Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   DR994_RS04135 Genome accession   NZ_CP030927
Coordinates   802284..803024 (-) Length   246 a.a.
NCBI ID   WP_173940476.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain CS9     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 797284..808024
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DR994_RS04120 (DR994_04250) comB 799270..800631 (+) 1362 WP_173940475.1 bacteriocin secretion accessory protein Regulator
  DR994_RS04125 (DR994_04255) - 800730..800885 (+) 156 WP_096811960.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  DR994_RS04130 (DR994_04260) - 800933..802273 (-) 1341 WP_039671036.1 GHKL domain-containing protein -
  DR994_RS04135 (DR994_04265) comE/blpR 802284..803024 (-) 741 WP_173940476.1 response regulator transcription factor Regulator
  DR994_RS04140 (DR994_04270) - 803026..803367 (-) 342 WP_024404826.1 LytTR family DNA-binding domain-containing protein -
  DR994_RS09910 - 803566..803961 (+) 396 WP_232085807.1 hypothetical protein -
  DR994_RS04150 (DR994_04280) - 803894..805777 (-) 1884 WP_173940477.1 SAG1250 family conjugative relaxase -
  DR994_RS04155 (DR994_04285) mobC 805764..806129 (-) 366 WP_039671039.1 plasmid mobilization relaxosome protein MobC -
  DR994_RS04160 (DR994_04290) - 806132..806494 (-) 363 WP_039671040.1 SAG1252 family conjugative relaxosome accessory protein -

Sequence

Protein


Download         Length: 246 a.a.        Molecular weight: 28895.09 Da        Isoelectric Point: 6.7719

>NTDB_id=261769 DR994_RS04135 WP_173940476.1 802284..803024(-) (comE/blpR) [Streptococcus thermophilus strain CS9]
MNIFVMEDDFMQQARIEKIITKLLEKHNIVPKKFEISGEPHQLLQAIEEKGVHQLFFLDIEIKEDELKGLQVAKQIREID
PYASIVFVTTHSEFMPLSFRYQVSALDYIDKELGVTEFESRIEAALLHTHNKDNSAVSDDSFYFKSKYAQVQYPFNEVYY
IETSPRPHRVILYTKTDRMEFTASLSDILKQDKRLVQCHRSFAINPRNVVKVDRNEKQIYFPNGATCFISRQKLESTLAV
IDRLHR

Nucleotide


Download         Length: 741 bp        

>NTDB_id=261769 DR994_RS04135 WP_173940476.1 802284..803024(-) (comE/blpR) [Streptococcus thermophilus strain CS9]
ATGAATATCTTTGTAATGGAAGATGATTTTATGCAACAAGCGAGAATTGAGAAGATTATTACTAAGCTGTTAGAAAAGCA
CAACATCGTTCCGAAAAAATTTGAAATTTCAGGAGAACCTCATCAGCTACTTCAAGCAATAGAAGAAAAAGGAGTACATC
AGCTCTTCTTTTTAGATATTGAGATTAAGGAAGACGAACTAAAAGGACTTCAAGTCGCTAAACAAATTAGAGAGATTGAC
CCTTATGCTAGTATTGTTTTTGTGACAACACACTCCGAGTTTATGCCCTTATCTTTCAGGTACCAGGTATCTGCCTTGGA
CTATATTGACAAAGAGCTTGGAGTTACCGAATTTGAATCGCGAATAGAAGCAGCTTTACTTCATACTCACAATAAGGACA
ATAGCGCCGTATCGGATGATTCATTCTATTTTAAGTCCAAATATGCTCAAGTACAATACCCATTCAATGAAGTGTACTAC
ATCGAGACTTCTCCCCGCCCTCATCGTGTTATCCTTTATACCAAGACAGACCGAATGGAGTTCACAGCAAGTTTGTCAGA
CATTTTGAAACAAGATAAACGACTTGTACAATGTCATCGTTCGTTTGCAATCAATCCGAGGAATGTTGTTAAAGTGGATA
GAAATGAAAAACAGATCTACTTTCCTAATGGAGCCACCTGTTTTATTTCAAGGCAAAAGCTAGAATCAACTTTAGCTGTT
ATTGATAGACTGCATAGATAA

Domains

Predicted by InterProScan.

LytTr DNA-binding domain (LytTR)

(151-235)

Response regulator receiver domain (Response_reg)

(3-122)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

53.306

98.374

0.524
  comE/comE1 Streptococcus equinus JB1

41.423

97.154

0.402
  comE/comE2 Streptococcus equinus JB1

36.885

99.187

0.366

Multiple sequence alignment