Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   C0649_RS12725 Genome accession   NZ_CP025685
Coordinates   2498183..2499424 (-) Length   413 a.a.
NCBI ID   WP_002293079.1    Uniprot ID   A0AB73A9G3
Organism   Enterococcus faecium strain CBA7134     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 2493183..2504424
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C0649_RS12710 (C0649_12710) proC 2494165..2494971 (+) 807 WP_002293075.1 pyrroline-5-carboxylate reductase -
  C0649_RS12715 (C0649_12715) rny 2495050..2496606 (-) 1557 WP_002287336.1 ribonuclease Y -
  C0649_RS12720 (C0649_12720) recA 2497025..2498074 (-) 1050 WP_002293077.1 recombinase RecA Machinery gene
  C0649_RS12725 (C0649_12725) cinA 2498183..2499424 (-) 1242 WP_002293079.1 competence/damage-inducible protein A Machinery gene
  C0649_RS12730 (C0649_12730) pgsA 2499595..2500173 (-) 579 WP_002293081.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  C0649_RS12740 (C0649_12740) - 2500382..2501305 (-) 924 WP_002336183.1 RodZ domain-containing protein -
  C0649_RS12745 (C0649_12745) - 2501797..2503083 (-) 1287 WP_128251840.1 pitrilysin family protein -
  C0649_RS12750 (C0649_12750) - 2503076..2504344 (-) 1269 WP_002293085.1 pitrilysin family protein -

Sequence

Protein


Download         Length: 413 a.a.        Molecular weight: 45406.91 Da        Isoelectric Point: 4.8009

>NTDB_id=263296 C0649_RS12725 WP_002293079.1 2498183..2499424(-) (cinA) [Enterococcus faecium strain CBA7134]
MKAEIIAVGTELLLGQVVNTNATFLSEQLADLGIEVYYQTVVGDNQQRLEELIALAETRSELILLCGGLGPTEDDLTKEA
TAAHLGKSLIQNTEGYKKLLAYFETTHRKMTKNNLQQSQIIEGGVPLPNRTGLALGTFYQTDTHAYILLPGPPNELKPMF
VEQVRPLLEERFPSEEKLISKVLRFYGIGESRLVTELKDLIETQINPTIAPYAKPNEVTLRLTVKTKDVQAGNQALLALE
EKIQERVGEYFYGYGDDNSLAKVVVELLKANKQTVTAAESLTAGAFQAALGDIAGVSDVFPGGFVTYSLQTKAGFLEIDP
ELLAEYGTVSKECVEQMAIQAREIARTDYSVAFTGVAGPDMLEGHPAGTVWIAISSKDGVVSEKYHFARDRAAIRYNAVM
QGFDLLRKQLLRK

Nucleotide


Download         Length: 1242 bp        

>NTDB_id=263296 C0649_RS12725 WP_002293079.1 2498183..2499424(-) (cinA) [Enterococcus faecium strain CBA7134]
ATGAAAGCAGAAATAATAGCTGTCGGAACAGAACTTTTACTAGGACAAGTCGTGAATACGAATGCCACTTTCTTGTCAGA
ACAGCTAGCTGATCTAGGTATCGAAGTTTATTATCAGACAGTCGTAGGAGATAATCAGCAGCGTTTAGAAGAGTTGATTG
CTCTAGCTGAAACAAGAAGTGAACTCATACTCTTATGTGGCGGATTAGGGCCGACAGAAGATGACCTGACAAAAGAAGCA
ACTGCGGCTCACCTCGGTAAGTCTCTCATACAAAATACGGAAGGATACAAAAAATTATTGGCATATTTTGAAACAACCCA
TCGAAAAATGACCAAAAACAATCTGCAACAGTCTCAAATCATCGAAGGCGGGGTTCCTCTACCAAATCGTACAGGGCTTG
CTTTAGGGACTTTTTATCAAACAGATACACATGCATATATCCTTCTTCCCGGTCCGCCTAATGAGTTGAAACCAATGTTT
GTGGAACAAGTACGTCCTTTACTAGAGGAACGTTTTCCTTCTGAAGAAAAACTGATTTCTAAAGTTTTGCGCTTTTATGG
GATTGGTGAATCGCGACTGGTCACTGAACTAAAAGATCTGATTGAAACACAGATCAATCCAACGATCGCTCCTTATGCCA
AACCAAATGAAGTGACATTGCGTCTAACAGTGAAAACAAAGGATGTTCAGGCAGGAAATCAAGCTCTTTTAGCATTGGAA
GAAAAGATTCAAGAACGAGTAGGAGAATATTTTTATGGATATGGCGATGATAATTCGTTAGCAAAAGTCGTAGTGGAACT
GCTGAAAGCAAACAAGCAGACTGTAACAGCGGCGGAAAGCTTGACAGCCGGTGCCTTCCAAGCCGCATTGGGCGATATTG
CTGGTGTATCTGATGTATTTCCAGGCGGCTTCGTTACCTACTCGCTCCAAACAAAAGCTGGTTTTCTGGAGATTGATCCG
GAGCTATTAGCAGAATATGGAACAGTCAGCAAAGAATGTGTGGAGCAGATGGCCATTCAAGCACGTGAGATAGCAAGAAC
AGATTACAGTGTAGCTTTCACCGGAGTGGCTGGACCGGACATGTTAGAAGGTCACCCTGCAGGAACAGTATGGATCGCTA
TTTCATCTAAAGATGGCGTGGTTTCAGAAAAATATCATTTTGCCAGAGACCGTGCGGCTATCAGATATAATGCGGTTATG
CAAGGATTTGATCTTTTGAGAAAACAGCTTTTAAGAAAATGA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)

Damage-inducible protein CinA KH domain (CinA_KH)

(180-253)

Competence-damaged protein (CinA)

(258-410)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mitis SK321

51.667

100

0.525
  cinA Streptococcus pneumoniae TIGR4

51.429

100

0.523
  cinA Streptococcus pneumoniae D39

51.19

100

0.521
  cinA Streptococcus pneumoniae Rx1

51.19

100

0.521
  cinA Streptococcus pneumoniae R6

51.19

100

0.521
  cinA Streptococcus mitis NCTC 12261

51.19

100

0.521
  cinA Streptococcus mutans UA159

51.566

100

0.518
  cinA Bacillus subtilis subsp. subtilis str. 168

47.573

99.758

0.475
  cinA Streptococcus suis isolate S10

41.546

100

0.416

Multiple sequence alignment