Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrB   Type   Machinery gene
Locus tag   DV378_RS00090 Genome accession   NZ_CP031249
Coordinates   21772..23811 (+) Length   679 a.a.
NCBI ID   WP_114934724.1    Uniprot ID   -
Organism   Haemophilus influenzae strain M15895     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 16772..28811
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DV378_RS00060 - 17673..17936 (-) 264 WP_061671384.1 type II toxin-antitoxin system YafQ family toxin -
  DV378_RS00065 - 17933..18208 (-) 276 WP_050948473.1 type II toxin-antitoxin system RelB/DinJ family antitoxin -
  DV378_RS00070 zevA 18560..19180 (+) 621 WP_050846950.1 zinc transporter binding subunit ZevA -
  DV378_RS00075 zevB 19183..20157 (+) 975 WP_114934723.1 zinc transporter permease subunit ZevB -
  DV378_RS09760 - 20333..20527 (-) 195 WP_240320395.1 hypothetical protein -
  DV378_RS09765 - 20753..20974 (-) 222 WP_050948476.1 ESPR domain-containing protein -
  DV378_RS00090 uvrB 21772..23811 (+) 2040 WP_114934724.1 excinuclease ABC subunit UvrB Machinery gene
  DV378_RS00095 - 23842..25767 (-) 1926 WP_050948781.1 LTA synthase family protein -
  DV378_RS00100 - 26035..28305 (-) 2271 WP_050948477.1 NADP-dependent malic enzyme -

Sequence

Protein


Download         Length: 679 a.a.        Molecular weight: 77584.08 Da        Isoelectric Point: 5.0426

>NTDB_id=263447 DV378_RS00090 WP_114934724.1 21772..23811(+) (uvrB) [Haemophilus influenzae strain M15895]
MSEKINTKPFILHSDFRPSGDQPQAIEKLAENLTDGLAHQTLLGVTGSGKTFTIANVIAQLNRPAMLLAPNKTLAAQLYA
EMKAFFPENAVEYFVSYYDYYQPEAYVPSSDTFIEKDASINDQIEQMRLSATKSFLERRDTIVVASVSAIYGLGDPDSYL
QMMLHLQQGAIIDQRQILAKLAELQYTRNDQVFQRGTFRVRGEIIDIFPAESDDRAVRIELFDDEIERLSLFDPLTGSSF
GAVPRFTIYPKTHYVTPRERILDAIENIKKELVSRREYFIKEHKLLEEQRISQRTQFDIEMMNELGYCSGIENYSRYLSG
RNEGEPPPTLFDYMPSDAILIIDESHVTVPQIGGMYRGDRSRKETLVEYGFRLPSALDNRPLRFEEFERLAPQTIYVSAT
PGPYELEKSGSEIIDQVVRPTGLLDPLIEIRPVSIQVDDLLSEARQRADKNERVLVTTLTKKMAEDLTDYLDEHGIRVRY
LHSDIDTVERVEIIRDLRLGEFDVLVGINLLREGLDIPEVSLVAILDADKEGFLRSERSLIQTIGRAARNLNGKAILYAD
SITKSMEKAITETNRRREKQTKYNEEHGIVPQALNKKVGELLDIGQGANQKAKANKQRGKMAAEPTALYNAPKNAKEYQQ
QIKKLEQQMYKFAQDLEFEKAAAIRDQLHQLREQFVFEN

Nucleotide


Download         Length: 2040 bp        

>NTDB_id=263447 DV378_RS00090 WP_114934724.1 21772..23811(+) (uvrB) [Haemophilus influenzae strain M15895]
ATGTCTGAAAAAATCAACACAAAACCATTCATTCTTCATTCCGACTTTCGCCCCTCTGGCGATCAGCCACAAGCTATCGA
AAAATTGGCTGAAAATTTAACGGATGGATTGGCACATCAAACTTTGCTCGGAGTAACAGGCTCGGGGAAGACGTTTACTA
TCGCCAACGTAATCGCTCAATTAAATCGCCCCGCAATGTTACTTGCACCGAATAAAACCCTTGCCGCTCAACTTTATGCA
GAAATGAAAGCCTTTTTTCCAGAAAATGCGGTGGAATATTTTGTGTCTTACTATGATTATTATCAGCCAGAAGCCTATGT
GCCTAGCAGTGATACTTTCATTGAAAAAGATGCTTCTATTAATGATCAAATCGAACAAATGCGACTTTCTGCGACAAAAT
CTTTTTTAGAACGTCGAGATACCATCGTAGTGGCTTCCGTTTCTGCAATTTATGGTTTGGGCGATCCTGATAGCTACTTA
CAAATGATGTTGCATTTACAACAAGGTGCCATTATAGATCAACGCCAAATTTTAGCGAAGTTAGCGGAATTGCAATATAC
CCGCAATGATCAAGTATTTCAGCGTGGAACTTTCCGTGTTCGTGGGGAAATTATTGATATTTTCCCTGCAGAATCCGATG
ATCGTGCGGTGCGTATTGAATTATTTGATGATGAAATTGAACGATTAAGTTTATTTGATCCGCTCACTGGCAGTAGTTTT
GGTGCTGTTCCACGTTTTACGATCTATCCTAAAACGCACTATGTTACGCCAAGAGAACGCATTTTAGATGCGATAGAAAA
CATCAAAAAAGAACTCGTATCACGCCGTGAATACTTCATTAAAGAACATAAACTTTTAGAAGAACAACGAATTAGCCAAC
GAACCCAATTTGATATTGAAATGATGAATGAATTGGGCTATTGCTCGGGTATTGAAAACTACTCTCGCTATTTGTCAGGC
AGAAATGAAGGCGAGCCACCCCCAACATTATTTGATTATATGCCCTCTGATGCCATTTTAATTATTGATGAATCTCATGT
GACCGTGCCTCAAATTGGTGGAATGTATCGTGGTGACCGTTCGCGCAAAGAAACCTTGGTTGAATATGGTTTCCGTTTAC
CGTCCGCATTGGATAATCGTCCGTTACGCTTTGAGGAATTTGAACGCTTAGCCCCACAAACCATCTATGTTTCCGCAACA
CCAGGGCCCTATGAATTAGAAAAATCAGGCAGTGAAATCATCGATCAAGTGGTTCGCCCGACTGGTTTACTTGATCCGCT
TATTGAAATTCGTCCAGTCTCAATTCAAGTGGATGATTTACTTTCGGAAGCTCGCCAAAGAGCGGATAAAAATGAGCGCG
TTTTAGTGACAACACTCACTAAAAAAATGGCGGAAGATTTAACGGATTATTTAGATGAACATGGGATCCGAGTACGTTAT
CTACATTCTGATATTGATACGGTGGAACGTGTGGAAATTATCCGTGATTTGCGTTTAGGAGAATTCGATGTGTTAGTCGG
CATCAACTTGCTACGTGAGGGATTGGATATTCCAGAAGTGTCTCTTGTGGCGATTTTAGATGCGGACAAAGAAGGATTTT
TACGCTCCGAACGCTCTTTAATCCAAACCATCGGCCGTGCTGCACGAAACTTAAATGGTAAAGCGATTTTATATGCGGAT
AGCATCACAAAATCGATGGAAAAAGCTATTACGGAAACTAATCGTCGTCGTGAAAAACAAACAAAATATAATGAAGAACA
TGGCATTGTGCCACAAGCATTGAATAAGAAAGTTGGGGAATTGTTAGATATTGGGCAAGGTGCAAACCAAAAAGCGAAAG
CCAATAAACAACGTGGAAAAATGGCGGCAGAACCAACCGCACTTTATAATGCACCGAAAAATGCCAAAGAATATCAACAA
CAAATCAAAAAATTGGAACAACAAATGTATAAATTTGCACAAGATTTGGAATTTGAAAAAGCCGCGGCAATTCGCGATCA
ATTACATCAATTGCGTGAACAGTTTGTTTTTGAAAACTAA

Domains

Predicted by InterProScan.

UvrB/uvrC motif (UVR)

(640-674)

Helicase conserved C-terminal domain (Helicase_C)

(446-549)

UvrB interaction domain (UvrB_inter)

(164-254)

Ultra-violet resistance protein B (UvrB)

(557-598)

Type III restriction enzyme, res subunit (ResIII)

(20-102)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrB Streptococcus pneumoniae TIGR4

57.44

98.969

0.568
  uvrB Streptococcus pneumoniae R6

57.44

98.969

0.568
  uvrB Streptococcus pneumoniae D39

57.44

98.969

0.568