Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrB   Type   Machinery gene
Locus tag   DV389_RS08185 Genome accession   NZ_CP031250
Coordinates   1673949..1675988 (+) Length   679 a.a.
NCBI ID   WP_114893613.1    Uniprot ID   -
Organism   Haemophilus influenzae strain M21384     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1668949..1680988
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DV389_RS08155 (DV389_08155) - 1669810..1670072 (-) 263 Protein_1546 type II toxin-antitoxin system YafQ family toxin -
  DV389_RS08160 (DV389_08160) - 1670069..1670344 (-) 276 WP_114893610.1 type II toxin-antitoxin system RelB/DinJ family antitoxin -
  DV389_RS08165 (DV389_08165) zevA 1670696..1671316 (+) 621 WP_114893611.1 zinc transporter binding subunit ZevA -
  DV389_RS08170 (DV389_08170) zevB 1671319..1672293 (+) 975 WP_114893612.1 zinc transporter permease subunit ZevB -
  DV389_RS09100 - 1672469..1672600 (-) 132 WP_111692007.1 hypothetical protein -
  DV389_RS08175 (DV389_08175) - 1672593..1673111 (-) 519 WP_232043373.1 ESPR domain-containing protein -
  DV389_RS08185 (DV389_08185) uvrB 1673949..1675988 (+) 2040 WP_114893613.1 excinuclease ABC subunit UvrB Machinery gene
  DV389_RS08190 (DV389_08190) - 1676019..1677944 (-) 1926 WP_050848565.1 LTA synthase family protein -
  DV389_RS08195 (DV389_08195) - 1678169..1680439 (-) 2271 WP_114893614.1 NADP-dependent malic enzyme -

Sequence

Protein


Download         Length: 679 a.a.        Molecular weight: 77568.04 Da        Isoelectric Point: 4.9950

>NTDB_id=263569 DV389_RS08185 WP_114893613.1 1673949..1675988(+) (uvrB) [Haemophilus influenzae strain M21384]
MSEKINTKPFILHSDFRPSGDQPQAIEKLAENLTDGLAYQTLLGVTGSGKTFTIANVIAQLNRPAMLLAPNKTLAAQLYA
EMKAFFPENAVEYFVSYYDYYQPEAYVPSSDTFIEKDASINDQIEQMRLSATKSFLERRDTIVVASVSAIYGLGDPDSYL
QMMLHLQQGAIIDQRQILAKLAELQYTRNDQAFQRGTFRVRGEIIDIFPAESDDRAVRIELFDDEIERLSLFDPLTGSSF
GAVPRFTIYPKTHYVTPRERILDAIENIKKELVSRREYFIKEHKLLEEQRISQRTQFDIEMMNELGYCSGIENYSRYLSG
RNEGEPPPTLFDYMPSDAILIIDESHVTVPQIGGMYRGDRSRKETLVEYGFRLPSALDNRPLRFEEFERLAPQTIYVSAT
PGPYELEKSGSEIIDQVVRPTGLLDPLIEIRPVSIQVDDLLSEARQRADKNERVLVTTLTKKMAEDLTDYLDEHGIRVRY
LHSDIDTVERVEIIRDLRLGEFDVLVGINLLREGLDIPEVSLVAILDADKEGFLRSERSLIQTIGRAARNLNGKAILYAD
SITKSMEKAITETNRRREKQTKYNEEHGIVPQALNKKVGELLDIGQGANQKAKANKQRGKMAAEPTALYNAPKNAKEYQQ
QIKKLEQQMYKFAQDLEFEKAAAIRDQLHQLREQFVFDN

