Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   DW289_RS07690 Genome accession   NZ_CP031321
Coordinates   1493287..1493919 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain ST2350 isolate Es_ST2350_SE1_NDM_03_2018     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1488287..1498919
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DW289_RS07660 (DW289_07660) yheS 1488457..1490370 (+) 1914 WP_000634798.1 ABC transporter ATP-binding protein -
  DW289_RS07665 (DW289_07665) yheT 1490370..1491392 (+) 1023 WP_000057346.1 hydrolase -
  DW289_RS07670 (DW289_07670) yheU 1491386..1491604 (+) 219 WP_000907085.1 YheU family protein -
  DW289_RS07675 (DW289_07675) prkB 1491658..1492527 (+) 870 WP_001274680.1 phosphoribulokinase -
  DW289_RS07680 (DW289_07680) yhfA 1492582..1492985 (-) 404 Protein_1404 OsmC family protein -
  DW289_RS07690 (DW289_07690) crp 1493287..1493919 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  DW289_RS07695 (DW289_07695) yhfK 1493970..1496060 (+) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  DW289_RS07700 (DW289_07700) argD 1496127..1497347 (-) 1221 WP_000963797.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  DW289_RS07705 (DW289_07705) pabA 1497433..1497996 (-) 564 WP_000601847.1 aminodeoxychorismate synthase component 2 -
  DW289_RS07710 (DW289_07710) fic 1498028..1498629 (-) 602 Protein_1409 putative adenosine monophosphate-protein transferase Fic -
  DW289_RS07715 (DW289_07715) yhfG 1498619..1498786 (-) 168 WP_000736860.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=264108 DW289_RS07690 WP_000242755.1 1493287..1493919(+) (crp) [Escherichia coli strain ST2350 isolate Es_ST2350_SE1_NDM_03_2018]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=264108 DW289_RS07690 WP_000242755.1 1493287..1493919(+) (crp) [Escherichia coli strain ST2350 isolate Es_ST2350_SE1_NDM_03_2018]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAACCTGGCAAAACAACCAGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment