Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   DV130_RS09625 Genome accession   NZ_CP031248
Coordinates   1784630..1785529 (+) Length   299 a.a.
NCBI ID   WP_000904870.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain M26365     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1779630..1790529
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DV130_RS09590 - 1780050..1780343 (+) 294 WP_050072298.1 hypothetical protein -
  DV130_RS09595 - 1780499..1781713 (+) 1215 WP_000666469.1 pyridoxal phosphate-dependent aminotransferase -
  DV130_RS09600 rpmH 1781858..1781992 (+) 135 WP_000831905.1 50S ribosomal protein L34 -
  DV130_RS09605 - 1782231..1782920 (+) 690 WP_232035166.1 DUF1542 domain-containing protein -
  DV130_RS09615 - 1783225..1783998 (+) 774 WP_050072297.1 TatD family hydrolase -
  DV130_RS09620 rnmV 1783998..1784558 (+) 561 WP_000660015.1 ribonuclease M5 -
  DV130_RS09625 comR 1784630..1785529 (+) 900 WP_000904870.1 helix-turn-helix transcriptional regulator Regulator
  DV130_RS09630 - 1785849..1786145 (+) 297 WP_000815394.1 lactococcin 972 family bacteriocin -
  DV130_RS09635 - 1786222..1788252 (+) 2031 WP_050072296.1 bacteriocin-associated integral membrane family protein -
  DV130_RS09640 - 1788254..1788895 (+) 642 WP_000565531.1 ABC transporter ATP-binding protein -
  DV130_RS09645 - 1788888..1789196 (+) 309 WP_000333256.1 hypothetical protein -
  DV130_RS09650 rsmA 1789327..1790199 (+) 873 WP_001216869.1 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase RsmA -

Sequence

Protein


Download         Length: 299 a.a.        Molecular weight: 35351.12 Da        Isoelectric Point: 4.8336

>NTDB_id=263418 DV130_RS09625 WP_000904870.1 1784630..1785529(+) (comR) [Streptococcus pneumoniae strain M26365]
MLIGQKIKEIRIEKGVSRPDFCGDEQELTVRQLSRIESGASQPSLPKLAYIARRLGVPVYSLMPDFSALPPAYLELKYQI
LREPIYGKEEEYDKKEACLEEIYKTYFDNLPKEEQLACEVLQACLDTSRTRRPEYAELILEEHMSQIIEKEVYSTNDMLL
IRLFFYQMLIRKDLAKFINQIEKLMLFLLEQKKVTKLENFFIIRDTLISGMCCLEKVGVTDCFNDYLSCLQEIMDKTQDY
QKKPLVFMFLWKQALREERDFSLAESFYQSSKTFAQLIGDEFLVKKLTEEWQEDVKKYL

Nucleotide


Download         Length: 900 bp        

>NTDB_id=263418 DV130_RS09625 WP_000904870.1 1784630..1785529(+) (comR) [Streptococcus pneumoniae strain M26365]
ATGTTAATTGGTCAAAAAATTAAAGAGATTCGGATAGAAAAAGGAGTTAGTCGTCCAGATTTTTGTGGAGATGAGCAAGA
ACTGACAGTTCGTCAACTGTCGCGAATTGAAAGTGGAGCTTCGCAACCGAGTTTGCCCAAGTTAGCCTATATTGCTCGCC
GGCTAGGAGTTCCAGTTTATAGCCTTATGCCGGATTTTTCAGCTCTTCCTCCTGCTTATTTAGAATTGAAATACCAGATT
TTACGTGAACCAATCTATGGTAAAGAAGAGGAGTACGATAAGAAGGAAGCGTGTTTGGAAGAGATTTATAAAACATACTT
TGATAATCTTCCTAAAGAAGAACAATTAGCATGTGAAGTATTGCAGGCGTGTTTGGATACTTCTAGAACTAGAAGGCCTG
AATATGCAGAGTTAATACTTGAGGAACATATGTCTCAGATCATAGAAAAAGAAGTTTATTCAACAAATGATATGTTGTTG
ATTCGTTTGTTTTTTTATCAAATGCTCATTAGAAAAGATCTTGCCAAATTTATAAATCAAATCGAAAAGCTAATGCTCTT
TCTTTTGGAACAGAAAAAGGTAACTAAATTAGAAAACTTCTTTATAATTAGAGATACTCTTATTTCAGGAATGTGTTGTC
TTGAAAAGGTAGGAGTAACTGATTGTTTTAATGATTATCTATCGTGTTTACAAGAAATTATGGATAAAACTCAAGATTAT
CAAAAGAAACCTCTTGTATTTATGTTTTTGTGGAAGCAAGCATTAAGAGAAGAAAGAGATTTTAGTTTAGCTGAATCATT
TTATCAGTCTTCTAAAACATTTGCGCAGCTAATTGGAGATGAATTTCTAGTAAAGAAATTGACAGAGGAATGGCAAGAGG
ATGTCAAAAAATATTTATAA

Domains

Predicted by InterProScan.

ComR tetratricopeptide (ComR_TPR)

(70-291)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus mutans UA159

37.755

98.328

0.371
  comR Streptococcus suis P1/7

37.457

97.324

0.365
  comR Streptococcus suis 05ZYH33

37.457

97.324

0.365
  comR Streptococcus pyogenes MGAS8232

36.242

99.666

0.361