Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   C6669_RS11215 Genome accession   NZ_CP031134
Coordinates   2170046..2170678 (-) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain CFSAN064035     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2165046..2175678
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C6669_RS11190 (C6669_11190) yhfG 2165178..2165345 (+) 168 WP_000736860.1 YhfG family protein -
  C6669_RS11195 (C6669_11195) fic 2165335..2165937 (+) 603 WP_001280624.1 putative adenosine monophosphate-protein transferase Fic -
  C6669_RS11200 (C6669_11200) pabA 2165969..2166532 (+) 564 WP_000601847.1 aminodeoxychorismate synthase component 2 -
  C6669_RS11205 (C6669_11205) argD 2166618..2167838 (+) 1221 WP_000963797.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  C6669_RS11210 (C6669_11210) yhfK 2167905..2169995 (-) 2091 WP_001297515.1 YccS/YhfK family putative transporter -
  C6669_RS11215 (C6669_11215) crp 2170046..2170678 (-) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  C6669_RS11225 (C6669_11225) yhfA 2170980..2171384 (+) 405 WP_001148908.1 OsmC family protein -
  C6669_RS11230 (C6669_11230) prkB 2171439..2172308 (-) 870 WP_001274683.1 phosphoribulokinase -
  C6669_RS11235 (C6669_11235) yheU 2172362..2172580 (-) 219 WP_000907085.1 YheU family protein -
  C6669_RS11240 (C6669_11240) yheT 2172574..2173596 (-) 1023 WP_000057410.1 hydrolase -
  C6669_RS11245 (C6669_11245) yheS 2173596..2175509 (-) 1914 WP_000634793.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=262372 C6669_RS11215 WP_000242755.1 2170046..2170678(-) (crp) [Escherichia coli strain CFSAN064035]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=262372 C6669_RS11215 WP_000242755.1 2170046..2170678(-) (crp) [Escherichia coli strain CFSAN064035]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAACCTGGCAAAACAACCAGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment