Detailed information    

insolico Bioinformatically predicted

Overview

Name   brsR   Type   Regulator
Locus tag   DV131_RS03990 Genome accession   NZ_CP031246
Coordinates   727930..728370 (-) Length   146 a.a.
NCBI ID   WP_050211521.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain M26368     
Function   antagonizing the proteolysis of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 722930..733370
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DV131_RS03960 - 723191..724477 (+) 1287 WP_050075994.1 response regulator transcription factor -
  DV131_RS03965 - 724529..725062 (+) 534 WP_000729029.1 hypothetical protein -
  DV131_RS03970 nrdI 725140..725610 (+) 471 WP_000849621.1 class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI -
  DV131_RS03980 - 725903..727165 (-) 1263 WP_000075789.1 NRAMP family divalent metal transporter -
  DV131_RS03985 - 727475..727933 (-) 459 WP_050211520.1 DUF3021 domain-containing protein -
  DV131_RS03990 brsR 727930..728370 (-) 441 WP_050211521.1 LytTR family DNA-binding domain-containing protein Regulator
  DV131_RS04000 hexB 728576..730525 (+) 1950 WP_000018169.1 DNA mismatch repair endonuclease MutL Machinery gene
  DV131_RS04005 ribE 730851..731318 (-) 468 WP_001099502.1 6,7-dimethyl-8-ribityllumazine synthase -
  DV131_RS04010 - 731319..732524 (-) 1206 WP_001820536.1 bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II -
  DV131_RS04015 ribE 732544..733179 (-) 636 WP_000493842.1 riboflavin synthase -

Sequence

Protein


Download         Length: 146 a.a.        Molecular weight: 17213.87 Da        Isoelectric Point: 5.3783

>NTDB_id=263144 DV131_RS03990 WP_050211521.1 727930..728370(-) (brsR) [Streptococcus pneumoniae strain M26368]
MKVELQISETYEEEKLIVQAPQETEKVQKVIEFAENLDQREKIKGKIDDQVYLVEIGKIQRFYIENRKVLAETTSQTYSI
DLRLYQVLKLLPTNFIQISQSEIINIDSISHLKLTPNGLVEIFLKNESFTYSSRRYLKTIKEKLEL

Nucleotide


Download         Length: 441 bp        

>NTDB_id=263144 DV131_RS03990 WP_050211521.1 727930..728370(-) (brsR) [Streptococcus pneumoniae strain M26368]
ATGAAAGTAGAACTACAGATTAGTGAGACTTACGAGGAGGAAAAGCTGATTGTCCAAGCACCTCAAGAAACCGAAAAAGT
CCAGAAAGTCATCGAGTTCGCAGAAAATCTGGACCAAAGAGAAAAAATCAAAGGAAAAATCGATGATCAGGTCTATCTAG
TTGAGATTGGCAAGATTCAGCGCTTCTATATCGAGAATCGGAAGGTTCTAGCAGAAACCACGAGTCAGACCTACAGCATT
GATTTGCGACTCTATCAGGTTCTTAAACTCTTGCCAACCAATTTTATCCAAATTTCCCAATCAGAAATCATCAATATCGA
TTCCATCTCTCACCTCAAGCTCACGCCAAACGGTCTGGTAGAAATTTTCTTGAAAAACGAAAGCTTCACCTACTCTTCAC
GCCGTTATCTAAAAACCATCAAGGAGAAATTAGAACTATGA

Domains

Predicted by InterProScan.

LytTr DNA-binding domain (LytTR)

(50-144)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  brsR Streptococcus mutans UA159

36.054

100

0.363

Multiple sequence alignment