Nucleotide


Download         Length: 2040 bp        

>NTDB_id=263569 DV389_RS08185 WP_114893613.1 1673949..1675988(+) (uvrB) [Haemophilus influenzae strain M21384]
ATGTCTGAAAAAATCAACACAAAACCGTTCATTCTGCATTCCGACTTTCGTCCTTCTGGCGATCAGCCACAAGCTATCGA
AAAATTAGCTGAAAATTTAACGGATGGATTGGCATATCAAACTTTGCTCGGAGTAACAGGCTCGGGGAAGACGTTTACTA
TCGCCAACGTAATCGCTCAATTAAATCGCCCCGCAATGTTACTTGCACCGAATAAAACCCTTGCGGCTCAACTTTATGCA
GAAATGAAAGCCTTTTTTCCAGAAAATGCGGTGGAATATTTTGTGTCTTACTATGATTATTATCAGCCAGAAGCCTATGT
GCCTAGCAGTGATACTTTCATTGAAAAAGATGCTTCTATTAATGATCAAATCGAACAAATGCGACTTTCTGCGACAAAAT
CTTTTTTAGAACGTCGAGATACCATCGTAGTGGCTTCCGTTTCTGCAATTTATGGTTTGGGCGATCCTGATAGCTACTTA
CAAATGATGTTGCATTTACAACAAGGTGCTATTATCGATCAACGTCAAATTTTAGCAAAGTTAGCTGAATTGCAATATAC
CCGCAATGATCAAGCATTTCAGCGTGGAACTTTCCGTGTTCGTGGGGAAATTATTGATATTTTCCCTGCAGAATCCGATG
ATCGTGCGGTGCGTATTGAATTATTTGATGATGAAATTGAACGATTAAGTTTATTTGATCCGCTCACTGGCAGTAGTTTT
GGTGCTGTTCCACGTTTTACGATCTATCCTAAAACGCACTATGTTACGCCAAGAGAACGCATTTTAGATGCGATAGAAAA
CATCAAAAAAGAACTCGTATCACGCCGTGAATACTTCATTAAAGAACATAAACTTTTAGAAGAACAACGAATTAGCCAAC
GAACCCAATTTGATATTGAAATGATGAATGAATTGGGCTATTGCTCGGGTATTGAAAACTACTCTCGCTATTTGTCAGGC
AGAAATGAAGGCGAGCCACCCCCAACATTGTTCGATTATATGCCCTCTGATGCCATTTTAATTATTGATGAATCTCATGT
GACCGTGCCTCAAATTGGTGGAATGTATCGTGGTGACCGTTCGCGCAAAGAAACCTTGGTTGAATATGGTTTCCGTTTAC
CGTCCGCATTGGATAATCGTCCGTTACGCTTTGAGGAATTTGAACGCTTAGCCCCACAAACCATCTATGTTTCCGCAACA
CCAGGGCCTTATGAATTAGAAAAATCAGGCAGTGAAATCATCGATCAAGTGGTTCGCCCAACTGGTTTACTTGATCCGCT
TATTGAAATTCGTCCAGTCTCAATTCAAGTGGATGATTTACTTTCTGAAGCTCGCCAAAGAGCGGATAAAAATGAGCGCG
TTTTAGTGACAACACTCACAAAAAAAATGGCAGAAGATTTAACGGATTATTTAGATGAACACGGAATCCGAGTACGTTAT
CTACATTCTGATATTGATACGGTGGAACGTGTGGAAATTATCCGTGATTTGCGTTTAGGAGAATTCGATGTGTTAGTCGG
CATCAACTTGCTACGTGAGGGATTGGATATTCCAGAAGTGTCTCTTGTGGCGATTTTAGATGCCGATAAAGAAGGATTTT
TACGCTCCGAACGTTCTTTAATCCAAACCATCGGCCGTGCTGCACGAAACTTAAATGGTAAAGCGATTTTATATGCGGAT
AGCATCACAAAATCAATGGAAAAAGCTATTACGGAAACTAATCGTCGTCGTGAAAAACAAACAAAATATAATGAAGAACA
TGGCATTGTGCCACAAGCATTGAATAAGAAAGTTGGGGAATTGTTAGATATTGGGCAAGGTGCAAACCAAAAAGCGAAAG
CCAATAAACAACGTGGAAAAATGGCGGCAGAACCAACCGCACTTTATAATGCACCGAAAAATGCCAAAGAATATCAACAA
CAAATCAAAAAATTGGAACAACAAATGTATAAATTTGCACAAGATTTGGAATTTGAAAAAGCCGCGGCAATTCGCGATCA
ATTACATCAATTGCGTGAACAATTTGTTTTTGATAACTAA

Domains

Predicted by InterProScan.

Type III restriction enzyme, res subunit (ResIII)

(20-102)

UvrB interaction domain (UvrB_inter)

(164-254)

Helicase conserved C-terminal domain (Helicase_C)

(446-549)

Ultra-violet resistance protein B (UvrB)

(557-598)

UvrB/uvrC motif (UVR)

(640-674)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrB Streptococcus pneumoniae TIGR4

57.44

98.969

0.568
  uvrB Streptococcus pneumoniae R6

57.44

98.969

0.568
  uvrB Streptococcus pneumoniae D39

57.44

98.969

0.568