Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrB   Type   Machinery gene
Locus tag   DV130_RS01500 Genome accession   NZ_CP031248
Coordinates   281785..283773 (+) Length   662 a.a.
NCBI ID   WP_000607028.1    Uniprot ID   B1IC35
Organism   Streptococcus pneumoniae strain M26365     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 276785..288773
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DV130_RS01485 - 277679..278419 (-) 741 WP_001096316.1 amino acid ABC transporter ATP-binding protein -
  DV130_RS01490 - 278419..280584 (-) 2166 WP_000726258.1 ABC transporter substrate-binding protein/permease -
  DV130_RS01495 - 280754..281708 (+) 955 Protein_289 CPBP family intramembrane glutamic endopeptidase -
  DV130_RS01500 uvrB 281785..283773 (+) 1989 WP_000607028.1 excinuclease ABC subunit UvrB Machinery gene
  DV130_RS01505 - 283783..284346 (+) 564 WP_000639842.1 GNAT family protein -
  DV130_RS01510 - 284312..284821 (+) 510 WP_050072393.1 GNAT family N-acetyltransferase -
  DV130_RS01515 - 284874..285341 (+) 468 WP_000091559.1 NUDIX domain-containing protein -
  DV130_RS01520 - 285338..285853 (-) 516 WP_000159176.1 transcription repressor NadR -
  DV130_RS01525 - 285865..286392 (-) 528 WP_001097402.1 ECF transporter S component -
  DV130_RS01530 - 286656..287219 (-) 564 WP_000747408.1 ECF transporter S component -
  DV130_RS01535 coaC 287203..287754 (-) 552 WP_001284130.1 phosphopantothenoylcysteine decarboxylase -
  DV130_RS01540 coaB 287766..288455 (-) 690 WP_000699496.1 phosphopantothenate--cysteine ligase -

Sequence

Protein


Download         Length: 662 a.a.        Molecular weight: 75720.77 Da        Isoelectric Point: 4.5848

>NTDB_id=263338 DV130_RS01500 WP_000607028.1 281785..283773(+) (uvrB) [Streptococcus pneumoniae strain M26365]
MINHITDNQFKLVSKYQPSGDQPQAIEQLVDNIEGGEKAQILMGATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYG
EFKEFFPENAVEYFVSYYDYYQPEAYVPSSDTYIEKDSSVNDEIDKLRHSATSALLERNDVIVVASVSCIYGLGSPKEYA
DSVVSLRPGLEISRDKLLNDLVDIQFERNDIDFQRGRFRVRGDVVEIFPASRDEHAFRVEFFGDEIDRIREVEALTGQVL
GEVDHLAIFPATHFVTNDDHMEVAIAKIQAELEEQLAVFEKEGKLLEAQRLKQRTEYDIEMLREMGYTNGVENYSRHMDG
RSEGEPPYTLLDFFPDDFLIMIDESHMTIGQIKGMYNGDRSRKEMLVNYGFRLPSALDNRPLRREEFESHVHQIVYVSAT
PGDYENEQTETVIEQIIRPTGLLDPEVEVRPTMGQIDDLLGEINARVEKNERTFITTLTKKMAEDLTDYFKEMGIKVKYM
HSDIKTLERTEIIRDLRLGVFDVLVGINLLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSEGHVIMYADT
VTQSMQRAIDETARRRKIQMAYNEEHGIVPQTIKKEIRDLIAVTKAVAKEEDKEVDITSLNKQERKELVKKLEKQMQEAV
EVLDFELAAQIRDMMLEVKALD

Nucleotide


Download         Length: 1989 bp        

>NTDB_id=263338 DV130_RS01500 WP_000607028.1 281785..283773(+) (uvrB) [Streptococcus pneumoniae strain M26365]
ATGATCAATCACATTACAGATAATCAATTTAAACTAGTATCAAAATATCAACCATCAGGAGATCAACCCCAAGCTATCGA
GCAGTTGGTGGATAACATTGAGGGGGGAGAAAAAGCTCAGATTCTGATGGGGGCGACTGGAACAGGGAAGACCTATACTA
TGAGTCAGGTCATTTCTAAAGTCAATAAACCAACTCTGGTTATTGCCCACAATAAAACTCTGGCTGGTCAGCTCTATGGG
GAGTTTAAGGAATTTTTCCCTGAAAATGCAGTTGAGTATTTCGTATCCTACTATGATTATTACCAGCCAGAGGCCTATGT
CCCTTCTAGCGATACCTATATTGAGAAGGATAGTTCTGTCAATGACGAGATTGACAAGCTTCGCCACTCAGCTACCTCAG
CCCTTTTGGAGCGTAATGATGTTATTGTTGTGGCCTCAGTTTCTTGTATCTATGGTTTGGGTTCGCCCAAGGAATACGCT
GATAGTGTCGTTAGTCTCCGTCCTGGTCTAGAGATTTCTCGTGATAAACTCTTGAATGACTTGGTCGATATTCAGTTTGA
ACGTAATGATATTGATTTCCAACGCGGAAGATTTCGCGTTCGTGGGGATGTGGTAGAGATTTTCCCAGCTTCCCGAGATG
AACATGCCTTTCGAGTAGAATTTTTTGGAGACGAAATTGACCGTATTCGTGAAGTTGAGGCTCTGACAGGTCAGGTGTTG
GGAGAAGTGGATCATTTAGCGATTTTCCCAGCGACACACTTTGTGACCAATGACGACCACATGGAAGTTGCCATTGCAAA
GATTCAGGCCGAGTTGGAAGAACAATTAGCTGTCTTTGAAAAGGAAGGTAAACTGCTTGAAGCCCAGCGTTTGAAACAGC
GGACAGAGTATGATATCGAAATGTTGCGTGAGATGGGCTATACCAATGGGGTTGAAAATTATTCTCGCCACATGGATGGA
CGGAGCGAAGGAGAGCCTCCTTATACGCTTCTCGACTTCTTCCCAGATGATTTCTTGATTATGATTGACGAGAGTCATAT
GACCATAGGGCAAATCAAGGGCATGTACAATGGAGACCGTTCTCGTAAAGAAATGCTGGTTAATTATGGTTTCCGTTTGC
CGTCTGCTTTGGACAATCGTCCTCTCCGTCGGGAGGAGTTTGAGAGTCACGTTCATCAGATTGTTTACGTTTCAGCGACA
CCTGGTGACTATGAAAATGAACAGACCGAGACAGTGATTGAGCAAATCATTCGTCCAACGGGACTCTTGGATCCAGAGGT
GGAAGTCCGTCCGACTATGGGACAGATTGATGACCTCTTGGGTGAAATCAATGCCCGCGTTGAAAAAAATGAGCGTACCT
TTATCACAACTTTGACCAAGAAAATGGCAGAGGACTTGACCGACTACTTCAAGGAAATGGGTATCAAGGTTAAGTACATG
CACTCGGATATCAAGACCTTGGAACGGACGGAGATTATCCGTGACCTGCGCTTGGGTGTCTTTGATGTCTTGGTCGGAAT
TAACCTGCTCCGTGAAGGAATTGACGTTCCTGAAGTGAGCCTCGTAGCTATTCTCGATGCTGACAAGGAAGGTTTCCTTC
GCAACGAACGTGGACTCATCCAGACTATTGGACGTGCTGCTCGTAACAGTGAAGGCCATGTCATCATGTATGCAGACACG
GTTACCCAGTCTATGCAACGTGCTATCGATGAAACTGCCCGCCGTCGGAAAATTCAGATGGCCTATAATGAAGAGCATGG
TATCGTACCACAGACAATCAAGAAAGAAATCCGTGACCTGATTGCTGTGACCAAGGCAGTTGCTAAGGAAGAGGACAAGG
AAGTCGACATCACTAGCCTCAACAAACAAGAGCGAAAAGAACTCGTCAAGAAACTAGAAAAACAAATGCAAGAAGCCGTC
GAAGTGCTTGACTTTGAACTGGCGGCTCAGATCCGTGATATGATGTTGGAAGTCAAGGCCTTGGATTAG

Domains

Predicted by InterProScan.

Ultra-violet resistance protein B (UvrB)

(556-598)

UvrB/uvrC motif (UVR)

(626-660)

Type III restriction enzyme, res subunit (ResIII)

(17-143)

UvrB interaction domain (UvrB_inter)

(164-254)

Helicase conserved C-terminal domain (Helicase_C)

(443-549)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB B1IC35

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrB Streptococcus pneumoniae TIGR4

99.849

100

0.998
  uvrB Streptococcus pneumoniae R6

99.698

100

0.997
  uvrB Streptococcus pneumoniae D39

99.698

100

0.997