Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   DVH14_RS22200 Genome accession   NZ_CP031231
Coordinates   4503287..4503919 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain Es_ST410_NW1_NDM_09_2017     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 4498287..4508919
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DVH14_RS22175 (DVH14_23430) yheS 4498456..4500369 (+) 1914 WP_000634789.1 ABC transporter ATP-binding protein -
  DVH14_RS22180 (DVH14_23435) yheT 4500369..4501391 (+) 1023 WP_000057380.1 hydrolase -
  DVH14_RS22185 (DVH14_23440) yheU 4501385..4501603 (+) 219 WP_000907085.1 YheU family protein -
  DVH14_RS22190 (DVH14_23445) prkB 4501657..4502526 (+) 870 WP_001274680.1 phosphoribulokinase -
  DVH14_RS22195 (DVH14_23450) yhfA 4502581..4502985 (-) 405 WP_001148908.1 OsmC family protein -
  DVH14_RS22200 (DVH14_23460) crp 4503287..4503919 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  DVH14_RS22205 (DVH14_23465) yhfK 4503970..4506060 (+) 2091 WP_001356225.1 YccS/YhfK family putative transporter -
  DVH14_RS22210 (DVH14_23470) argD 4506127..4507347 (-) 1221 WP_000963785.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  DVH14_RS22215 (DVH14_23475) pabA 4507433..4507996 (-) 564 WP_000601847.1 aminodeoxychorismate synthase component 2 -
  DVH14_RS22220 (DVH14_23480) fic 4508028..4508630 (-) 603 WP_001280624.1 putative adenosine monophosphate-protein transferase Fic -
  DVH14_RS22225 (DVH14_23485) yhfG 4508620..4508787 (-) 168 WP_000736860.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=262652 DVH14_RS22200 WP_000242755.1 4503287..4503919(+) (crp) [Escherichia coli strain Es_ST410_NW1_NDM_09_2017]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=262652 DVH14_RS22200 WP_000242755.1 4503287..4503919(+) (crp) [Escherichia coli strain Es_ST410_NW1_NDM_09_2017]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAACCTGGCAAAACAACCAGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment