCTGCTCGGCGTAACCGGTTCGGGCAAAACCTACA
CCATGGCGAACGTCATCGCCCAAAGCGGCCGACCCGCCATCATCATGGCGCACAACAAAACCCTTGCCGCCCAGCTTTAT
GCCGAAATGCGCGAGTTTTTCCCTGAAAACGCGGTGGAATATTTCGTCTCCTACTACGACTATTACCAACCCGAAGCCTA
TGTGCCAAGCCGCGATTTGTTCATCGAAAAAGACAGTGCGATCAACGAACACATTGAACAAATGCGCCTTTCTGCCACCA
AAAACCTGATGACGCGCGATGACGTGATTATCGTTGCCACTGTGTCCGCCATTTACGGTATCGGCGACCCGACTGAGTAT
CAACAAATGGTGTTGTCCGTCAAAGAAGGCGACACCATCGAGCAGCGCGACATCATCGCCACGCTCGTTTCCATGCAGTA
CGAACGCGGCGATTTGGATTTCAAACGCGGCAGCTTCCGCGTGCGCGGCGACGTGATTGACGTGTACCCCGCCGAAAGCT
CCGAAAACGCCTTGCGTATCAGCCTGTTTGACGACGAAATCGACCGCCTCGATATGTTTGACCCGCTTTCAGGCAGCCTG
CACCAACGCGTCGGCCGCTACACCGTCTTCCCGTCCAGCCACTACGTTACCCCGCGCGACACCGTATTGCGCGCCTGCGA
GTCCATCAAAGAAGAATTGCGCGAACGCATTGATTTCTTTACCAAAGAAAACCGTCCCGTCGAGCAACAACGCATCGAAC
AGCGCACCCGTTTCGACCTCGAAATGCTCTACGAAATGGGCTTCTGCAAAGGTATCGAAAACTACTCCCGTCACTTCTCC
GGCAAAAAAGAAGGCGAACCGCCGCCCACGCTGATGGACTACCTGCCCGACAACGCCATCATGTTCATCGACGAAAGCCA
CGTTACCGTCACACAAATCGGCGGCATGTACAAAGGCGACGCATCGCGCAAGCAAAACCTCGTGGACTACGGCTTCCGCC
TACCTTCCGCCCGCGACAACCGCCCGCTCAAATTCCACGAATTTGAAAAAGTCATGCCGCAAACCGTCTTCGTTTCCGCC
ACCCCCGCCAAATACGAAGAAGAACACGCCGGACAAGTGGTCGAACAAGTCGTCCGCCCCACAGGGCTGGTCGACCCTCA
AATCATCATCCGCCCCGTCGCCACCCAAGTTGATGACTTAATGAGCGAAATCAACGACCGCATCCAAAAAGGCGAACGCG
TACTCGTTACCACCCTTACCAAACGCATGGCGGAGCAACTCACCGACTATTACAGCGAACTCGGCATCAAAGGGCGCTAC
CTGCACAGCGACATCGACACCGTAGAGCGCGTTGAAATTATTAGAGATTTGCGGCTCGGACTGTTTGACGTACTCGTCGG
CATCAACCTCTTGCGCGAAGGCCTCGACATCCCCGAAGTCTCCCTTGTTGCCATCCTCGACGCCGACAAAGAAGGCTTCC
TGCGCTCCCACCGCAGCCTGATTCAAACCATAGGCCGCGCCGCGCGCAACGTGAACGGCGTCGCCATCCTGTACGCCGAC
AAAATCACCGACTCCATGAAAGCCGCCATCGACGAAACCGAACGCCGCCGCGAAAAACAGATTAAATTCAACGAAGAACA
CGGTATTGTTCCGCAGCAGATTAAAAAACAGGTCAAAGACATCATCGACGGCGTGTACCACGAAGACGACGGCGGCAAAG
GCCGTAGACAAGGCAAAAACAAGGTTAAAGTCGGCGAAATCCACAACGAAGAAGACGCGATTAAAGAAATCGCCAAACTG
GAAAAAGCCATGCAGCAGGCAGCTAAGGATTTACAGTTTGAAGAAGCTGCTGTGTTGAGGGATAGGATACGGGGTATTAA
AGAGAATTTGTTGTTTGGGGCTGAGTAA

Domains

Predicted by InterProScan.

Ultra-violet resistance protein B (UvrB)

(557-598)

UvrB/uvrC motif (UVR)

(635-668)

Helicase conserved C-terminal domain (Helicase_C)

(444-549)

UvrB interaction domain (UvrB_inter)

(165-255)

Type III restriction enzyme, res subunit (ResIII)

(23-144)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrB Streptococcus pneumoniae TIGR4

55.354

98.222

0.544
  uvrB Streptococcus pneumoniae R6

55.354

98.222

0.544
  uvrB Streptococcus pneumoniae D39

55.354

98.222

0.544

Multiple sequence alignment